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Synthesis and reactions of 2-substituted 1-phenyl-4-oxo-1,4-dihydropyrido-[2,3-d]pyrimidines

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

2-Methyl-4-oxo-1-phenyl-1,4-dihydropyrido[2,3-d]pyrimidine was acylated by succinic and trifluoroacetic anhydrides and also underwent the Claisen reaction with diethyl oxalate and ethyl oxanilate to give acyl derivatives at the methyl group, which, according to UV, IR, and1H NMR spectra, exist as enaminocarbonyl and iminoenol tautomers with intramolecular hydrogen bonds.

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Perm State Pharmaceutical Academy, Perm 614600, Russia. e-mail: GIO@pharm.perm.su. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1119–1122, August, 2000.

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Gavrilov, M.Y., Kon'shin, M.E. & Zakharov, A.V. Synthesis and reactions of 2-substituted 1-phenyl-4-oxo-1,4-dihydropyrido-[2,3-d]pyrimidines. Chem Heterocycl Compd 36, 981–984 (2000). https://doi.org/10.1007/BF02256985

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  • DOI: https://doi.org/10.1007/BF02256985

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