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Advances in the study on induced pluripotent stem cells

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  • Cell Biology
  • Published:
Chinese Science Bulletin

Abstract

Recently, the study on “induced pluripotent stem cells” (iPS cells) has made a great breakthrough, and it is considered as a new milestone in the history of life science. This progress has updated our traditional concepts about pluripotency control, and provided people with a brand-new strategy for somatic cell nuclear reprogramming. In virtue of its availability and stability, this method holds great potential in both biological and clinical research. In order to introduce this rising field of study, this paper starts with an overview of the development of iPS cell establishment, describes the key steps in generating iPS cells, elaborates several relevant scientific issues, and evaluates its current restrictions and promises in future research.

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Authors and Affiliations

  1. State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China

    Shuang Liu & EnKui Duan

  2. Graduate University of the Chinese Academy of Sciences, Beijing, 100049, China

    Shuang Liu

Authors
  1. Shuang Liu
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  2. EnKui Duan
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Corresponding author

Correspondence to EnKui Duan.

Additional information

Supported by the National Basic Research Program of China (Grant No. 2007CB947401) and Chinese National Manned Space Program (Grant No. 921-2)

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Liu, S., Duan, E. Advances in the study on induced pluripotent stem cells. Chin. Sci. Bull. 53, 709–717 (2008). https://doi.org/10.1007/s11434-008-0152-5

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  • DOI: https://doi.org/10.1007/s11434-008-0152-5

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