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Lanthanum Potentiates GABA-Activated Currents in Rat Pyramidal Neurons of CA1 Hippocampal Field

  • Biophysics and Biochemistry
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Bulletin of Experimental Biology and Medicine Aims and scope

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Abstract

In CA1 hippocampal pyramidal neurons, lanthanum ions increased the amplitude of GABA-activated currents and shifted the dose-dependence curve to the left, which attests to increased affinity of GABAA-receptors to GABA. The data made it possible to compare the sensitivity GABAA-receptors of pyramidal neurons and similar receptors of other cells to GABA and lanthanum.

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Translated from Byulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 140, No. 10, pp. 398–401, October, 2005

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Boldyreva, A.A. Lanthanum Potentiates GABA-Activated Currents in Rat Pyramidal Neurons of CA1 Hippocampal Field. Bull Exp Biol Med 140, 403–405 (2005). https://doi.org/10.1007/s10517-005-0503-z

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  • DOI: https://doi.org/10.1007/s10517-005-0503-z

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