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Larvicidal and repellent activity of the essential oil of Coriandrum sativum L. (Apiaceae) fruits against the filariasis vector Aedes albopictus Skuse (Diptera: Culicidae)

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Abstract

The essential oils of many Apiaceae species have been already studied for their insecticidal and repellent properties against insect pests. In this research, the essential oil (EO) extracted from the fruits of Coriandrum sativum L. (Apiaceae) was evaluated for the first time for its larvicidal and repellent activities against the most invasive mosquito worldwide, Aedes albopictus Skuse (Diptera: Culicidae). The chemical composition of C. sativum EO was investigated by gas chromatography with electron impact mass spectrometry analysis. Coriander EO was mainly composed by monoterpene hydrocarbons and oxygenated monoterpenes, with linalool (83.6 %) as the major constituent. C. sativum EO exerted toxic activity against A. albopictus larvae: LC50 was 421 ppm, while LC90 was 531.7 ppm. Repellence trials highlighted that C. sativum EO was a good repellent against A. albopictus, also at lower dosages: RD50 was 0.0001565 μL/cm2 of skin, while RD90 was 0.002004 μL/cm2. At the highest dosage (0.2 μL/cm2 of skin), the protection time achieved with C. sativum essential oil was higher than 60 min. This study adds knowledge about the chemical composition of C. sativum EO as well as to the larvicidal and repellent activity exerted by this EO against A. albopictus. On this basis, we believe that our findings could be useful for the development of new and safer products against the Asian tiger mosquito.

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References

  • Adams RP (1995) Identification of essential oil components by gas chromatography-mass spectroscopy. Allured, Carol Stream

    Google Scholar 

  • Amer A, Mehlhorn H (2006a) Larvicidal effects of various essential oils against Aedes, Anopheles, and Culex larvae (Diptera, Culicidae). Parasitol Res 99:466–472

    Article  PubMed  Google Scholar 

  • Amer A, Mehlhorn H (2006b) Repellency effect of forty-one essential oils against Aedes, Anopheles and Culex mosquitoes. Parasitol Res 99:478–490

    Article  PubMed  Google Scholar 

  • Ateyyat MA, Al-Mazra’awi M, Abu-Rjai T, Shatnawi MA (2009) Aqueous extracts of some medicinal plants are as toxic as Imidacloprid to the sweet potato whitefly, Bemisia tabaci. J Ins Sci 9:15–21

    Google Scholar 

  • Bakkali F, Averbeck S, Averbeck D, Idaomar M (2008) Biological effects of essential oils—a review. Food Chem Toxicol 46:446–475

    Article  PubMed  CAS  Google Scholar 

  • Benedict MQ, Levine RS, Hawley WA, Lounibos LP (2007) Spread of the tiger: global risk of invasion by the mosquito Aedes albopictus. Vect Bor Zoon Dis 7:76–85

    Article  Google Scholar 

  • Benelli G, Flamini G, Canale A, Cioni PL, Conti B (2012a) Toxicity evaluation of different essential oil formulations against the Mediterranean Fruit Fly Ceratitis capitata (Wiedemann) (Diptera Tephritidae). Crop Protect 42:223–229

    Article  CAS  Google Scholar 

  • Benelli G, Flamini G, Canale A, Molfetta I, Cioni PL, Conti B (2012b) Repellence of Hyptis suaveolens L. (Lamiaceae) whole essential oil and major constituents against adults of the granary weevil Sitophilus granarius (L.) (Coleoptera: Dryophthoridae). Bull Insectol 65:177–183

    Google Scholar 

  • Bilal H, Akram W, Din S, Khan IA, Hassan SA, Arshad M (2012) Larvicidal activity of selected plant extracts against Aedes albopictus Skuse (Diptera: Culicidae). African Entomol 20:8–12

    Article  Google Scholar 

  • Caminade C, Medlock JM, Ducheyne E, McIntryre KM, Leach S, Baylis M, Morse A (2012) Suitability of European climate for the Asian tiger mosquito Aedes albopictus: recent trends and future scenarios. J R Soc Interface 9:2708–2717

    Article  PubMed  Google Scholar 

  • Chantraine JM, Laurent D, Ballivian C, Saavedra G, Ibanez R, Vilaseca A (1998) Insecticidal activity of essential oils on Aedes aegypti larvae. Phytother Res 12:350–354

    Article  CAS  Google Scholar 

  • Chung IM, Ahmad A, Kim SJ, Naik PM, Nagella P (2012) Composition of the essential oil constituents from leaves and stems of Korean Coriandrum sativum and their immunotoxicity activity on the Aedes aegypti L. Immunopharmacol Immunotoxicol 34:152–156

    Article  PubMed  CAS  Google Scholar 

  • Consoli RAGB, Mendes NM, Pereira JP, Santos BS, Lamounier MA (1989) Influence of several plant extracts on the oviposition behaviour of Aedes fluviatilis (Lutz) (Diptera: Culicidae) in the laboratory. Mem Ist Oswaldo Cruz 84:47–51

    Article  Google Scholar 

  • Conti B, Canale A, Bertoli A, Gozzini F, Pistelli L (2010) Essential oil composition and larvicidal activity of six Mediterranean aromatic plants against the mosquito Aedes albopictus (Diptera: Culicidae). Parasitol Res 107:1455–1462

    Article  PubMed  Google Scholar 

  • Conti B, Benelli G, Flamini G, Cioni PL, Profeti R, Ceccarini L, Macchia M, Canale A (2012a) Larvicidal and repellent activity of Hyptis suaveolens (Lamiaceae) essential oil against the mosquito Aedes albopictus Skuse (Diptera: Culicidae). Parasitol Res 110:2013–2021

    Article  PubMed  Google Scholar 

  • Conti B, Benelli G, Leonardi M, Afifi UF, Cervelli C, Profeti R, Pistelli L, Canale A (2012b) Repellent effect of Salvia dorisiana, S. longifolia and S. sclarea (Lamiaceae) essential oils against the mosquito Aedes albopictus Skuse (Diptera: Culicidae). Parasitol Res 111:291–299

    Article  PubMed  Google Scholar 

  • Conti B, Leonardi M, Pistelli L, Profeti R, Ouerghemmi I, Benelli G (2012c) Larvicidal and repellent activity of essential oils from wild and cultivated Ruta chalepensis L. (Rutaceae) against Aedes albopictus Skuse (Diptera: Culicidae), an arbovirus vector. Parasitol Res. doi:10.1007/s00436-012-3221-2

  • Davies NW (1990) Gas chromatographic retention indices of monoterpenes and sesquiterpenes on methyl silicon and carbowax 20M phases. J Chromatogr 503:1–24

    Article  CAS  Google Scholar 

  • Elango G, Rahuman AA, Kamaraj C, Bagavan A, Zahir AA (2011) Efficacy of medicinal plant extracts against malarial vector, Anopheles subpictus Grassi. Parasitol Res 108:1437–1445

    Article  PubMed  Google Scholar 

  • Evergetis E, Michaelakis A, Haroutounian SA (2012) Essential oils of Umbelliferae (Apiaceae) family taxa as emerging potent agents for mosquito control. In: Larramendy ML, Soloneski S (eds) Integrated pest management and pest control—current and future tactics. Janeza Trdine, Croatia, pp 613–638

    Google Scholar 

  • Fichi GL, Flamini G, Giovannelli F, Otranto D, Perrucci S (2007a) Efficacy of an essential oil of Eugenia caryophyllata against Psoroptes cuniculi. Exper Parasitol 115:168–172

    Article  CAS  Google Scholar 

  • Fichi GL, Flamini G, Zaralli LJ, Perrucci S (2007b) Efficacy of an essential oil of Cinnamomum zeylanicum against Psoroptes cuniculi. Phytomedicine 14:227–231

    Article  PubMed  CAS  Google Scholar 

  • Fradin MS, Day JF (2002) Comparative efficacy of insect repellents against mosquito bites. New Engl J Med 347:13–18

    Article  PubMed  CAS  Google Scholar 

  • Gleiser RM, Bonino MA, Zygadlo JA (2011) Repellence of essential oils of aromatic plants growing in Argentina against Aedes aegypti. Parasitol Res 108:69–78

    Article  PubMed  Google Scholar 

  • Govindarajan M, Sivakumar R (2012) Adulticidal and repellent properties of indigenous plant extracts against Culex quinquefasciatus and Aedes aegypti (Diptera: Culicidae). Parasitol Res 110:1607–1620

    Article  PubMed  Google Scholar 

  • Govindarajan M, Mathivanan T, Elumalai K, Krishnappa K, Anandan A (2011) Mosquito larvicidal, ovicidal, and repellent properties of botanical extracts against Anopheles stephensi, Aedes aegypti, and Culex quinquefasciatus (Diptera: Culicidae). Parasitol Res 109:353–367

    Article  PubMed  CAS  Google Scholar 

  • Hafeez F, Akram W, Shaalan EA (2011) Mosquito larvicidal activity of citrus limonoids against Aedes albopictus. Parasitol Res 109:221–229

    Article  PubMed  Google Scholar 

  • Hwang YS, Wu KH, Kumamoto J, Axelrod H, Mulla MS (1985) Isolation and identification of mosquito repellents in Artemisia vulgaris. J Chem Ecol 11:1297–1306

    Article  CAS  Google Scholar 

  • Jennings W, Shibamoto T (1980) Qualitative analysis of flavour and fragrance volatiles by glass capillary chromatography. Academic, New York

    Google Scholar 

  • Kamaraj C, Rahuman AA, Bagavan A, Elango G, Zahir AA, Santhoshkumar T (2011) Larvicidal and repellent activity of medicinal plant extracts from Eastern Ghats of South India against malaria and filariasis vectors. Asian Pacif J Tropic Med 2011:698–705

    Article  Google Scholar 

  • Kamsuk K, Choochote W, Chaithong U, Jitpakdi A, Tippawangkosol P, Riyong D, Pitasawat B (2007) Effectiveness of Zanthoxylum piperitum-derived essential oil as an alternative repellent under laboratory and field application. Parasitol Res 100:339–345

    Article  PubMed  CAS  Google Scholar 

  • Kang SH, Kim MK, Seo DK, Noh DJ, Yang JO, Yoon C, Kim GH (2009) Comparative repellency of essential oils against Culex pipiens pallens (Diptera: Culicidae). J Korean Appl Biol Soc 52:353–359

    Article  CAS  Google Scholar 

  • Kim SI, Park C, Ohh MH, Cho HC, Ahn YJ (2003) Contact and fumigant activities of aromatic plant extracts and essential oils against Lasioderma serricorne (Coleoptera: Anobiidae). J Stor Prod Res 39:11–19

    Article  CAS  Google Scholar 

  • Klun JA, Khrimian A, Debboun M (2006) Repellent and deterrent effects of SS220, Picaridin, and Deet suppress human blood feeding by Aedes aegypti, Anopheles stephensi, and Phlebotomus papatasi. J Med Entomol 43:34–39

    Article  PubMed  CAS  Google Scholar 

  • Knio KM, Usta J, Dagher S, Zournajian H, Kreydiyyeha S (2008) Larvicidal activity of essential oils extracted from commonly used herbs in Lebanon against the seaside mosquito, Ochlerotatus caspius. Bioresur Technol 99:763–768

    Article  CAS  Google Scholar 

  • Koliopoulos G, Pitarokili D, Kioulos E, Michaelakis A, Tzakou O (2010) Chemical composition and larvicidal evaluation of Mentha, Salvia, and Melissa essential oils against the West Nile virus mosquito Culex pipiens. Parasitol Res 107:327–335

    Article  PubMed  Google Scholar 

  • Kwon JH, Ahn YJ (2002) Acaricidal activity of butylidenephthalide identified in Cnidium officinale rhizome against Dermatophagoides farinae and Dermatophagoides pteronyssinus (Acari: Pyroglyphidae). J Agric Food Chem 50:4479–4483

    Article  PubMed  CAS  Google Scholar 

  • Lamiri A, Lhaloui S, Benjilali B, Berrada M (2001) Insecticidal effects of essential oils against Hessian fly, Mayetiola destructor (Say). Field Crops Res 71:9–15

    Article  Google Scholar 

  • Lapied B, Pennetier C, Apaire-Marchais V, Licznar P, Corbel V (2009) Innovative applications for insect viruses: towards insecticide sensitization. Trends Biotechnol 4:190–198

    Article  Google Scholar 

  • Massada Y (1976) Analysis of essential oils by gas chromatography and mass spectrometry. Wiley, New York

    Google Scholar 

  • Matasyoh JC, Maiyo ZC, Ngure RM, Chepkorir R (2009) Chemical composition and antimicrobial activity of the essential oil of Coriandrum sativum. Food Chem 113:526–529

    Article  CAS  Google Scholar 

  • Mathew N, Anitha MG, Bala TSL, Sivakumar SM, Narmadha R, Kalyanasundaram M (2009) Larvicidal activity of Saraca indica, Nyctanthes arbor-tristis and Clitoria ternatea extracts against three mosquito vector species. Parasitol Res 104:1017–1025

    Article  PubMed  Google Scholar 

  • Msaada K, Hosni K, Taarit MB, Thouraya C, Kchouk ME, Marzouk B (2007) Changes on essential oil composition of coriander (Coriandrum sativum L.) fruits during three stages of maturity. Food Chem 102:1131–1134

    Article  CAS  Google Scholar 

  • Nagella P, Kim MY, Ahmad A, Thiruvengadam M, Chung IM (2012) Chemical constituents, larvicidal effects and antioxidant activity of petroleum ether extract from seeds of Coriandrum sativum L. J Medicin Plant Res 6:2948–2954

    CAS  Google Scholar 

  • Noudjou F, Kouninki H, Ngamo LST, Maponmestsem PM, Ngassoum M, Hance T, Haubruge E, Malaisse F, Marlier M, Lognay GC (2007) Effect of site location and collecting period on the chemical composition of Hyptis spicigera Lam. an insecticidal essential oil from North Cameroon. J Essent Oil Res 19:597–601

    Article  CAS  Google Scholar 

  • Paupy C, Delatte H, Bagny L, Corbel V, Fontenille D (2009) Aedes albopictus, an arbovirus vector: from the darkness to light. Microb Infect 11:1177–1185

    Article  CAS  Google Scholar 

  • Pushpanathan T, Jebanesan A, Govindarajan M (2006) Larvicidal, ovicidal and repellent activities of Cymbopogan citrates Stapf (Graminae) essential oil against the filarial mosquito Culex quinquefasciatus (Say) (Diptera: Culicidae). Tropical Biomed 23:208–212

    CAS  Google Scholar 

  • Rajkumar S, Jebanesan A (2005) Repellency of volatile oils from Moschosma polystachyum and Solanum xanthocarpum against filarial vector Culex quinquefasciatus Say. Tropical Biomed 22:139–142

    CAS  Google Scholar 

  • Robert LL, Olson JK (1989) Susceptibility of female Aedes albopictus from Texas to commonly used adulticides. J Am Mosq Control Assoc 5:251–253

    PubMed  CAS  Google Scholar 

  • Sedaghat MM, Dehkordi AS, Abai MR, Khanavi M, Mohtarami F, Salim Abadi Y, Rafi F, Vatandoost H (2011) Larvicidal activity of essential oils of Apiaceae plants against malaria vector, Anopheles stephensi. Iran J Arthropod-Borne Dis 5:51–59

    PubMed  Google Scholar 

  • Severini C, Romi R, Marinucci M, Rajmond M (1993) Mechanism of insecticide resistance in field populations of Culex pipiens from Italy. J Am Mosq Control Assoc 9:164–168

    PubMed  CAS  Google Scholar 

  • Stenhagen E, Abrahamson S, McLafferty FW (1974) Registry of mass spectral data. Wiley, New York

    Google Scholar 

  • Sudakin DL, Trevathan WR (2003) Deet: a review and update of safety and risk in the general population. J Toxicol Clin Toxicol 41:831

    Article  PubMed  CAS  Google Scholar 

  • Swigar AA, Silverstein RM (1981) Monoterpenes. Aldrich Chem Comp, Milwaukee

    Google Scholar 

  • Tsukamoto T, Ishikawa Y, Miyazawa M (2005) Larvicidal and adulticidal activity of alkylphthalide derivatives from rhizome of Cnidium officinale against Drosophila melanogaster. J Agric Food Chem 53:5549–5553

    Article  PubMed  CAS  Google Scholar 

  • Tunc I, Berger BM, Erler F, Dagh F (2000) Ovicidal activity of essential oil from five plants against two stored-product insects. J Stor Prod Res 36:161–168

    Article  CAS  Google Scholar 

  • WHO (1981) Instruction for determining the susceptibility or resistance of mosquito larvae to insecticide. WHO/VBC/81.807. Control of tropical diseases. World Health Organization, Geneva

    Google Scholar 

  • WHO (2009) Guidelines for efficacy testing of mosquito repellents for human skin. WHO/HTM/NTD/WHOPES/2009.4. Control of neglected tropical diseases. World Health Organization, Geneva

    Google Scholar 

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Acknowledgments

We would like to thank Dr. Angelo Canale (University of Pisa) for his insightful critical comments on an earlier version of the manuscript, Prof. Mario Macchia (University of Pisa) for providing the C. sativum fruits; Dr. Helen Romito (Sant’Anna School of Advanced Studies, Pisa) for proofreading the article; Giulia Giunti, Raffaele Profeti, and Paolo Giannotti (University of Pisa) for their kind assistance during experiments and the ten patient volunteers.

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Authors and Affiliations

  1. Entomology Section—Department of Agriculture, Food and Environment, University of Pisa, Via del Borghetto 80, 56124, Pisa, Italy

    Giovanni Benelli, Giulia Fiore & Barbara Conti

  2. Department of Pharmacy, University of Pisa, Via Bonanno 33, 56126, Pisa, Italy

    Guido Flamini & Pier Luigi Cioni

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  1. Giovanni Benelli
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  2. Guido Flamini
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  3. Giulia Fiore
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  4. Pier Luigi Cioni
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  5. Barbara Conti
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Correspondence to Barbara Conti.

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Benelli, G., Flamini, G., Fiore, G. et al. Larvicidal and repellent activity of the essential oil of Coriandrum sativum L. (Apiaceae) fruits against the filariasis vector Aedes albopictus Skuse (Diptera: Culicidae). Parasitol Res 112, 1155–1161 (2013). https://doi.org/10.1007/s00436-012-3246-6

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