Abstract
Tropical diseases present significant challenges to global health, particularly in resource-limited regions. Early and accurate detection of these diseases is vital for effective management and control. In recent years, metallic-based LSPR sensors have emerged as promising diagnostic tools for sensitive and rapid detection of tropical diseases. This comprehensive review aims to provide an in-depth analysis of the current state of research on metallic-based LSPR sensors for the detection of various tropical diseases. In this study, we focused on the connection between neglected tropical diseases (NTDs) and its risk using metallic-based LSPR sensors to identify potential inflammatory biomarkers. We conducted a literature search using PubMed, Web of Science, and Google Scholar. Only published materials written in English were considered, resulting in the identification of \(\sim\) 220 articles. After a comprehensive evaluation, we selected 35 relevant ones. Our analysis revealed 35 links to neglected tropical diseases, providing valuable insights into their relationship using metallic-based LSPR sensors. Moreover, we explore the potential of metallic-based LSPR sensors in point-of-care testing and their integration with emerging technologies such as microfluidics and smartphone-based diagnostics. This review underscores the need for continued research efforts to develop affordable, sensitive, and user-friendly metallic-based LSPR sensors for early detection and surveillance of tropical diseases.
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Data Availability
The data is available on request from the corresponding author.
References
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This work was funded by CNPq (INCT-INTERAS 406761/2022-1), INCT-INFO (465763/2014-6); Sisfoton (440228/2021-2); PQ (314517/2021-9); CAPES Finance code 001 and FAPESP (17/50332-0) and FAPESP (21/00633-0).
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Farooq, S., Zezell, D.M. Advances in Metallic-Based Localized Surface Plasmon Sensors for Enhanced Tropical Disease Detection: A Comprehensive Review. Plasmonics (2023). https://doi.org/10.1007/s11468-023-02109-z
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DOI: https://doi.org/10.1007/s11468-023-02109-z