Abstract
An understanding of the role of inherited cancer predisposition syndromes in pediatric tumor diagnoses continues to develop as more information is learned through the application of genomic technology. Identifying patients and their relatives at an increased risk for developing cancer is an important step in the care of this patient population. The purpose of this review is to highlight various tumor types that arise in the pediatric population and the cancer predisposition syndromes associated with those tumors. The review serves as a guide for recognizing genes and conditions to consider when a pediatric cancer referral presents to the genetics clinic.
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Ms. Knoth is a salaried employee of Myriad Genetic Laboratories, Inc. and holds MYGN stock. There are no additional conflicts of interest.
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Scollon, S., Anglin, A.K., Thomas, M. et al. A Comprehensive Review of Pediatric Tumors and Associated Cancer Predisposition Syndromes. J Genet Counsel 26, 387–434 (2017). https://doi.org/10.1007/s10897-017-0077-8
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DOI: https://doi.org/10.1007/s10897-017-0077-8