Skip to main content
SpringerLink
Log in

Analysis of Fatigue Strength and Reliability of Lower Limb Arterial Stent at Different Vascular Stenosis Rates and Stent-to-Artery Ratios

  • Review
  • Published:
Annals of Biomedical Engineering Aims and scope Submit manuscript

Abstract

In order to study the influence of different vascular stenosis rates and stent-to-artery ratios on the fatigue strength and reliability of lower limb arterial stents, numerical simulation was conducted for the fatigue strength of complete SE stents under pulsating loads using a finite element method. Then, fracture mechanics and conditional probability theory were adopted for mathematical modeling, whereby analyzing the crack growth rate and reliability with stents of different thickness (0.12, 0.15, and 0.18 mm) at different vascular stenosis rates (30, 50, and 70%) and stent-to-artery ratios (80, 85, and 90%). The study found: all three stents of different thickness failed to meet 10-year service life at three vascular stenosis rates; all three stents of different thickness met 10-year service life at three stent-to-artery ratios. With increased vascular stenosis rate, the elastic strain of stents was increased, while the fatigue strength was decreased; with increased stent-to-artery ratio, the elastic strain of the stent was increased, while the reliability of the stent was reduced. After the stent with an initial crack was implanted into the vessel, the crack length underwent non-linear growth with increased pulsating cyclic loads. When the pulsating load reached 3 × 108, the growth rate of the crack on the stent surface increased exponentially, leading to a rapid decrease in reliability. Vascular stenosis rate, stent release ratio, and support thickness have significant effects on crack length propagation rate and reliability. Determining the influence of vascular stenosis rate and stent-to-artery ratio on the fatigue strength and reliability of stents provides a valuable reference for evaluating the fracture failure rate and safety of stents.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

FIGURE 1
FIGURE 2
FIGURE 3
FIGURE 4
FIGURE 5
FIGURE 6
FIGURE 7
FIGURE 8

Similar content being viewed by others

References

  1. Beebe, H. G. Lessons learned from aortic aneurysm stent graft failure: observations from several perspectives. Semin. Vasc. Surg. 16:129–138, 2003.

    Article  PubMed  Google Scholar 

  2. Bernini, M., M. Colombo, and C. Dunlop. Oversizing of self-expanding nitinol vascular stents—a biomechanical investigation in the superficial femoral artery. J. Mech. Behav. Biomed. Mater.132:105259, 2022.

    Article  CAS  PubMed  Google Scholar 

  3. Cardini, F., E. Zio, and D. Avram. Model-based Monte Carlo state estimation for condition-based component replacement. Reliab. Eng. Syst. Saf. 94:752–758, 2009.

    Article  Google Scholar 

  4. Cunnane, E. M., J. J. Mulvihill, H. E. Barrett, et al. Mechanical, biological and structural characterization of human atherosclerotic femoral plaque tissue. Acta Biomater. 11:295–303, 2015.

    Article  CAS  PubMed  Google Scholar 

  5. Daly, S., A. Miller, G. Ravichandran, and K. Bhattacharya. An experimental investigation of crack initiation in thin sheets of nitinol. Acta Mater. 55:6322–30, 2007.

    Article  CAS  Google Scholar 

  6. De Bock, S., F. Iannaccone, G. De Santis, et al. Virtual evaluation of stent graft deployment: a validated modeling and simulation study. J. Mech. Behav. Biomed. Mater. 13:129–139, 2012.

    Article  PubMed  Google Scholar 

  7. Duerig, T. W., A. R. Pelton, and D. Stockel. An overview of nitinol medical applications. Mater. Sci. Eng. A. 273:149–160, 1999.

    Article  Google Scholar 

  8. Feng, H. Q., Z. Y. Hu, X. D. Jiang, et al. Research on elastic and plastic deformation of CoCr alloy used for coronary stents. J. Plast. Eng. 19:108–112, 2012.

    CAS  Google Scholar 

  9. Gasser, T. C., R. W. Ogden, and G. A. Holzapfel. Hyperelastic modelling of arterial layers with distributed collagen fibre orientations. J. R. Soc. Interface. 3:15–35, 2006.

    Article  PubMed  Google Scholar 

  10. Gökgöl, C., N. Diehm, and P. Büchler. Numerical modeling of nitinol stent oversizing in arteries with clinically relevant levels of peripheral arterial disease: the influence of plaque type on the outcomes of endovascular therapy. Ann. Biomed. Eng. 56:1420–1433, 2017.

    Article  Google Scholar 

  11. Gökgöl, C., N. Diehm, F. R. Nezami, et al. Nitinol stent oversizing in patients undergoing popliteal artery revascularization: a finite element study. Ann. Biomed. Eng. 43:2868–2880, 2015.

    Article  PubMed  Google Scholar 

  12. He, R., L. G. Zhao, and V. V. Silberschmidt. A computational study of fatigue resistance of nitinol stents subjected to walk-induced femoropopliteal artery motion. J. Biomech.118:110295, 2021.

    Article  CAS  PubMed  Google Scholar 

  13. Holzapfel, G. A., M. Stadler, and C. A. J. Schulze-Bauer. A layer-specific three-dimensional model for the simulation of balloon angioplasty using magnetic resonance imaging and mechanical testing. Ann. Biomed. Eng. 30:753–767, 2002.

    Article  PubMed  Google Scholar 

  14. Jimenez-Navarro, M. F., F. Lopez-Jimenez, G. Barsness, et al. Long-term prognosis of complete percutaneous coronary revascularisation in patients with diabetes with multivessel disease. Heart. 101:1233–1239, 2015.

    Article  PubMed  Google Scholar 

  15. Keedy, E., and Q. Feng. A physics-of-failure based reliability and maintenance modeling framework for stent deployment and operation. Reliab. Eng. Syst. Saf. 103:94–101, 2012.

    Article  Google Scholar 

  16. Lei, L., X. Qi, S. Li, et al. Finite element analysis for fatigue behaviour of a self-expanding nitinol peripheral stent under physiological biomechanical conditions. Comput. Biol. Med. 104:205–214, 2019.

    Article  PubMed  Google Scholar 

  17. Li, Z., H. Feng, and W. Yan. Fatigue strength of intracranial artery stents. J. Med. Biomech. 33:442–446, 2018.

    Google Scholar 

  18. Marines-Garcia, I., P. C. Paris, H. Tada, and C. Bathias. Fatigue crack growth from small to long cracks in very-high-cycle fatigue with surface and internal “fish-eye” failures for ferrite-perlitic low carbon steel SAE 8620. Mater. Sci. Eng. A. 468:120–128, 2007.

    Article  Google Scholar 

  19. Marrey, R., R. Burgermeister, and R. O. Grishaber. Fatigue and life prediction for cobalt-chromium stents: a fracture mechanics analysis. Biomaterials. 27:1988–2000, 2006.

    Article  CAS  PubMed  Google Scholar 

  20. Martin, D., and F. Boyle. Finite element analysis of balloon-expandable coronary stent deployment: influence of angioplasty balloon configuration. Int. J. Numer. Method Biomed. Eng. 29:1161–1175, 2013.

    Article  PubMed  Google Scholar 

  21. Members, W. G., D. Mozaffarian, E. J. Benjamin, et al. Executive summary: heart disease and stroke statistics—2016 update: a report from the American Heart Association. Circulation. 127:143–152, 2016.

    Google Scholar 

  22. Morlacchi, S., G. Pennati, L. Petrini, et al. Influence of plaque calcifications on coronary stent fracture: a numerical fatigue life analysis including cardiac wall movement. J. Biomech. 47:899–907, 2014.

    Article  PubMed  Google Scholar 

  23. Pelton, A., X. Gong, and T. Duerig. Fatigue testing of diamond-shaped specimens. Med. Devices Mater. 2:199–204, 2003.

    Google Scholar 

  24. Peng, H., Q. Feng, and D. W. Coit. Reliability modeling for MEMS devices subjected to multiple dependent competing failure processes. Proc. Ind. Eng. Res. Conf. 64:932–948, 2012.

    Google Scholar 

  25. Riepe, G., C. Heintz, E. Kaiser, et al. What can we learn from explanted endovascular devices. Eur. J. Vasc. Endovasc. Surg. 24:117–122, 2002.

    Article  CAS  PubMed  Google Scholar 

  26. Robertson, S. W., and R. O. Ritchie. In vitro fatigue–crack growth and fracture toughness behavior of thin-walled superelastic nitinol tube for endovascular stents: a basis for defining the effect of crack-like defects. Biomaterials. 28:700–709, 2007.

    Article  CAS  PubMed  Google Scholar 

  27. Robertson, S. W., and R. O. Ritchie. A fracture-mechanics-based approach to fracture control in biomedical devices manufactured from superelastic nitinol tube. J. Biomed. Mater. Res. B. 84:26–33, 2007.

    Google Scholar 

  28. Sachs, N. W. Understanding the surface features of fatigue fractures: how they describe the failure cause and the failure history. J. Fail. Anal. Prev. 5:11–15, 2005.

    Article  Google Scholar 

  29. Shishehbor, M. H., and M. R. Jaff. Percutaneous therapies for peripheral artery disease. Circulation. 134:2008–2027, 2016.

    Article  CAS  PubMed  Google Scholar 

  30. Song, J. Research on the Expansion and Fatigue Properties of Medical Stents in Narrow Tapered Blood Vessels. Zhenjiang: Jiangsu University, 2018.

    Google Scholar 

  31. Stents, I., and H. Services. Guidance for Industry an FDA Staff Non-Clinical Engineering Tests and Recommended Labeling for Intravascular Stentsand Associated Delivery Systems, 2010.

  32. Wang, J. Research on Prediction of Ultra-high Cycle Fatigue Life and the Judgment of Re-manufacturability of Blade Material FV520B-1 Based on Fatigue Damage. Dalian: Dalian University of Technology, 2019.

    Google Scholar 

  33. Wang, Y., and H. Pham. Imperfect preventive maintenance policies for two-process cumulative damage model of degradation and random shocks. Int. J. Syst. Assur. Eng. Manag. 2:66–77, 2011.

    Article  CAS  Google Scholar 

  34. Xu, J. Research on the Mechanical Mechanism of Coronary Stent Fracture. Chengdu: Southwest Jiaotong University, 2018.

    Google Scholar 

Download references

Acknowledgments

The work was supported by the National Natural Science Foundation of China (12162026), by the Inner Mongolia Science and Technology Plan Project (2020GG0024), and the Natural Science Foundation of Inner Mongolia (2021LHMS05001).

Conflict of interest

The authors declare that there is no potential conflict of interest with respect to the research, authorship, and/or publication of this article.

Author information

Authors and Affiliations

  1. School of Mechanical Engineering, Inner Mongolia University of Technology, Hohhot, 010051, Inner Mongolian Autonomous Region, People’s Republic of China

    Shuangquan Ma & Haiquan Feng

  2. School of Materials Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing, 210000, Jiangsu Province, People’s Republic of China

    Haoxiang Feng

  3. School of Materials Science and Technology, Inner Mongolia University of Technology, Hohhot, 010051, Inner Mongolian Autonomous Region, People’s Republic of China

    Juan Su

Authors
  1. Shuangquan Ma
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Haiquan Feng
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Haoxiang Feng
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Juan Su
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Haiquan Feng or Juan Su.

Additional information

Associate Editor Stefan M. Duma oversaw the review of this article.

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Ma, S., Feng, H., Feng, H. et al. Analysis of Fatigue Strength and Reliability of Lower Limb Arterial Stent at Different Vascular Stenosis Rates and Stent-to-Artery Ratios. Ann Biomed Eng 51, 1136–1146 (2023). https://doi.org/10.1007/s10439-023-03165-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10439-023-03165-6

Keywords

Search

Navigation