Abstract
This review (with 160 ref.) summarizes the progress that has been made in the methods for chemical or biochemical sensing of hypoxanthine and xanthine, which are produced as part of purine metabolism and are precursors of uric acid. An introduction discusses the importance of hypoxanthine and xanthine as analytes due to their significance in the clinical and food science, together with the conventional methods of analysis. A large section covers methods for the electrochemical hypoxanthine and xanthine sensing. It is divided into subsections according to the nanomaterials used including carbon nanomaterials, meal oxide nanoparticles, metal organic frameworks, conductive polymers, and bio-nanocomposites. A further large section covers optical methods for hypoxanthine and xanthine sensing, with subsections on nanomaterials including carbon nanomaterials, nanosheets, nanoclusters, nanoparticles, and their bio-nanocomposites. A concluding section summarizes the current status, addresses current challenges, and discusses future perspectives.
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References
Cao H, Pauff JM, Hille R (2010) Substrate orientation and catalytic specificity in the action of xanthine oxidase: the sequential hydroxylation of hypoxanthine to uric acid. J Biol Chem 285(36):28044–28053. https://doi.org/10.1074/jbc.M110.128561
Trager WF (2007) 5.05 - principles of drug metabolism 1: redox reactions. In: Taylor JB, Triggle DJ (eds) Comprehensive medicinal chemistry II. Elsevier, Oxford, pp 87–132. https://doi.org/10.1016/B0-08-045044-X/00119-X
Chen C, Lü J-M, Yao Q (2016) Hyperuricemia-related diseases and xanthine oxidoreductase (XOR) inhibitors: An overview. Med Sci Monit 22:2501–2512. https://doi.org/10.12659/msm.899852
Battelli MG, Polito L, Bortolotti M, Bolognesi A (2016) Xanthine oxidoreductase-derived reactive species: physiological and pathological effects. Oxidative Med Cell Longev 2016:8. https://doi.org/10.1155/2016/3527579
Murphy MP, Holmgren A, Larsson N-G, Halliwell B, Chang CJ, Kalyanaraman B, Rhee SG, Thornalley PJ, Partridge L, Gems D, Nyström T, Belousov V, Schumacker PT, Winterbourn CC (2011) Unraveling the biological roles of reactive oxygen species. Cell Metab 13(4):361–366. https://doi.org/10.1016/j.cmet.2011.03.010
Lawal AT, Adeloju SB (2012) Progress and recent advances in fabrication and utilization of hypoxanthine biosensors for meat and fish quality assessment: a review. Talanta 100:217–228. https://doi.org/10.1016/j.talanta.2012.07.085
Drulovic J, Dujmovic I, Stojsavljevic N, Mesaros S, Andjelkovic S, Miljkovic D, Peric V, Dragutinovic G, Marinkovic J, Levic Z, Mostarica Stojkovic M (2001) Uric acid levels in sera from patients with multiple sclerosis. J Neurol 248(2):121–126
Schroder K, Tschopp J (2010) The Inflammasomes. Cell 140(6):821–832. https://doi.org/10.1016/j.cell.2010.01.040
Kushiyama A, Nakatsu Y, Matsunaga Y, Yamamotoya T, Mori K, Ueda K, Inoue Y, Sakoda H, Fujishiro M, Ono H, Asano T (2016) Role of uric acid metabolism-related inflammation in the pathogenesis of metabolic syndrome components such as atherosclerosis and nonalcoholic steatohepatitis. Mediat Inflamm 2016:8603164–8603164. https://doi.org/10.1155/2016/8603164
Dussol B, Ceballos-Picot I, Aral B, Castera V, Philip N, Berland Y (2004) Kelley–Seegmiller syndrome due to a new variant of the hypoxanthine–guanine phosphoribosyltransferase (I136T) encoding gene (HPRT Marseille). J Inherit Metab Dis 27(4):543–545. https://doi.org/10.1023/B:BOLI.0000037399.72152.a9
Tohgi H, Abe T, Takahashi S, Kikuchi T (1993) The urate and xanthine concentrations in the cerebrospinal fluid in patients with vascular dementia of the Binswanger type, Alzheimer type dementia, and Parkinson's disease. J Neural Transm Park Dis Dement Sect 6(2):119–126. https://doi.org/10.1007/bf02261005
Omokawa A, Oguma M, Ueki S, Saga T, Hirokawa M (2018) Urine xanthine crystals in tumor lysis syndrome. Urology 120:e9–e10. https://doi.org/10.1016/j.urology.2018.07.009
Sahar FS, Steven CD (2015) Xanthinuria workup. Medscape. https://emedicine.medscape.com/article/984002-workup. Accessed 13 Oct 2015
Zhao J, Liang Q, Luo G, Wang Y, Zuo Y, Jiang M, Yu G, Zhang T (2005) Purine metabolites in gout and asymptomatic hyperuricemia: analysis by HPLC–electrospray tandem mass spectrometry. Clin Chem 51(9):1742–1744. https://doi.org/10.1373/clinchem.2004.040261
Gudbjörnsson B, Zak A, Niklasson F, Hällgren R (1991) Hypoxanthine, xanthine, and urate in synovial fluid from patients with inflammatory arthritides. Ann Rheum Dis 50(10):669–672. https://doi.org/10.1136/ard.50.10.669
Hira HS, Samal P, Kaur A, Kapoor S (2014) Plasma level of hypoxanthine/xanthine as markers of oxidative stress with different stages of obstructive sleep apnea syndrome. Ann Saudi Med 34(4):308–313. https://doi.org/10.5144/0256-4947.2014.308
Laing I, Brown JK, Harkness RA (1988) Clinical and biochemical assessments of damage due to perinatal asphyxia: a double blind trial of a quantitative method. J Clin Pathol 41(3):247–252. https://doi.org/10.1136/jcp.41.3.247
Si Y, Park JW, Jung S, Hwang G-S, Goh E, Lee HJ (2018) Layer-by-layer electrochemical biosensors configuring xanthine oxidase and carbon nanotubes/graphene complexes for hypoxanthine and uric acid in human serum solutions. Biosens Bioelectron 121:265–271. https://doi.org/10.1016/j.bios.2018.08.074
Dervisevic M, Custiuc E, Çevik E, Şenel M (2015) Construction of novel xanthine biosensor by using polymeric mediator/MWCNT nanocomposite layer for fish freshness detection. Food Chem 181:277–283. https://doi.org/10.1016/j.foodchem.2015.02.104
Pereira PM, Vicente AF (2013) Meat nutritional composition and nutritive role in the human diet. Meat Sci 93(3):586–592. https://doi.org/10.1016/j.meatsci.2012.09.018
Devi R, Narang J, Yadav S, Pundir CS (2012) Amperometric determination of xanthine in tea, coffee, and fish meat with graphite rod bound xanthine oxidase. J Anal Chem 67(3):273–277. https://doi.org/10.1134/s1061934812030045
Stratton CJ (1980) The xanthines: coffee, cola, cocoa, and tea. BYU Studies 20(4):371–388
Favrod-Coune T, Broers B (2015) Addiction to caffeine and other xanthines. In: el-Guebaly N, Carrà G, Galanter M (eds) Textbook of addiction treatment: international perspectives. Springer Milan, Milano, pp 437–453. https://doi.org/10.1007/978-88-470-5322-9_18
Li G, Liu F, Hao J, Liu C (2015) Determination of purines in beer by HPLC using a simple and rapid sample pretreatment. J Am Soc Brew Chem 73(2):137–142. https://doi.org/10.1094/ASBCJ-2015-0409-01
Fukuuchi T, Yasuda M, Inazawa K, Ota T, Yamaoka N, K-i M, Nakagomi K, Kaneko K (2013) A simple HPLC method for determining the purine content of beer and beer-like alcoholic beverages. Anal Sci 29(5):511–517. https://doi.org/10.2116/analsci.29.511
Kock R, Delvoux B, Greiling H (1993) A high-performance liquid chromatographic method for the determination of hypoxanthine, xanthine, uric acid and allantoin in serum. Eur J Clin Chem Clin Biochem 31(5):303–310
Burdett TC, Desjardins CA, Logan R, McFarland NR, Chen X, Schwarzschild MA (2013) Efficient determination of purine metabolites in brain tissue and serum by high-performance liquid chromatography with electrochemical and UV detection. Biomed Chromatogr 27(1):122–129. https://doi.org/10.1002/bmc.2760
Cooper N, Khosravan R, Erdmann C, Fiene J, Lee JW (2006) Quantification of uric acid, xanthine and hypoxanthine in human serum by HPLC for pharmacodynamic studies. J Chromatogr B Anal Technol Biomed Life Sci 837(1–2):1–10. https://doi.org/10.1016/j.jchromb.2006.02.060
Prker R, Snedden W, Watts RW (1969) The mass-spectrometirc identification of hypoxanthine and xanthine ('oxypurines') in skeletal musce from two patients with congenital xanthine oxidase deficiency (xanthinuria). Biochem J 115(1):103–108. https://doi.org/10.1042/bj1150103
Rashed MS, Saadallah AA, Rahbeeni Z, Eyaid W, Seidahmed MZ, Al-Shahwan S, Salih MA, Osman ME, Al-Amoudi M, Al-Ahaidib L, Jacob M (2005) Determination of urinary S-sulphocysteine, xanthine and hypoxanthine by liquid chromatography-electrospray tandem mass spectrometry. Biomed Chromatogr 19(3):223–230. https://doi.org/10.1002/bmc.439
Chen G, Chu Q, Zhang L, Ye J (2002) Separation of six purine bases by capillary electrophoresis with electrochemical detection. Anal Chim Acta 457(2):225–233. https://doi.org/10.1016/S0003-2670(02)00027-2
Pagliarussi RS, Freitas LAP, Bastos JK (2002) A quantitative method for the analysis of xanthine alkaloids in Paullinia cupana (guarana) by capillary column gas chromatography. J Sep Sci 25(5–6):371–374. https://doi.org/10.1002/1615-9314(20020401)25:5/6<371::aid-jssc371>3.0.co;2-9
Chalmers RA, Watts RWE (1968) An enzymatic spectrophotometric method for the determination of “oxypurines”(hypoxanthine plus xanthine) in urine and blood plasma. Analyst 93(1107):354–362. https://doi.org/10.1039/AN9689300354
Sahu PK, Ramisetti NR, Cecchi T, Swain S, Patro CS, Panda J (2018) An overview of experimental designs in HPLC method development and validation. J Pharm Biomed Anal 147:590–611. https://doi.org/10.1016/j.jpba.2017.05.006
Hecht ES, Oberg AL, Muddiman DC (2016) Optimizing mass spectrometry analyses: a tailored review on the utility of Design of Experiments. J Am Soc Mass Spectrom 27(5):767–785. https://doi.org/10.1007/s13361-016-1344-x
Orlandini S, Gotti R, Furlanetto S (2014) Multivariate optimization of capillary electrophoresis methods: a critical review. J Pharm Biomed Anal 87:290–307. https://doi.org/10.1016/j.jpba.2013.04.014
Voeten RLC, Ventouri IK, Haselberg R, Somsen GW (2018) Capillary electrophoresis: trends and recent advances. Anal Chem 90(3):1464–1481. https://doi.org/10.1021/acs.analchem.8b00015
Raj MA, John SA (2013) Simultaneous determination of uric acid, xanthine, hypoxanthine and caffeine in human blood serum and urine samples using electrochemically reduced graphene oxide modified electrode. Anal Chim Acta 771:14–20. https://doi.org/10.1016/j.aca.2013.02.017
Zhu D, Guo D, Zhang L, Tan L, Pang H, Ma H, Zhai M (2019) Non-enzymatic xanthine sensor of heteropolyacids doped ferrocene and reduced graphene oxide via one-step electrodeposition combined with layer-by-layer self-assembly technology. Sensors Actuators B Chem 281:893–904. https://doi.org/10.1016/j.snb.2018.10.151
Zhu D, Ma H, Pang H, Tan L, Jiao J, Chen T (2018) Facile fabrication of a non-enzymatic nanocomposite of heteropolyacids and CeO2@Pt alloy nanoparticles doped reduced graphene oxide and its application towards the simultaneous determination of xanthine and uric acid. Electrochim Acta 266:54–65. https://doi.org/10.1016/j.electacta.2018.01.185
Tang X, Liu Y, Hou H, You T (2011) A nonenzymatic sensor for xanthine based on electrospun carbon nanofibers modified electrode. Talanta 83(5):1410–1414. https://doi.org/10.1016/j.talanta.2010.11.019
Villalonga R, Díez P, Eguílaz M, Martínez P, Pingarrón JM (2012) Supramolecular immobilization of xanthine oxidase on electropolymerized matrix of functionalized hybrid gold nanoparticles/single-walled carbon nanotubes for the preparation of electrochemical biosensors. ACS Appl Mater Interfaces 4(8):4312–4319. https://doi.org/10.1021/am300983u
Zhang L, Li S, Xin J, Ma H, Pang H, Tan L, Wang X (2019) A non-enzymatic voltammetric xanthine sensor based on the use of platinum nanoparticles loaded with a metal-organic framework of type MIL-101(Cr). Application to simultaneous detection of dopamine, uric acid, xanthine and hypoxanthine. Microchim Acta 186(1):9. https://doi.org/10.1007/s00604-018-3128-4
Wen Y, Chang J, Xu L, Liao X, Bai L, Lan Y, Li M (2017) Simultaneous analysis of uric acid, xanthine and hypoxanthine using voltammetric sensor based on nanocomposite of palygorskite and nitrogen doped graphene. J Electroanal Chem 805:159–170. https://doi.org/10.1016/j.jelechem.2017.09.053
Rahman MM, Marwani HM, Algethami FK, Asiri AM (2017) Xanthine sensor development based on ZnO–CNT, ZnO–CB, ZnO–GO and ZnO nanoparticles: an electrochemical approach. New J Chem 41(14):6262–6271. https://doi.org/10.1039/C7NJ00278E
Ibrahim H, Temerk Y (2016) Sensitive electrochemical sensor for simultaneous determination of uric acid and xanthine in human biological fluids based on the nano-boron doped ceria modified glassy carbon paste electrode. J Electroanal Chem 780:176–186. https://doi.org/10.1016/j.jelechem.2016.09.016
Zhang F, Wang Z, Zhang Y, Zheng Z, Wang C, Du Y, Ye W (2012) Simultaneous electrochemical determination of uric acid, xanthine and hypoxanthine based on poly(l-arginine)/graphene composite film modified electrode. Talanta 93:320–325. https://doi.org/10.1016/j.talanta.2012.02.041
Lavanya N, Sekar C, Murugan R, Ravi G (2016) An ultrasensitive electrochemical sensor for simultaneous determination of xanthine, hypoxanthine and uric acid based on Co doped CeO2 nanoparticles. Mater Sci Eng C 65:278–286. https://doi.org/10.1016/j.msec.2016.04.033
Ibrahim H, Temerk Y (2016) A novel electrochemical sensor based on B doped CeO2 nanocubes modified glassy carbon microspheres paste electrode for individual and simultaneous determination of xanthine and hypoxanthine. Sensors Actuators B Chem 232:125–137. https://doi.org/10.1016/j.snb.2016.03.133
Thangaraj R, Kumar AS (2012) Graphitized mesoporous carbon modified glassy carbon electrode for selective sensing of xanthine, hypoxanthine and uric acid. Anal Methods 4(7):2162–2171. https://doi.org/10.1039/C2AY25029B
Xu G-B, Cui J-M, Liu H, Gao G-G, Qiu Y-F, Zhang S-M, Wu D-M (2015) Highly selective detection of cellular guanine and xanthine by polyoxometalate modified 3D graphene foam. Electrochim Acta 168:32–40. https://doi.org/10.1016/j.electacta.2015.03.222
Yin D, Liu J, Bo X, Li M, Guo L (2017) Porphyrinic metal-organic framework/macroporous carbon composites for electrocatalytic applications. Electrochim Acta 247:41–49. https://doi.org/10.1016/j.electacta.2017.06.176
Li X, Li C, Wu C, Wu K (2019) Strategy for highly sensitive electrochemical sensing: in situ coupling of a metal–organic framework with ball-mill-exfoliated graphene. Anal Chem 91(9):6043–6050. https://doi.org/10.1021/acs.analchem.9b00556
Luo A, Lian Q, An Z, Li Z, Guo Y, Zhang D, Xue Z, Zhou X, Lu X (2015) Simultaneous determination of uric acid, xanthine and hypoxanthine based on sulfonic groups functionalized nitrogen-doped graphene. J Electroanal Chem 756:22–29. https://doi.org/10.1016/j.jelechem.2015.08.008
Thandavan K, Gandhi S, Sethuraman S, Rayappan JBB, Krishnan UM (2013) Development of electrochemical biosensor with nano-interface for xanthine sensing – a novel approach for fish freshness estimation. Food Chem 139(1):963–969. https://doi.org/10.1016/j.foodchem.2013.02.008
Devi R, Thakur M, Pundir CS (2011) Construction and application of an amperometric xanthine biosensor based on zinc oxide nanoparticles–polypyrrole composite film. Biosens Bioelectron 26(8):3420–3426. https://doi.org/10.1016/j.bios.2011.01.014
Dalkiran B, Kaçar C, Erden PE, Kiliç E (2014) Amperometric xanthine biosensors based on chitosan-Co3O4-multiwall carbon nanotube modified glassy carbon electrode. Sensors Actuators B Chem 200:83–91. https://doi.org/10.1016/j.snb.2014.04.025
Dervisevic M, Dervisevic E, Çevik E, Şenel M (2017) Novel electrochemical xanthine biosensor based on chitosan–polypyrrole–gold nanoparticles hybrid bio-nanocomposite platform. J Food Drug Anal 25(3):510–519. https://doi.org/10.1016/j.jfda.2016.12.005
Dervisevic M, Dervisevic E, Azak H, Çevik E, Şenel M, Yildiz HB (2016) Novel amperometric xanthine biosensor based on xanthine oxidase immobilized on electrochemically polymerized 10-[4H-dithieno(3,2-b:2′,3′-d)pyrrole-4-yl]decane-1-amine film. Sensors Actuators B Chem 225:181–187. https://doi.org/10.1016/j.snb.2015.11.043
Dervisevic M, Custiuc E, Çevik E, Durmus Z, Şenel M, Durmus A (2015) Electrochemical biosensor based on REGO/Fe3O4 bionanocomposite interface for xanthine detection in fish sample. Food Control 57:402–410. https://doi.org/10.1016/j.foodcont.2015.05.001
Jain U, Narang J, Rani K, Burna S, Chauhan N (2015) Synthesis of cadmium oxide and carbon nanotube based nanocomposites and their use as a sensing interface for xanthine detection. RSC Adv 5(38):29675–29683. https://doi.org/10.1039/C5RA00050E
Zhang L, Lei J, Zhang J, Ding L, Ju H (2012) Amperometric detection of hypoxanthine and xanthine by enzymatic amplification using a gold nanoparticles–carbon nanohorn hybrid as the carrier. Analyst 137(13):3126–3131. https://doi.org/10.1039/C2AN35284B
Devi R, Yadav S, Pundir CS (2012) Amperometric determination of xanthine in fish meat by zinc oxide nanoparticle/chitosan/multiwalled carbon nanotube/polyaniline composite film bound xanthine oxidase. Analyst 137(3):754–759. https://doi.org/10.1039/C1AN15838D
Sen S, Sarkar P (2015) A novel third-generation xanthine biosensor with enzyme modified glassy carbon electrode using electrodeposited MWCNT and nanogold polymer composite film. RSC Adv 5(116):95911–95925. https://doi.org/10.1039/C5RA18889J
Yazdanparast S, Benvidi A, Abbasi S, Rezaeinasab M (2019) Enzyme-based ultrasensitive electrochemical biosensor using poly(l-aspartic acid)/MWCNT bio-nanocomposite for xanthine detection: a meat freshness marker. Microchem J 149:104000. https://doi.org/10.1016/j.microc.2019.104000
Dervisevic M, Dervisevic E, Senel M, Cevik E, Abasiyanik FM (2017) Novel amperometric xanthine biosensors based on REGO-NP (Pt, Pd, and Au) bionanocomposite film. Food Anal Methods 10(5):1252–1263. https://doi.org/10.1007/s12161-016-0665-5
Narang J, Malhotra N, Singhal C, Pundir CS (2017) Evaluation of freshness of fishes using MWCNT/TiO2 Nanobiocomposites based biosensor. Food Anal Methods 10(2):522–528. https://doi.org/10.1007/s12161-016-0594-3
Anik U, Çubukçu M (2012) Application of bismuth(III)-entrapped XO biosensing system for xanthine determination in beverages. Food Anal Methods 5(4):716–722. https://doi.org/10.1007/s12161-011-9304-3
Zhang X, Dong J, Qian X, Zhao C (2015) One-pot synthesis of an RGO/ZnO nanocomposite on zinc foil and its excellent performance for the nonenzymatic sensing of xanthine. Sensors Actuators B Chem 221:528–536. https://doi.org/10.1016/j.snb.2015.06.039
Wang Z, Ma B, Shen C, Lai O-M, Tan C-P, Cheong L-Z (2019) Electrochemical biosensing of chilled seafood freshness by xanthine oxidase immobilized on copper-based metal–organic framework nanofiber film. Food Anal Methods. https://doi.org/10.1007/s12161-019-01513-8
Ghanbari K, Nejabati F (2019) Construction of novel nonenzymatic xanthine biosensor based on reduced graphene oxide/polypyrrole/CdO nanocomposite for fish meat freshness detection. J Food Meas Charact 13(2):1411–1422. https://doi.org/10.1007/s11694-019-00057-z
Saadaoui M, Sánchez A, Díez P, Raouafi N, Pingarrón JM, Villalonga R (2016) Amperometric xanthine biosensors using glassy carbon electrodes modified with electrografted porous silica nanomaterials loaded with xanthine oxidase. Microchim Acta 183(6):2023–2030. https://doi.org/10.1007/s00604-016-1840-5
Torres AC, Ghica ME, Brett CM (2013) Design of a new hypoxanthine biosensor: xanthine oxidase modified carbon film and multi-walled carbon nanotube/carbon film electrodes. Anal Bioanal Chem 405(11):3813–3822. https://doi.org/10.1007/s00216-012-6631-1
Pundir CS, Devi R (2014) Biosensing methods for xanthine determination: a review. Enzym Microb Technol 57:55–62. https://doi.org/10.1016/j.enzmictec.2013.12.006
Li Z, Wang L, Li Y, Feng Y, Feng W (2019) Carbon-based functional nanomaterials: preparation, properties and applications. Compos Sci Technol. https://doi.org/10.1016/j.compscitech.2019.04.028
Morin J-F (2014) From rods to sheets in a flash. Nat Chem 6:463. https://doi.org/10.1038/nchem.1962
Dervisevic M, Çevik E, Durmuş Z, Şenel M (2016) Electrochemical sensing platforms based on the different carbon derivative incorporated interface. Mater Sci Eng C 58:790–798. https://doi.org/10.1016/j.msec.2015.09.052
Baptista FR, Belhout SA, Giordani S, Quinn SJ (2015) Recent developments in carbon nanomaterial sensors. Chem Soc Rev 44(13):4433–4453. https://doi.org/10.1039/C4CS00379A
Cardenas-Benitez B, Djordjevic I, Hosseini S, Madou MJ, Martinez-Chapa SO (2018) Review—covalent functionalization of carbon nanomaterials for biosensor applications: An update. J Electrochem Soc 165(3):B103–B117. https://doi.org/10.1149/2.0381803jes
Basiuk EV, Basiuk VA (2015) Solvent-free functionalization of carbon nanomaterials. In: Basiuk VA, Basiuk EV (eds) Green processes for nanotechnology: from inorganic to bioinspired nanomaterials. Springer International Publishing, Cham, pp 163–205. https://doi.org/10.1007/978-3-319-15461-9_6
Zhu Y, Murali S, Cai W, Li X, Suk JW, Potts JR, Ruoff RS (2010) Graphene and graphene oxide: synthesis, properties, and applications. Adv Mater 22(35):3906–3924. https://doi.org/10.1002/adma.201001068
Das SK, Kc CB, Ohkubo K, Yamada Y, Fukuzumi S, D'Souza F (2013) Decorating single layer graphene oxide with electron donor and acceptor molecules for the study of photoinduced electron transfer. Chem Commun 49(20):2013–2015. https://doi.org/10.1039/C3CC38898K
Neklyudov VV, Khafizov NR, Sedov IA, Dimiev AM (2017) New insights into the solubility of graphene oxide in water and alcohols. Phys Chem Chem Phys 19(26):17000–17008. https://doi.org/10.1039/C7CP02303K
Kuila T, Bose S, Mishra AK, Khanra P, Kim NH, Lee JH (2012) Chemical functionalization of graphene and its applications. Prog Mater Sci 57(7):1061–1105. https://doi.org/10.1016/j.pmatsci.2012.03.002
Van Eekelen M (1936) On the amount of ascorbic acid in blood and urine. The daily human requirements for ascorbic acid. Biochem J 30(12):2291–2298. https://doi.org/10.1042/bj0302291
Janas D (2018) Towards monochiral carbon nanotubes: a review of progress in the sorting of single-walled carbon nanotubes. Mater Chem Front 2(1):36–63. https://doi.org/10.1039/C7QM00427C
Hodge SA, Bayazit MK, Coleman KS, Shaffer MSP (2012) Unweaving the rainbow: a review of the relationship between single-walled carbon nanotube molecular structures and their chemical reactivity. Chem Soc Rev 41(12):4409–4429. https://doi.org/10.1039/C2CS15334C
Tasis D, Tagmatarchis N, Bianco A, Prato M (2006) Chemistry of carbon nanotubes. Chem Rev 106(3):1105–1136. https://doi.org/10.1021/cr050569o
Zhou Y, Fang Y, Ramasamy RP (2019) Non-covalent functionalization of carbon nanotubes for electrochemical biosensor development. Sensors 19(2):392. https://doi.org/10.3390/s19020392
Dervisevic M, Dervisevic E, Şenel M (2018) Design of amperometric urea biosensor based on self-assembled monolayer of cystamine/PAMAM-grafted MWCNT/Urease. Sensors Actuators B Chem 254:93–101. https://doi.org/10.1016/j.snb.2017.06.161
Dervisevic E, Dervisevic M, Nyangwebah JN, Şenel M (2017) Development of novel amperometric urea biosensor based on Fc-PAMAM and MWCNT bio-nanocomposite film. Sensors Actuators B Chem 246:920–926. https://doi.org/10.1016/j.snb.2017.02.122
Arora B, Bhatia R, Attri P (2018) 28 - bionanocomposites: green materials for a sustainable future. In: Hussain CM, Mishra AK (eds) New Polymer Nanocomposites for Environmental Remediation. Elsevier, Amsterdam, pp 699–712. https://doi.org/10.1016/B978-0-12-811033-1.00027-5
Numata K, Kaplan DL (2011) 20 - biologically derived scaffolds. In: Farrar D (ed) Advanced wound repair therapies. Woodhead Publishing, Sawston-Cambridge, pp 524–551. https://doi.org/10.1533/9780857093301.4.524
Tiwari A, Tiwari A, Singh RP (2012) Bionanocomposite Matrices in Electrochemical Biosensors. In: Tiwari A, Ramalingam M, Kobayashi H, Turner APF (eds) Biomedical Materials and Diagnostic Devices. Scrivener Publishing, Beverly, pp 303–321 https://doi.org/10.1002/9781118523025.ch10
Siqueira G, Bras J, Dufresne A (2010) Cellulosic bionanocomposites: a review of preparation, properties and applications. Polymers 2(4):728–765
Azizi S, Ahmad MB, Hussein MZ, Ibrahim NA, Namvar F (2014) Preparation and properties of poly(vinyl alcohol)/chitosan blend bionanocomposites reinforced with cellulose nanocrystals/ZnO-ag multifunctional nanosized filler. Int J Nanomedicine 9:1909–1917. https://doi.org/10.2147/IJN.S60274
Sanaeifar N, Rabiee M, Abdolrahim M, Tahriri M, Vashaee D, Tayebi L (2017) A novel electrochemical biosensor based on Fe3O4 nanoparticles-polyvinyl alcohol composite for sensitive detection of glucose. Anal Biochem 519:19–26. https://doi.org/10.1016/j.ab.2016.12.006
Unal B, Yalcinkaya EE, Gumustas S, Sonmez B, Ozkan M, Balcan M, Demirkol DO, Timur S (2017) Polyglycolide–montmorillonite as a novel nanocomposite platform for biosensing applications. New J Chem 41(17):9371–9379. https://doi.org/10.1039/C7NJ01751K
Katz E, Willner I, Wang J (2004) Electroanalytical and bioelectroanalytical systems based on metal and semiconductor nanoparticles. Electroanalysis 16(1–2):19–44. https://doi.org/10.1002/elan.200302930
George JM, Antony A, Mathew B (2018) Metal oxide nanoparticles in electrochemical sensing and biosensing: a review. Microchim Acta 185(7):358. https://doi.org/10.1007/s00604-018-2894-3
Li Y, Tan B, Wu Y (2008) Mesoporous Co3O4 nanowire arrays for lithium ion batteries with high capacity and rate capability. Nano Lett 8(1):265–270. https://doi.org/10.1021/nl0725906
Kreno LE, Leong K, Farha OK, Allendorf M, Van Duyne RP, Hupp JT (2012) Metal–organic framework materials as chemical sensors. Chem Rev 112(2):1105–1125. https://doi.org/10.1021/cr200324t
Furukawa H, Cordova KE, O’Keeffe M, Yaghi OM (2013) The chemistry and applications of metal-organic frameworks. Science 341(6149):1230444. https://doi.org/10.1126/science.1230444
Xu Y, Li Q, Xue H, Pang H (2018) Metal-organic frameworks for direct electrochemical applications. Coord Chem Rev 376:292–318. https://doi.org/10.1016/j.ccr.2018.08.010
Fang X, Zong B, Mao S (2018) Metal–organic framework-based sensors for environmental contaminant sensing. Nano-Micro Lett 10(4):64. https://doi.org/10.1007/s40820-018-0218-0
Sadki S, Schottland P, Brodie N, Sabouraud G (2000) The mechanisms of pyrrole electropolymerization. Chem Soc Rev 29(5):283–293. https://doi.org/10.1039/A807124A
Teng Y, Liu F, Kan X (2017) Voltammetric dopamine sensor based on three-dimensional electrosynthesized molecularly imprinted polymers and polypyrrole nanowires. Microchim Acta 184(8):2515–2522. https://doi.org/10.1007/s00604-017-2243-y
Beluomini MA, da Silva JL, Stradiotto NR (2018) Amperometric determination of myo-inositol by using a glassy carbon electrode modified with molecularly imprinted polypyrrole, reduced graphene oxide and nickel nanoparticles. Microchim Acta 185(3):170. https://doi.org/10.1007/s00604-018-2710-0
Dervisevic M, Senel M, Sagir T, Isik S (2017) Highly sensitive detection of cancer cells with an electrochemical cytosensor based on boronic acid functional polythiophene. Biosens Bioelectron 90:6–12. https://doi.org/10.1016/j.bios.2016.10.100
Li Y, Yin S, Lu Y, Zhou H, Jiang H, Niu N, Huang H, Zhang L, Lo KK-W, Yu C (2017) Choline sensing based on in situ polymerization of aniline on the surface of upconverting nanoparticles. J Mater Chem B 5(38):7861–7865. https://doi.org/10.1039/C7TB01589E
Kozlovskaja S, Baltrūnas G, Malinauskas A (2009) Response of hydrogen peroxide, ascorbic acid, and paracetamol at a platinum electrode coated with microfilms of polyaniline. Microchim Acta 166(3):229–234. https://doi.org/10.1007/s00604-009-0185-8
Dervisevic M, Dervisevic E, Senel M, Cevik E, Yildiz HB, Camurlu P (2017) Construction of ferrocene modified conducting polymer based amperometric urea biosensor. Enzym Microb Technol 102:53–59. https://doi.org/10.1016/j.enzmictec.2017.04.002
Dervisevic M, Çevik E, Şenel M, Nergiz C, Abasiyanik MF (2016) Amperometric cholesterol biosensor based on reconstituted cholesterol oxidase on boronic acid functional conducting polymers. J Electroanal Chem 776:18–24. https://doi.org/10.1016/j.jelechem.2016.06.033
Greenlee L, Handler P (1964) Xanthine oxidase. VI. Influence of pH on substrate specificity. J Biol Chem 239:1090–1095
Krenitsky TA, Neil SM, Elion GB, Hitchings GH (1972) A comparison of the specificities of xanthine oxidase and aldehyde oxidase. Arch Biochem Biophys 150(2):585–599. https://doi.org/10.1016/0003-9861(72)90078-1
Shi W, Fan H, Ai S, Zhu L (2015) Pd nanoparticles supported on nitrogen, sulfur-doped three-dimensional hierarchical nanostructures as peroxidase-like catalysts for colorimetric detection of xanthine. RSC Adv 5(41):32183–32190. https://doi.org/10.1039/C5RA02312B
Qiao F, Wang J, Ai S, Li L (2015) As a new peroxidase mimetics: the synthesis of selenium doped graphitic carbon nitride nanosheets and applications on colorimetric detection of H2O2 and xanthine. Sensors Actuators B Chem 216:418–427. https://doi.org/10.1016/j.snb.2015.04.074
Li Z, Liu X, Liang X-H, Zhong J, Guo L, Fu F (2019) Colorimetric determination of xanthine in urine based on peroxidase-like activity of WO3 nanosheets. Talanta 204:278–284. https://doi.org/10.1016/j.talanta.2019.06.003
Li N, Than A, Wang X, Xu S, Sun L, Duan H, Xu C, Chen P (2016) Ultrasensitive profiling of metabolites using tyramine-functionalized graphene quantum dots. ACS Nano 10(3):3622–3629. https://doi.org/10.1021/acsnano.5b08103
Cui M, Zhou J, Zhao Y, Song Q (2017) Facile synthesis of iridium nanoparticles with superior peroxidase-like activity for colorimetric determination of H2O2 and xanthine. Sensors Actuators B Chem 243:203–210. https://doi.org/10.1016/j.snb.2016.11.145
Patil SB, Dheeman DS, Al-Rawhani MA, Velugotla S, Nagy B, Cheah BC, Grant JP, Accarino C, Barrett MP, Cumming DRS (2018) An integrated portable system for single chip simultaneous measurement of multiple disease associated metabolites. Biosens Bioelectron 122:88–94. https://doi.org/10.1016/j.bios.2018.09.013
Zhao Y, Liu H, Jiang Y, Song S, Zhao Y, Zhang C, Xin J, Yang B, Lin Q (2018) Detection of various biomarkers and enzymes via a nanocluster-based fluorescence turn-on sensing platform. Anal Chem 90(24):14578–14585. https://doi.org/10.1021/acs.analchem.8b04691
Ma Y, Cen Y, Sohail M, Xu G, Wei F, Shi M, Xu X, Song Y, Ma Y, Hu Q (2017) A ratiometric fluorescence universal platform based on N, Cu codoped carbon dots to detect metabolites participating in H2O2-generation reactions. ACS Appl Mater Interfaces 9(38):33011–33019. https://doi.org/10.1021/acsami.7b10548
Carrillo-Carrión C, Armenta S, Simonet BM, Valcárcel M, Lendl B (2011) Determination of pyrimidine and purine bases by reversed-phase capillary liquid chromatography with at-line surface-enhanced Raman spectroscopic detection employing a novel SERS substrate based on ZnS/CdSe silver–quantum dots. Anal Chem 83(24):9391–9398. https://doi.org/10.1021/ac201821q
Pu W, Zhao H, Wu L, Zhao X (2015) A colorimetric method for the determination of xanthine based on the aggregation of gold nanoparticles. Microchim Acta 182(1):395–400. https://doi.org/10.1007/s00604-014-1342-2
Yan Z, Niu Q, Mou M, Wu Y, Liu X, Liao S (2017) A novel colorimetric method based on copper nanoclusters with intrinsic peroxidase-like for detecting xanthine in serum samples. J Nanopart Res 19(7):235. https://doi.org/10.1007/s11051-017-3904-9
Salinas-Castillo A, Pastor I, Mallavia R, Mateo CR (2008) Immobilization of a trienzymatic system in a sol–gel matrix: a new fluorescent biosensor for xanthine. Biosens Bioelectron 24(4):1053–1056. https://doi.org/10.1016/j.bios.2008.07.052
Hu S, Yan J, Huang X, Guo L, Lin Z, Luo F, Qiu B, Wong K-Y, Chen G (2018) A sensing platform for hypoxanthine detection based on amino-functionalized metal organic framework nanosheet with peroxidase mimic and fluorescence properties. Sensors Actuators B Chem 267:312–319. https://doi.org/10.1016/j.snb.2018.04.055
Zhang Z, Kwok RTK, Yu Y, Tang BZ, Ng KM (2018) Aggregation-induced emission luminogen-based fluorescence detection of hypoxanthine: a probe for biomedical diagnosis of energy metabolism-related conditions. J Mater Chem B 6(28):4575–4578. https://doi.org/10.1039/C8TB00803E
Menon S, Girish Kumar K (2017) A fluorescent biosensor for the determination of xanthine in tea and coffee via enzymatically generated uric acid. LWT 86:8–13. https://doi.org/10.1016/j.lwt.2017.07.031
Chen Z, Lin Y, Ma X, Guo L, Qiu B, Chen G, Lin Z (2017) Multicolor biosensor for fish freshness assessment with the naked eye. Sensors Actuators B Chem 252:201–208. https://doi.org/10.1016/j.snb.2017.06.007
Cai S, Xiao W, Duan H, Liang X, Wang C, Yang R, Li Y (2018) Single-layer Rh nanosheets with ultrahigh peroxidase-like activity for colorimetric biosensing. Nano Res 11(12):6304–6315. https://doi.org/10.1007/s12274-018-2154-1
Xue G, Yu W, Yutong L, Qiang Z, Xiuying L, Yiwei T, Jianrong L (2019) Construction of a novel xanthine biosensor using zinc oxide (ZnO) and the biotemplate method for detection of fish freshness. Anal Methods 11(8):1021–1026. https://doi.org/10.1039/C8AY02554A
Kant R, Tabassum R, Gupta BD (2018) Xanthine oxidase functionalized Ta2O5 nanostructures as a novel scaffold for highly sensitive SPR based fiber optic xanthine sensor. Biosens Bioelectron 99:637–645. https://doi.org/10.1016/j.bios.2017.08.040
Ligler FS (2008) Fluorescence-based optical biosensors. In: Pavesi L, Fauchet PM (eds) Biophotonics. Springer Berlin Heidelberg, Berlin, Heidelberg, pp 199–215. https://doi.org/10.1007/978-3-540-76782-4_11
Jung HS, Verwilst P, Kim WY, Kim JS (2016) Fluorescent and colorimetric sensors for the detection of humidity or water content. Chem Soc Rev 45(5):1242–1256. https://doi.org/10.1039/C5CS00494B
Wegner KD, Hildebrandt N (2015) Quantum dots: bright and versatile in vitro and in vivo fluorescence imaging biosensors. Chem Soc Rev 44(14):4792–4834. https://doi.org/10.1039/C4CS00532E
Han M, Gao X, Su JZ, Nie S (2001) Quantum-dot-tagged microbeads for multiplexed optical coding of biomolecules. Nat Biotechnol 19(7):631–635. https://doi.org/10.1038/90228
Altintas Z, Davis F, Scheller FW (2018) Applications of quantum dots in biosensors and diagnostics. In: Altintas Z (ed) Biosensors and nanotechnology. Wiley, New York, pp 185–199. https://doi.org/10.1002/9781119065036.ch9
Sun H, Wu L, Wei W, Qu X (2013) Recent advances in graphene quantum dots for sensing. Mater Today 16(11):433–442. https://doi.org/10.1016/j.mattod.2013.10.020
Xu H, Li Q, Wang L, He Y, Shi J, Tang B, Fan C (2014) Nanoscale optical probes for cellular imaging. Chem Soc Rev 43(8):2650–2661. https://doi.org/10.1039/C3CS60309A
Li L, Wu G, Yang G, Peng J, Zhao J, Zhu J-J (2013) Focusing on luminescent graphene quantum dots: current status and future perspectives. Nanoscale 5(10):4015–4039. https://doi.org/10.1039/C3NR33849E
Sk MA, Ananthanarayanan A, Huang L, Lim KH, Chen P (2014) Revealing the tunable photoluminescence properties of graphene quantum dots. J Mater Chem C 2(34):6954–6960. https://doi.org/10.1039/C4TC01191K
Sun H, Zhao A, Gao N, Li K, Ren J, Qu X (2015) Deciphering a nanocarbon-based artificial peroxidase: chemical identification of the catalytically active and substrate-binding sites on graphene quantum dots. Angew Chem Int Ed 54(24):7176–7180. https://doi.org/10.1002/anie.201500626
Park KM, Shin YM, Joung YK, Shin H, Park KD (2010) In situ forming hydrogels based on tyramine conjugated 4-arm-PPO-PEO via enzymatic oxidative reaction. Biomacromolecules 11(3):706–712. https://doi.org/10.1021/bm9012875
Barbariga M, Curnis F, Andolfo A, Zanardi A, Lazzaro M, Conti A, Magnani G, Volonte MA, Ferrari L, Comi G, Corti A, Alessio M (2015) Ceruloplasmin functional changes in Parkinson's disease-cerebrospinal fluid. Mol Neurodegener 10:59. https://doi.org/10.1186/s13024-015-0055-2
Yuen JW, Benzie IF (2003) Hydrogen peroxide in urine as a potential biomarker of whole body oxidative stress. Free Radic Res 37(11):1209–1213
Forman HJ, Bernardo A, Davies KJA (2016) What is the concentration of hydrogen peroxide in blood and plasma? Arch Biochem Biophys 603:48–53. https://doi.org/10.1016/j.abb.2016.05.005
Xu X, Ray R, Gu Y, Ploehn HJ, Gearheart L, Raker K, Scrivens WA (2004) Electrophoretic analysis and purification of fluorescent single-walled carbon nanotube fragments. J Am Chem Soc 126(40):12736–12737. https://doi.org/10.1021/ja040082h
Jhonsi MA (2018) Carbon quantum dots for bioimaging. In: Ghamsari MS (ed) State of the Art in Nano-bioimaging. IntechOpen, London, pp 35–53 https://doi.org/10.5772/intechopen.72723
Harish Kumar K, Venkatesh N, Bhowmik H, Kuila A (2018) Metallic Nanoparticle: A Review. Biomed J Sci Technol Res 4(2):11. https://doi.org/10.26717/BJSTR.2018.04.001011
Chawla S (2016) Nanoparticles and fluorescence. In: Aliofkhazraei M (ed) Handbook of nanoparticles. Springer International Publishing, Cham, pp 961–983. https://doi.org/10.1007/978-3-319-15338-4_43
Chen P-C, Roy P, Chen L-Y, Ravindranath R, Chang H-T (2014) Gold and silver nanomaterial-based optical sensing systems. Part Part Syst Charact 31(9):917–942. https://doi.org/10.1002/ppsc.201400043
Ghosh SK, Pal T (2007) Interparticle coupling effect on the surface plasmon resonance of gold nanoparticles: from theory to applications. Chem Rev 107(11):4797–4862. https://doi.org/10.1021/cr0680282
Khlebtsov B, Tuchina E, Tuchin V, Khlebtsov N (2015) Multifunctional au nanoclusters for targeted bioimaging and enhanced photodynamic inactivation of Staphylococcus aureus. RSC Adv 5(76):61639–61649. https://doi.org/10.1039/C5RA11713E
Dou X, Yuan X, Yu Y, Luo Z, Yao Q, Leong DT, Xie J (2014) Lighting up thiolated Au@Ag nanoclusters via aggregation-induced emission. Nanoscale 6(1):157–161. https://doi.org/10.1039/C3NR04490D
Zhang P, Yang XX, Wang Y, Zhao NW, Xiong ZH, Huang CZ (2014) Rapid synthesis of highly luminescent and stable Au20 nanoclusters for active tumor-targeted imaging in vitro and in vivo. Nanoscale 6(4):2261–2269. https://doi.org/10.1039/C3NR05269A
Ruiyi L, Huiying W, Xiaoyan Z, Xiaoqing L, Xiulan S, Zaijun L (2016) d-Penicillamine and bovine serum albumin co-stabilized copper nanoclusters with remarkably enhanced fluorescence intensity and photostability for ultrasensitive detection of Ag+. New J Chem 40(1):732–739. https://doi.org/10.1039/C5NJ02615F
Ping J, Fan Z, Sindoro M, Ying Y, Zhang H (2017) Recent advances in sensing applications of two-dimensional transition metal dichalcogenide nanosheets and their composites. Adv Funct Mater 27(19):1605817. https://doi.org/10.1002/adfm.201605817
Choleva TG, Gatselou VA, Tsogas GZ, Giokas DL (2017) Intrinsic peroxidase-like activity of rhodium nanoparticles, and their application to the colorimetric determination of hydrogen peroxide and glucose. Microchim Acta 185(1):22. https://doi.org/10.1007/s00604-017-2582-8
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Dervisevic, M., Dervisevic, E. & Şenel, M. Recent progress in nanomaterial-based electrochemical and optical sensors for hypoxanthine and xanthine. A review. Microchim Acta 186, 749 (2019). https://doi.org/10.1007/s00604-019-3842-6
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DOI: https://doi.org/10.1007/s00604-019-3842-6