Skip to main content
Log in

Axonal polyglucosan body in the ventral posterolateral nucleus of the human thalamus in relation to ageing

  • Regular Papers
  • Published:
Acta Neuropathologica Aims and scope Submit manuscript

Summary

Axonal polyglucosan bodies in myelinated axons in the ventral posterolateral nucleus of the human thalamus (VPL) are described. These axonal inclusions were distributed exclusively in the dorsolateral part of the caudal VPL, and their arrangement may be associated with fibres originating from the gracile nucleus. They were not observed in patients under age of 50, and appeared to increase in number and size with advancing age. It is suggested that axonal polyglucosan bodies are an ageing phenomenon of the secondary sensory fibers.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Anzil AP, Herrlinger H, Blinzinger K, Kronski D (1974) Intraneuritic corpora amylacea. Virchows Arch [A] 364:297–301

    Google Scholar 

  • Boivie J (1978) Anatomical observations on the dorsal column nuclei, their thalamic projection and the cytoarchitecture of some somatosensory thalamic nuclei in the monkey. J Comp Neurol 178:17–48

    Google Scholar 

  • Brannon W, McCormick W, Lampert P (1967) Axonal dystrophy in the gracile nucleus of man. Acta Neuropathol (Berl) 9:1–6

    Google Scholar 

  • Defendini R, Markesber WR, Mastri AR, Duffy PE (1973) Hallervorden-Spatz disease and infantile neuroaxonal dystrophy. Ultrastructural observations, anatomical pathology and nosology. J Neurol Sci 20:7–23

    Google Scholar 

  • Fujisawa K (1967) An unique type of axonal alteration (so-called axonal dystrophy) as seen in Goll's nucleus of 277 cases of controls. A contribution to the pathology of aging process. Acta Neuropathol (Berl) 8:255–275

    Google Scholar 

  • Kalil K (1981) Projections of the cerebellar and dorsal column nuclei upon the thalamus of the rhesus monkey. J Comp Neurol 195:25–50

    Google Scholar 

  • Ramsey HJ (1965) Ultrastructure of corpora amylacea. J Neuropathol Exp Neurol 24:25–39

    Google Scholar 

  • Takahashi K, Agari M, Nakamura H (1975) Intra-axonal corpora amylacea in ventral and lateral horns of the spinal cord. Acta Neuropathol (Berl) 31:151–158

    Google Scholar 

  • Takahashi K, Iwata K, Nakamura H (1977) Intra-axonal corpora amylacea in the CNS. Acta Neuropathol (Berl) 37: 165–167

    Google Scholar 

  • Tracey DJ, Asanuma C, Jones EG, Porter R (1980) Thalamic relay to motor cortex: afferent pathways from brain stem, cerebellum, and spinal cord in monkeys. J Neurophysiol 44:532–553

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Mizutani, T., Satoh, J. & Morimatsu, Y. Axonal polyglucosan body in the ventral posterolateral nucleus of the human thalamus in relation to ageing. Acta Neuropathol 74, 9–12 (1987). https://doi.org/10.1007/BF00688332

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00688332

Key words

Navigation