Abstract
The most common benign mesenchymal tumor of the gynecologic tract is a leiomyoma, while the most frequent malignant mesenchymal neoplasms of this anatomic region in pediatric and adult patients are rhabdomyosarcoma and leiomyosarcoma, respectively. Because these entities are expertly covered elsewhere in this textbook, they are not discussed in this chapter. Instead, this section concentrates on the myriad of other less common mesenchymal processes that occasionally affect the female reproductive organs. We attempt to cover the better-documented and most relevant entities as comprehensively as space allows and include brief comments and/or references for rarer lesions. Supplemental data from the Tumor Registry of the former Armed Forces Institute of Pathology is included for selected topics. It is important to remember that some of the entities under discussion have only recently been recognized and remain works in progress. Readers are directed to standard soft tissue tumor texts for additional reading.
The views expressed in this chapter are those of the authors and do not necessarily reflect official policy or position of the Joint Pathology Center, the Department of the Army/Navy/Air Force, the Department of Defense, or any other department or agency within the US Government.
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References
Abbott JJ, Oliveira AM, Nascimento AG (2006) The prognostic significance of fibrosarcomatous transformation in dermatofibrosarcoma protuberans. Am J Surg Pathol 30:436–443
Abeler V, Nesland JM (1989) Alveolar soft-part sarcoma in the uterine cervix. Arch Pathol Lab Med 113:1179–1183
Afenyi-Annan A, Paulino AF (2001) Abnormal uterine bleeding. Arch Pathol Lab Med 125:1389–1390
Agaram NP, Sung YS, Zhang L et al (2015) Dichotomy of genetic abnormalities in PEComas with therapeutic implications. Am J Surg Pathol 39:813–825
Agarossi A, Vago L, Lazzarin A et al (1991) Vulvar Kaposi’s sarcoma. A case report. Ann Oncol 2:609–610
Ahern JK, Allen NH (1978) Cervical hemangioma: a case report and review of the literature. J Reprod Med 21:228–231
Alassiri AH, Ali RH, Shen Y et al (2016) ETV6-NTRK3 is expressed in a subset of ALK-negative inflammatory myofibroblastic tumors. Am J Surg Pathol 40:1051–1061
Albores-Saavedra J, Gilcrease M (1999) Glomus tumor of the uterine cervix. Int J Gynecol Pathol 18:69–72
Allen PW, Dymock RB, MacCormac LB (1988) Superficial angiomyxomas with and without epithelial components. Report of 30 tumors in 28 patients. Am J Surg Pathol 12:519–530
Altchek A, Deligdisch L, Norton K et al (2007) Prepubertal unilateral fibrous hyperplasia of the labium majus: report of eight cases and review of the literature. Obstet Gynecol 110:103–108
Althausen AM, Kowalski DP, Ludwig ME et al (2000) Granular cell tumors: a new clinically important histologic finding. Gynecol Oncol 77:310–313
Alvarez M, Cerezo L (1986) Ovarian cavernous hemangioma. Arch Pathol Lab Med 110:77–78
Alvarez-Canas MC, Mayorga M, Fernandez F et al (1996) Dermatofibrosarcoma protuberans of the vulva: clinico-pathological, immunohistochemical and flow cytometric study of a case. Acta Obstet Gynecol Scand 75:82–85
Ambani DS, White B, Kaplan AL et al (2006) A case of monophasic synovial sarcoma presenting as a vulvar mass. Gynecol Oncol 100:433–436
Aranda FI, Laforga JB (1998) Nodular fasciitis of the vulva. Report of a case with immunohistochemical study. Pathol Res Pract 194:805–807
Argani P, Ladanyi M (2003) Recent advances in pediatric renal neoplasia. Adv Anat Pathol 10:243–260
Argani P, Antonescu CR, Illei PB et al (2001) Primary renal neoplasms with the ASPL-TFE3 gene fusion of alveolar soft part sarcoma: a distinctive tumor entity previously included among renal cell carcinomas of children and adolescents. Am J Pathol 159:179–192
Argani P, Lal P, Hutchinson B et al (2003) Aberrant nuclear immunoreactivity for TFE3 in neoplasms with TFE3 gene fusions: a sensitive and specific immunohistochemical assay. Am J Surg Pathol 27:750–761
Argani P, Aulmann S, Illei PB et al (2010) A distinctive subset of PEComas harbors TFE3 gene fusions. Am J Surg Pathol 34:1395–1406
Argenta PA, Thomas S, Chura JC (2007) “Proximal-type” epithelioid sarcoma vs. malignant rhabdoid tumor of the vulva: a case report, review of the literature, and an argument for consolidation. Gynecol Oncol 107:130–135
Audouin AF, Lopes P, Lenne Y (1988) Sarcoma de Kaposi du col utérin associé á un condylome atypique chez une femme transplantée cardiaque (lors du post-partum). Arch Anat Cytol Path 36:226–228
Autio-Harmainen H, Apaja-Sarkkinen M, Martikainen J et al (1986) Production of basement membrane laminin and type IV collagen by tumors of striated muscle: an immunohistochemical study of rhabdomyosarcomas of different histologic types and a benign vaginal rhabdomyoma. Hum Pathol 17:1218–1224
Aynardi JT, Kim SH, Barroeta JE (2016) Epithelioid glomus tumor of the uterine cervix: a case report and review. Int J Gynecol Pathol 35:275–278
Azuno Y, Yaga K, Suehiro Y et al (2003) Inflammatory myoblastic tumor of the uterus and interleukin-6. Am J Obstet Gynecol 189:890–891
Bancalari E, de Álava E, Tardío JC (2012) Primary vaginal Ewing sarcoma: case report and review of the literature. Int J Surg Pathol 20:305–310
Banet N, Ning Y, Montgomery EA (2015) Inflammatory myofibroblastic tumor of the placenta: a report of a novel lesion in 2 patients. Int J Gynecol Pathol 34:419–423
Bennett JA, Sanada S, Selig MK et al (2015) Giant cell tumor of the uterus: a report of 3 cases with a spectrum of morphologic features. Int J Gynecol Pathol 34:340–350
Bennett JA, Nardi V, Rouzbahman M et al (2017) Inflammatory myofibroblastic tumor of the uterus: a clinicopathological, immunohistochemical, and molecular analysis of 13 cases highlighting their broad morphologic spectrum. Mod Pathol 30:1489–1503
Bennett JA, Braga AC, Pinto A et al (2018) Uterine PEComas: A morphologic, immunohistochemical, and molecular analysis of 32 tumors. Am J Surg Pathol 42:1370–1383
Bergh P, Meis-Kindblom JM, Gherlinzoni F et al (1999) Synovial sarcoma: identification of low and high risk groups. Cancer 85:2596–2607
Bhandari RN, Dragun AE, Aguero EG et al (2006) External beam radiotherapy for perirectal angiomyxoma results in a dramatic clinical response and allows a patient to avoid abdominoperineal resection. Am J Clin Oncol 29:318–319
Bhargava R, Shia J, Hummer AJ et al (2005) Distinction of endometrial stromal sarcomas from “hemangiopericytomatous” tumors using a panel of immunohistochemical stains. Mod Pathol 18:40–47
Bhattacharya B, Dilworth HP, Iacobuzio-Donahue C et al (2005) Nuclear beta-catenin expression distinguishes deep fibromatosis from other benign and malignant fibroblastic and myofibroblastic lesions. Am J Surg Pathol 29:653–659
Biedrzycki OJ, Singh N, Habeeb H et al (2007a) Solitary fibrous tumor of the female genital tract a case report and review of the literature. Int J Gynecol Pathol 26:259–264
Biedrzycki OJ, Singh N, Faruqi A (2007b) Nodular fasciitis of the vulva with an unusually long clinical history; the importance of making this unexpected diagnosis in such an unusual site. Histopathology 51:547–550
Bigby SM, Symmans PJ, Miller MV et al (2011) Aggressive angiomyxoma [corrected] of the female genital tract and pelvis – clinicopathologic features with immunohistochemical analysis. Int J Gynecol Pathol 30:505–513
Billings SD, Folpe AL, Weiss SW (2003) Epithelioid sarcoma-like hemangioendothelioma. Am J Surg Pathol 27:48–57
Billings SD, Giblen G, Fanburg-Smith JC (2005) Superficial low-grade fibromyxoid sarcoma (Evans tumor): a clinicopathologic analysis of 19 cases with a unique observation in the pediatric population. Am J Surg Pathol 29:204–210
Blandamura S, Cruz J, Faure Vergara L et al (2003) Aggressive angiomyxoma: a second case of metastasis with patient’s death. Hum Pathol 34:1072–1074
Blickstein I, Lurie S (1990) The gynaecological problems of neurofibromatosis. Aust N Z Obstet Gynaecol 30:380–382
Bock JE, Andreasson B, Thorn A et al (1985) Dermatofibrosarcoma protuberans of the vulva. Gynecol Oncol 20:129–135
Boikos SA, Stratakis CA (2006) Carney complex: pathology and molecular genetics. Neuroendocrinology 83:189–199
Boldorini R, Riboni F, Cristina S et al (2010) Primary vulvar Ewing’s sarcoma/primitive neuroectodermal tumor in a post-menopausal woman: a case report. Pathol Res Pract 15:476–479
Bonetti F, Martignoni G, Colato C et al (2001) Abdominopelvic sarcoma of perivascular epithelioid cells. Report of four cases in young women, one with tuberous sclerosis. Mod Pathol 14:563–568
Bos GD, Pritchard DJ, Reiman HM et al (1988) Epithelioid sarcoma. An analysis of fifty-one cases. J Bone Joint Surg Am 70:862–870
Brandfass RT, Everts-Suarez EA (1955) Lipomatous tumors of the uterus: a review of the world’s literature with report of a case of true lipoma. Am J Obstet Gynecol 70:359–367
Brasfield RD, Das Gupta TK (1972) Von Recklinghausen’s disease: a clinicopathological study. Ann Surg 175:86–104
Bridge JA, Kanamori M, Ma Z et al (2001) Fusion of the ALK gene to clathrin heavy chain gene, CLTC, in inflammatory myofibroblastic tumor. Am J Pathol 159:411–415
Brooks JJ, LiVolsi VA (1987) Liposarcoma presenting on the vulva. Am J Obstet Gynecol 156:73–75
Burch DJ, Hitchcock A, Masson GM (1994) Alveolar soft part sarcoma of the uterus: case report and review of the literature. Gynecol Oncol 54:91–94
Busby JG (1952) Neurofibromatosis of the cervix. Am J Obstet Gynecol 63:674–675
Calonje E, Fletcher CD (1996) Myoid differentiation in dermatofibrosarcoma protuberans and its fibrosarcomatous variant: clinicopathologic analysis of 5 cases. J Cutan Pathol 23:30–36
Calonje E, Guerin D, McCormick D et al (1999) Superficial angiomyxoma: clinicopathologic analysis of a series of distinctive but poorly recognized cutaneous tumors with tendency for recurrence. Am J Surg Pathol 23:910–917
Cambruzzi E, Pegas KL, Milani DM et al (2010) Angiosarcoma arising in an ovarian fibroma: a case report. Pathol Res Int 2010:842592
Cao D, Srodon M, Montgomery EA et al (2005) Lipomatous variant of angiomyofibroblastoma: report of two cases and review of the literature. Int J Gynecol Pathol 24:196–200
Carinelli SG, Giudici MN, Brioschi D et al (1990) Alveolar soft part sarcoma of the vagina. Tumori 76:77–80
Carlson JW, Fletcher CD (2007) Immunohistochemistry for beta-catenin in the differential diagnosis of spindle cell lesions: analysis of a series and review of the literature. Histopathology 51:509–514
Carney JA, Headington JT, Su WP (1986) Cutaneous myxomas. A major component of the complex of myxomas, spotty pigmentation, and endocrine overactivity. Arch Dermatol 122:790–798
Carter JM, Weiss SW, Linos K et al (2014) Superficial CD34-positive fibroblastic tumor: report of 18 cases of a distinctive low-grade mesenchymal neoplasm of intermediate (borderline) malignancy. Mod Pathol 27:294–302
Cenacchi G, Pasquinelli G, Montanaro L et al (1998) Primary endocervical extraosseous Ewing’s sarcoma/PNET. Int J Gynecol Pathol 17:83–88
Cerri A, Gianni C, Corbellino M et al (1998) Lymphangiosarcoma of the pubic region: a rare complication arising in congenital non-hereditary lymphedema. Eur J Dermatol 8:511–514
Cetiner H, Kir G, Gelmann EP et al (2009) Primary vulvar Ewing sarcoma/primitive peripheral neuroectodermal tumor: a report of 2 cases and review of the literature. Int J Gynecol Cancer 19:1131–1136
Chamberlain BK, McClain CM, Gonzalez RS et al (2014) Alveolar soft part sarcoma and granular cell tumor: an immunohistochemical comparison study. Hum Pathol 45:1039–1044
Chan WW, SenGupta SK (1991) Postirradiation angiosarcoma of the vaginal vault. Arch Pathol Lab Med 115:527–528
Chan IM, Hon E, Ngai SW et al (2000) Aggressive angiomyxoma in females: is radical resection the only option? Acta Obstet Gynecol Scand 79:216–220
Chapman GW, Benda J, Williams T (1984) Alveolar soft-part sarcoma of the vagina. Gynecol Oncol 18:125–129
Char G, Hanchard B, Manjoo RB (1982) Neurofibromatosis of the cervix uteri. West Indian Med J 31:90–92
Chase DR, Enzinger FM (1985) Epithelioid sarcoma. Diagnosis, prognostic indicators, and treatment. Am J Surg Pathol 9:241–263
Cheah AL, Billings SD, Goldblum JR et al (2014) STAT6 rabbit monoclonal antibody is a robust diagnostic tool for the distinction of solitary fibrous tumour from its mimics. Pathology 46:389–395
Chen E, Fletcher CD (2010) Cellular angiofibroma with atypia or sarcomatous transformation: clinicopathologic analysis of 13 cases. Am J Surg Pathol 34:707–714
Chen G, Folpe AL, Colby TV et al (2011) Angiomatoid fibrous histiocytoma: unusual sites and unusual morphology. Mod Pathol 24:1560–1570
Chen BJ, Marino-Enriquez A, Fletcher CD et al (2012) Loss of retinoblastoma protein expression in spindle cell/pleomorphic lipomas and genetically related tumors: an immunohistochemical study with diagnostic implications. Am J Surg Pathol 36:1119–1128
Cheng L, Scheithauer BW, Leibovich BC (1999) Neurofibroma of the urinary bladder. Cancer 86:505–513
Chestnut DH, Szpak CA, Fortier KJ et al (1988) Uterine hemangioma associated with infertility. South Med J 81:926–928
Chiang S, Snuderl M, Kojiro-Sanada S et al (2017) Primitive neuroectodermal tumors of the female genital tract: A morphologic, immunohistochemical, and molecular study of 19 cases. Am J Surg Pathol 41:761–772
Chien AJ, Freeby JA, Win TT et al (1998) Aggressive angiomyxoma of the female pelvis: sonographic, CT, and MR findings. AJR Am J Roentgenol 171:530–531
Chiodi NE, Siegel IA, Guerin PF et al (1957) Granular-cell myoblastoma of the vulva and lower respiratory tract: report of a case. Obstet Gynecol 9:472–480
Chmielecki J, Crago AM, Rosenberg M et al (2013) Whole-exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors. Nat Genet 45:131–132
Chu PW, Liu JY, Peng YJ et al (2006) Solitary fibrous tumor of the uterus. Taiwan J Obstet Gynecol 45:350–352
Chuang WY, Yeh CJ, Jung SM et al (2007) Plexiform schwannoma of the clitoris. APMIS 115:889–890
Chugh R, Wathen JK, Patel SR et al (2010) Efficacy of imatinib in aggressive fibromatosis: results of a phase II multicenter Sarcoma Alliance for Research through Collaboration (SARC) trial. Clin Cancer Res 16:4884–4891
Clement PB (1978) Chondrosarcoma of the uterus: report of a case and review of the literature. Hum Pathol 9:726–732
Clement PB (1988) Postoperative spindle-cell nodule of the endometrium. Arch Pathol Lab Med 112:566–568
Cohen PR, Yaw JR, Tovell HM (1989) Angiokeratoma of the vulva: diagnosis and review of the literature. Obstet Gynecol Surv 44:339–346
Colgan TJ, Dardick I, O’Connell G (1991) Paraganglioma of the vulva. Int J Gynecol Pathol 10:203–208
Comstock CH, Monticello ML, Johnson TW et al (2005) Cavernous hemangioma: diffuse enlarged venous spaces within the myometrium in pregnancy. Obstet Gynecol 106:1212–1214
Conlon N, Soslow RA, Murali R (2015) Perivascular epithelioid tumours (PEComas) of the gynaecological tract. J Clin Pathol 68:418–426
Contreras AL, Malpica A (2009) Angiosarcoma arising in mature cystic teratoma of the ovary: a case report and review of the literature. Int J Gynecol Pathol 28:453–457
Cook CL, Sanfilippo JS, Verdi GD et al (1989) Capillary hemangioma of the vagina and urethra in a child: response to short-term steroid therapy. Obstet Gynecol 73:883–885
Cormio G, Cormio L, Marzullo A et al (1997) Fibromatosis of the female pelvis. Ann Chir Gynaecol 86:84–86
Cunningham MJ, Brooks JS, Noumoff JS (1994) Treatment of primary ovarian angiosarcoma with ifosfamide and doxorubicin. Gynecol Oncol 53:265–268
Curry JL, Olejnik JL, Wojcik EM (2001) Cellular angiofibroma of the vulva with DNA ploidy analysis. Int J Gynecol Pathol 20:200–203
Czuczwar P, Stepniak A, Szkodziak P et al (2016) Unusual location of a plexiform neurofibroma in the fallopian tube: a case report. J Obstet Gynaecol Res 42:1618–1622
D’Antonio A, Caleo A, Boscaino A et al (2010) Vulvar lymphoedematous pseudotumours mistaken for aggressive angiomyxoma: report of two cases. Gynecol Obstet Investig 69:212–216
Dane B, Dane C, Basaran S et al (2010) Vaginal schwannoma in a case with uterine myoma. Ann Diagn Pathol 14:137–139
Davani M, Chablani VN, Saba PR (1998) Aggressive angiomyxoma of pelvic soft tissues: MR imaging appearance. AJR Am J Roentgenol 170:1113–1114
Davis GD, Patton WS (1983) Capillary hemangioma of the cervix and vagina: management with carbon dioxide laser. Obstet Gynecol 62:95S–96S
Davos I, Abell MR (1976) Sarcomas of the vagina. Obstet Gynecol 47:342–350
Dawood MY, Teoh ES, Ratnam SS (1972) Ruptured haemangioma of a gravid uterus. J Obstet Gynaecol Br Commonw 79:474–475
Daya D, Lukka H, Clement PB (1992) Primitive neuroectodermal tumors of the uterus: a report of four cases. Hum Pathol 23:1120–1129
De Young B, Bitterman P, Lack EE (1992) Primary osteosarcoma of the uterus: report of a case with immunohistochemical study. Mod Pathol 5:212–215
Demicco EG, Wagner MJ, Maki RG et al (2017) Risk assessment in solitary fibrous tumors: validation and refinement of a risk stratification model. Mod Pathol 30:1433–1442
den Bakker MA, Ansink AC, Ewing-Graham PC (2006) “Cutaneous-type” angiosarcoma arising in a mature cystic teratoma of the ovary. J Clin Pathol 59:658–660
Devaney K, Tavassoli FA (1991) Immunohistochemistry as a diagnostic aid in the interpretation of unusual mesenchymal tumors of the uterus. Mod Pathol 4:225–231
Dharkar DD, Kraft JR, Gangadharam D (1981) Uterine lipomas. Arch Pathol Lab Med 105:43–45
Di Sant’Agnese PA, Knowles DM 2nd (1980) Extracardiac rhabdomyoma: a clinicopathologic study and review of the literature. Cancer 46:780–789
Dickson MA, Schwartz GK, Antonescu CR et al (2013) Extrarenal perivascular epithelioid cell tumors (PEComas) respond to mTOR inhibition: clinical and molecular correlates. Int J Cancer 132:1711–1717
Doyle LA, Vivero M, Fletcher CD et al (2014) Nuclear expression of STAT6 distinguishes solitary fibrous tumor from histologic mimics. Mod Pathol 27:390–395
Drachenberg CB, Faust FJ, Borkowski A et al (1994) Epithelioid angiosarcoma of the uterus arising in a leiomyoma with associated ovarian and tubal angiomatosis. Am J Clin Pathol 102:388–389
Dreux N, Marty M, Chibon F et al (2010) Value and limitation of immunohistochemical expression of HMGA2 in mesenchymal tumors: about a series of 1052 cases. Mod Pathol 23:1657–1666
DuBay D, Cimmino V, Lowe L et al (2004) Low recurrence rate after surgery for dermatofibrosarcoma protuberans: a multidisciplinary approach from a single institution. Cancer 100:1008–1016
Ducatman BS, Scheithauer BW, Piepgras DG et al (1986) Malignant peripheral nerve sheath tumors: a clinicopathologic study of 120 cases. Cancer 57:2006–2021
Dundr P, Němejcová K, Laco J et al (2017) Anastomosing hemangioma of the ovary: a clinicopathologic study of six cases with stromal luteinization. Pathol Oncol Res 23:717–722
Duran B, Guvenal T, Yildiz E et al (2004) An unusual cause of adnexal mass: fallopian tube schwannoma. Gynecol Oncol 92:343–346
Eastley N, McCulloch T, Esler C et al (2016) Extra-abdominal desmoid fibromatosis: a review of management, current guidance and unanswered questions. Eur J Surg Oncol 42:1071–1083
Edelweiss M, Malpica A (2010) Dermatofibrosarcoma protuberans of the vulva: a clinicopathologic and immunohistochemical study of 13 cases. Am J Surg Pathol 34:393–400
Ellison DW, MacKenzie IZ, McGee JO (1992) Cellular schwannoma of the vagina. Gynecol Oncol 46:119–121
Emoto M, Tamura R, Izumi H et al (1997) Sonodynamic changes after transcatheter arterial embolization in a vaginal hemangioma: case report. Ultrasound Obstet Gynecol 10:66–67
Enzinger FM (1970) Epithelioid sarcoma. A sarcoma simulating a granuloma or a carcinoma. Cancer 26:1029–1041
Enzinger FM, Smith BH (1976) Hemangiopericytoma. An analysis of 106 cases. Hum Pathol 7:61–82
Erickson-Johnson RM, Chou MM, Evers BR et al (2011) Nodular fasciitis: a novel model of transient neoplasia induced by MYH9-USP6 gene fusion. Lab Investig 91:1427–1433
Espat NJ, Lewis JJ, Leung D et al (2002) Conventional hemangiopericytoma: modern analysis of outcome. Cancer 95:1746–1751
Euscher ED, Deavers MT, Lopez-Terrada D et al (2008) Uterine tumors with neuroectodermal differentiation: a series of 17 cases and review of the literature. Am J Surg Pathol 32:219–228
Fadare O (2006) Uncommon sarcomas of the uterine cervix: a review of selected entities. Diagn Pathol 1:30
Fadare O (2008a) Perivascular epithelioid cell tumor (PEComa) of the uterus: an outcome-based clinicopathologic analysis of 41 reported cases. Adv Anat Pathol 15:63–75
Fadare O (2008b) Uterine PEComa: appraisal of a controversial and increasingly reported mesenchymal neoplasm. Int Semin Surg Oncol 5:7
Fadare O, Parkash V, Yilmaz Y et al (2004) Perivascular epithelioid cell tumor (PEComa) of the uterine cervix associated with intraabdominal “PEComatosis”: a clinicopathologic study with comparative genomic hybridization analysis. World J Surg Oncol 2:35
Fadare O, Bossuyt V, Martel M et al (2006a) Primary osteosarcoma of the ovary: a case report and literature review. Int J Gynecol Pathol 26:21–25
Fadare O, Ghofrani M, Stamatakos MD et al (2006b) Mesenchymal lesions of the uterine cervix. Pathol Case Rev 11:140–152
Fadare O, Bonvicino A, Martel M et al (2010) Pleomorphic rhabdomyosarcoma of the uterine corpus: a clinicopathologic study of 4 cases and a review of the literature. Int J Gynecol Pathol 29:122–134
Fanburg-Smith JC, Meis-Kindblom JM, Fante R et al (1998) Malignant granular cell tumor of soft tissue: diagnostic criteria and clinicopathologic correlation. Am J Surg Pathol 22:779–794
Ferguson SE, Gerald W, Barakat RR et al (2007) Clinicopathologic features of rhabdomyosarcoma of gynecologic origin in adults. Am J Surg Pathol 31:382–389
Fernández-Aguilar S, Fayt I, Noel JC (2004) Spindle cell vulvar hemangiomatosis associated with enchondromatosis: a rare variant of Maffucci’s syndrome. Int J Gynecol Pathol 23:68–70
Fetsch JF, Laskin WB, Lefkowitz M et al (1996) Aggressive angiomyxoma: a clinicopathologic study of 29 female patients. Cancer 78:79–90
Fetsch JF, Laskin WB, Tavassoli FA (1997) Superficial angiomyxoma (cutaneous myxoma): a clinicopathologic study of 17 cases arising in the genital region. Int J Gynecol Pathol 16:325–334
Fine BA, Munoz AK, Litz CE et al (2001) Primary medical management of recurrent aggressive angiomyxoma with a gonadotrophin-releasing hormone agonist. Gynecol Oncol 81:120–122
Fingerland A (1938) Ganglioneuroma of the cervix uteri. J Pathol Bacteriol 47:631–634
Fischer G, Odunsi K, Lele S et al (2006) Ovarian primary primitive neuroectodermal tumor coexisting with endometrioid adenocarcinoma: a case report. Int J Gynecol Pathol 25:151–154
Fisher C (2004) Myofibroblastic malignancies. Adv Anat Pathol 11:190–201
Fisher C (2006) Epithelioid sarcoma of Enzinger. Adv Anat Pathol 13:114–121
Fisher C, Folpe AL, Hashimoto H et al (2004) Intra-abdominal synovial sarcoma: a clinicopathological study. Histopathology 45:245–253
Fishman A, Girtanner RE, Kaplan AL (1996) Aggressive fibromatosis of the female pelvis. A case report and review of the literature. Eur J Gynaecol Oncol 17:208–211
Fletcher CD, Tsang WY, Fisher C et al (1992) Angiomyofibroblastoma of the vulva. A benign neoplasm distinct from aggressive angiomyxoma. Am J Surg Pathol 16:373–382
Flint A, Gikas PW, Roberts JA (1985) Alveolar soft part sarcoma of the uterine cervix. Gynecol Oncol 22:263–267
Flucke U, van Krieken JH, Mentzel T (2011) Cellular angiofibroma: analysis of 25 cases emphasizing its relationship to spindle cell lipoma and mammary-type myofibroblastoma. Mod Pathol 24:82–89
Folpe AL, Mentzel T, Lehr HA et al (2005) Perivascular epithelioid cell neoplasms of soft tissue and gynecologic origin: a clinicopathologic study of 26 cases and review of the literature. Am J Surg Pathol 29:1558–1575
Folpe AL, Schoolmeester JK, McCluggage WG et al (2015) SMARCB1-deficient vulvar neoplasms: a clinicopathologic, immunohistochemical, and molecular genetic study of 14 cases. Am J Surg Pathol 39:836–849
Fong YE, López-Terrada D, Zhai QJ (2008) Primary Ewing sarcoma/peripheral primitive neuroectodermal tumor of the vulva. Hum Pathol 39:1535–1539
Foschini MP, Eusebi V, Tison V (1989) Alveolar soft part sarcoma of the cervix uteri. A case report. Pathol Res Pract 184:354–358
Fuehrer NE, Keeney GL, Ketterling RP et al (2012) ALK-1 protein expression and ALK gene rearrangements aid in the diagnosis of inflammatory myofibroblastic tumors of the female genital tract. Arch Pathol Lab Med 136:623–626
Fukunaga M (2000) Atypical solitary fibrous tumor of the vulva. Int J Gynecol Pathol 19:164–168
Fukunaga M, Nomura K, Matsumoto K et al (1997) Vulval angiomyofibroblastoma. Clinicopathologic analysis of six cases. Am J Clin Pathol 107:45–51
Gal R, Dekel A, Ben-David M et al (1988) Granular cell myoblastoma of the cervix. Case report. Br J Obstet Gyneacol 95:720–722
Ganesan R, McCluggage WG, Hirschowitz L et al (2005) Superficial myofibroblastoma of the lower female genital tract: report of a series including tumours with a vulvar location. Histopathology 46:137–143
Gantchev S (1997) Vascular abnormalities of the uterus, concerning a case of diffuse cavernous angiomatosis of the uterus. Gen Diagn Pathol 143:71–74
Gehrig PA, Fowler WC Jr, Lininger RA (2000) Ovarian capillary hemangioma presenting as an adnexal mass with massive ascites and elevated CA-125. Gynecol Oncol 76:130–132
Gengler C, Guillou L (2006) Solitary fibrous tumour and haemangiopericytoma: evolution of a concept. Histopathology 48:63–74
Gersell DJ, Fulling KH (1989) Localized neurofibromatosis of the female genitourinary tract. Am J Surg Pathol 13:873–878
Ghorbani RP, Malpica A, Ayala AG (1999) Dermatofibrosarcoma protuberans of the vulva: clinicopathologic and immunohistochemical analysis of four cases, one with fibrosarcomatous change, and review of the literature. Int J Gynecol Pathol 18:366–373
Gifford RR, Birch HW (1973) Granular cell myoblastoma of multicentric origin involving the vulva: a case report. Am J Obstet Gynecol 117:184–187
Gilks CB, Taylor GP, Clement PB (1987) Inflammatory pseudotumor of the uterus. Int J Gynecol Pathol 6:275–286
Giordano G, D’Adda T, Varotti E et al (2016) Primary alveolar soft part sarcoma of uterine corpus: a case report with immunohistochemical, ultrastructural study and review of literature. World J Surg Oncol 14:24
Gloster HM Jr, Harris KR, Roenigk RK (1996) A comparison between Mohs micrographic surgery and wide surgical excision for the treatment of dermatofibrosarcoma protuberans. J Am Acad Dermatol 35:82–87
Goette DK, Detlefs RL (1985) Postirradiation angiosarcoma. J Am Acad Dermatol 12:922–926
Gökden N, Dehner LP, Zhu X et al (2003) Dermatofibrosarcoma protuberans of the vulva and groin: detection of COL1A1-PDGFB fusion transcripts by RT-PCR. J Cutan Pathol 30:190–195
Gold BM (1972) Neurofibromatosis of the bladder and vagina. Am J Obstet Gynecol 113:1055–1056
Gold JH, Bossen EH (1976) Benign vaginal rhabdomyoma: a light and electron microscopic study. Cancer 37:2283–2294
Gold JS, Antonescu CR, Hajdu C et al (2002) Clinicopathologic correlates of solitary fibrous tumors. Cancer 94:1057–1068
Goldberg JM, Gavcovich T, Saigal G et al (2014) Extended progression-free survival in two patients with alveolar soft part sarcoma exposed to tivantinib. J Clin Oncol 32:e114–e116
Gordon MD, Weilert M, Ireland K (1996) Plexiform neurofibromatosis involving the uterine cervix, endometrium, myometrium, and ovary. Obstet Gynecol 88:699–701
Granter SR, Nucci MR, Fletcher CD (1997) Aggressive angiomyxoma: reappraisal of its relationship to angiomyofibroblastoma in a series of 16 cases. Histopathology 30:3–10
Gray GF Jr, Glick AD, Kurtin PJ et al (1986) Alveolar soft part sarcoma of the uterus. Hum Pathol 17:297–300
Griffin CA, Hawkins AL, Dvorak C et al (1999) Recurrent involvement of 2p23 in inflammatory myofibroblastic tumors. Cancer Res 59:2776–2780
Gücer F, Özyilmaz F, Balkanli-Kaplan P et al (2004) Ovarian hemangioma presenting with hyperandrogenism and endometrial cancer: a case report. Gynecol Oncol 94:821–824
Guillou L, Lamoureux E, Masse S et al (1991) Alveolar soft-part sarcoma of the uterine corpus: histological, immunocytochemical, and ultrastructural study of a case. Vircows Archiv A Pathol Anat 418:467–471
Guillou L, Wadden C, Coindre JM et al (1997) “Proximal-type” epithelioid sarcoma, a distinctive aggressive neoplasm showing rhabdoid features. Clinicopathologic, immunohistochemical, and ultrastructural study of a series. Am J Surg Pathol 21:130–146
Guillou L, Gebhard S, Coindre JM (2000) Orbital and extraorbital giant cell angiofibroma: a giant cell-rich variant of solitary fibrous tumor? Clinicopathologic and immunohistochemical analysis of a series in favor of a unifying concept. Am J Surg Pathol 24:971–979
Guillou L, Benhattar J, Bonichon F et al (2004) Histologic grade, but not SYT-SSX fusion type, is an important prognostic factor in patients with synovial sarcoma: a multicenter, retrospective analysis. J Clin Oncol 22:4040–4050
Guirguis A, Kanbour-Shakir A, Kelley J (2007) Epithelioid angiosarcoma of the mons after chemoradiation for vulvar cancer. Int J Gynecol Pathol 26:265–268
Gupta R, Singh S, Nigam S et al (2006) Benign vascular tumors of the female genital tract. Int J Gynecol Cancer 16:1195–1200
Gusdon JP (1965) Hemangioma of the cervix: four new cases and a review. Am J Obstet Gynecol 91:204–209
Gutmann DH, Aylsworth A, Carey JC et al (1997) The diagnostic evaluation and multidisciplinary management of neurofibromatosis 1 and neurofibromatosis 2. JAMA 278:51–57
Gwavava NJ, Traub AI (1980) A neurilemmoma of the cervix. Br J Obstet Gynaecol 87:444–446
Haimes JD, Stewart CJR, Kudlow BA et al (2017) Uterine inflammatory myofibroblastic tumors frequently harbor ALK fusions with IGFBP5 and THBS1. Am J Surg Pathol 41:773–780
Halling AC, Wollan PC, Pritchard DJ et al (1996) Epithelioid sarcoma: a clinicopathologic review of 55 cases. Mayo Clin Proc 71:636–642
Hanafy A, Lee RM, Peterson CM (1997) Schwannoma presenting as a Bartholin’s gland abscess. Aust N Z J Obstet Gynaecol 37:483–484
Haraoka M, Naito S, Kumazawa J (1988) Clitoral involvement by neurofibromatosis: a case report and review of the literature. J Urol 139:95–96
Hardisson D, Simón RS, Burgos E (2001) Primary osteosarcoma of the uterine corpus: report of a case with immunohistochemical and ultrastructural study. Gynecol Oncol 82:181–186
Hasagawa T, Matsuno Y, Shimoda T et al (1999) Extrathoracic solitary fibrous tumors: their histological variability and potentially aggressive behavior. Hum Pathol 30:1464–1473
Hasegawa T, Matsuno Y, Shimoda T et al (2001) Proximal-type epithelioid sarcoma: a clinicopathologic study of 20 cases. Mod Pathol 14:655–663
Hassan A, Bennet A, Bhalla S et al (2003) Paraganglioma of the vagina: report of a case, including immunohistochemical and ultrastructural findings. Int J Gynecol Pathol 22:404–406
Heimann P, Devalck C, Debusscher C et al (1998) Alveolar soft-part sarcoma: further evidence by FISH for involvement of chromosome band 17q25. Genes Chromosomes Cancer 23:194–197
Hendrickson MR, Scheithauer BW (1986) Primitive neuroectodermal tumor of the endometrium: report of two cases, one with electron microscopic observations. Int J Gynecol Pathol 5:249–259
Herszkowicz L, dos Santos RG, Alves EV et al (2001) Benign neonatal hemangiomatosis with mucosal involvement. Arch Dermatol 137:828–829
Hines JF, Compton DM, Stacy CC et al (1990) Pure primary osteosarcoma of the ovary presenting as an extensively calcified adnexal mass: a case report and review of the literature. Gynecol Oncol 39:259–263
Holloway CL, Russell AH, Muto M et al (2007) Synovial cell sarcoma of the vulva: multimodality treatment incorporating preoperative external-beam radiation, hemivulvectomy, flap reconstruction, interstitial brachytherapy, and chemotherapy. Gynecol Oncol 104:253–256
Hoot AC, Russo P, Judkins AR et al (2004) Immunohistochemical analysis of hSNF5/INI1 distinguishes renal and extra-renal malignant rhabdoid tumors from other pediatric soft tissue tumors. Am J Surg Pathol 28:1485–1491
Hornick JL, Dal Cin P, Fletcher CD (2009) Loss of INI1 expression is characteristic of both conventional and proximal-type epithelioid sarcoma. Am J Surg Pathol 33:542–550
Hornick JL, Fletcher CD et al (2011) Pseudomyogenic hemangioendothelioma: a distinctive, often multicentric tumor with indolent behavior. Am J Surg Pathol 35:190–201
Horowitz IR, Copas P, Majmudar B (1995) Granular cell tumors of the vulva. Am J Obstet Gynecol 173:1710–1714
Howitt BE, Fletcher CDM (2016) Mammary-type myofibroblastoma: a clinicopathologic characterization in a series of 143 cases. Am J Surg Pathol 40:361–367
Hruban RH, Shiu MH, Senie RT et al (1990) Malignant peripheral nerve sheath tumors of the buttock and lower extremity. A study of 43 cases. Cancer 66:1253–1265
Huang HJ, Yamabe T, Tagawa H (1983) A solitary neurilemmoma of the clitoris. Gynecol Oncol 15:103–110
Inoue T, Kato H, Yoshikawa K et al (2004) Retroperitoneal schwannoma bearing at the right vaginal wall. J Obstet Gynaecol Res 30:454–457
Irving JA, Lerwill MF, Young RH (2005) Gastrointestinal stromal tumors metastatic to the ovary: a report of five cases. Am J Surg Pathol 29:920–926
Issa PY, Salem PA, Brihi E et al (1980) Eosinophilic granuloma with involvement of the female genitalia. Am J Obstet Gynecol 137:608–612
Iversen UM (1996) Two cases of benign vaginal rhabdomyoma. Case reports. APMIS 104:575–578
Iwasa Y, Fletcher CD (2004a) Distinctive prepubertal vulvar fibroma: a hitherto unrecognized mesenchymal tumor of prepubertal girls: analysis of 11 cases. Am J Surg Pathol 28:1601–1608
Iwasa Y, Fletcher CD (2004b) Cellular angiofibroma: clinicopathologic and immunohistochemical analysis of 51 cases. Am J Surg Pathol 28:1426–1435
Jagadha V, Srinivasan K, Panchacharam P (1985) Glomus tumor of the clitoris. N Y State J Med 85:611
Janinis J, Patriki M, Vini L et al (2003) The pharmacological treatment of aggressive fibromatosis: a systematic review. Ann Oncol 14:181–190
Jelinek JA, Stelzer KJ, Conrad E et al (2001) The efficacy of radiotherapy as postoperative treatment for desmoid tumors. Int J Radiat Oncol Biol Phys 50:121–125
Jylling AM, Jørgensen L, Hølund B (1999) Mucinous cystadenocarcinoma in combination with hemangiosarcoma in the ovary. Pathol Oncol Res 5:318–319
Kapadia SB, Norris HJ (1993) Rhabdomyoma of the vagina. Mod Pathol 6:75A
Kardhashi A, Assunta Deliso M, Renna A et al (2012) Benign granular cell tumor of the vulva: first report of multiple cases in a family. Gynecol Obstet Investig 73:341–348
Kargi HA, Özer E, Gökden N (1995) Inflammatory pseudotumor of the uterus: a case report. Tumori 81:454–456
Kasashima S, Minato H, Kobayashi M et al (2007) Alveolar soft part sarcoma of the endometrium with expression of CD10 and hormone receptors. APMIS 115:861–865
Katz VL, Askin FB, Bosch BD (1986) Glomus tumor of the vulva: a case report. Obstet Gynecol 67:43S–45S
Kawauchi S, Fukuda T, Miyamoto S et al (1998) Peripheral primitive neuroectodermal tumor of the ovary confirmed by CD99 immunostaining, karyotypic analysis, and RT-PCR for EWS/FLI-1 chimeric mRNA. Am J Surg Pathol 22:1417–1422
Kay S, Schneider V (1985) Reactive spindle cell nodule of the endocervix simulating uterine sarcoma. Int J Gynecol Pathol 4:255–257
Keel SB, Clement PB, Prat J et al (1998) Malignant schwannoma of the uterine cervix: a study of three cases. Int J Gynecol Pathol 17:223–230
Kelling K, Noack F, Altgassen C et al (2012) Primary metastasized extraskeletal Ewing sarcoma of the vulva: report of a case and review of the literature. Arch Gynecol Obstet 285:785–789
Kemmann E, Conrad P, Chen CK et al (1977) Pelvic neurilemmoma. Report of a case, electron microscopic studies, and review of the literature. Gynecol Oncol 5:387–395
Kenerson H, Folpe AL, Takayama TK et al (2007) Activation of the mTOR pathway in sporadic angiomyolipomas and other perivascular epithelioid cell neoplasms. Hum Pathol 38:1361–1371
Khosla D, Rai B, Patel FD et al (2014) Primitive neuroectodermal tumor of the uterine cervix diagnosed during pregnancy: a rare case with review of literature. J Obstet Gynaecol Res 40:878–882
Kim DH, Goldsmith HS, Quan SH et al (1971) Intra-abdominal desmoid tumor. Cancer 27:1041–1045
Kim MK, Huh SJ, Kim DY et al (1998) Secondary angiosarcoma following irradiation – case report and review of the literature. Radiat Med 16:55–60
Kim KJ, Jang BW, Lee SK et al (2004) A case of peripheral primitive neuroectodermal tumor of the ovary. Int J Gynecol Cancer 14:370–372
Kirkham YA, Yarbrough CM, Pippi Salle JL et al (2013) A rare case of inguinolabial lipoblastoma in a 13- month-old female. J Pediatr Urol 9:E64–E67
Kleinman GM, Young RH, Scully GM (1993) Primary neuroectodermal tumors of the ovary. A report of 25 cases. Am J Surg Pathol 17:764–778
Kobayashi T, Yamazaki T, Takahashi M (1999) Characteristic radiologic findings for cavernous hemangioma of the uterus. AJR Am J Roentgenol 172:1147–1148
Kohorn EL, Merino MJ, Goldenhersh M (1986) Vulvar pain and dyspareunia due to glomus tumor. Obstet Gynecol 67:41S–42S
Konrad EA, Meister P, Hübner G (1982) Extracardiac rhabdomyoma: report of different types with light microscopic and ultrastructural studies. Cancer 49:898–907
Kopolovic J, Weiss DB, Dolberg L et al (1987) Alveolar soft-part sarcoma of the female genital tract. Case report with ultrastructural findings. Arch Gynecol 240:125–129
Kruse AJ, Sep S, Slangen BF et al (2014) Angiosarcomas of primary gynecologic origin: a clinicopathologic review and quantitative analysis of survival. Int J Gynecol Cancer 24:4–12
Kryvenko ON, Gupta NS, Meier FA et al (2011) Anastomosing hemangioma of the genitourinary system: eight cases in the kidney and ovary with immunohistochemical and ultrastructural analysis. Am J Clin Pathol 136:450–457
Laartz BW, Cooper C, Degryse A et al (2005) Wolf in sheep’s clothing: advanced Kaposi sarcoma mimicking vulvar abscess. South Med J 98:475–477
Lack EE, Worsham GF, Callihan MD et al (1980) Granular cell tumor: a clinicopathologic study of 110 patients. J Surg Oncol 13:301–316
Ladanyi M, Lui MY, Antonescu CR et al (2001) The der(17)t(X;17)(p11;q25) of human alveolar soft part sarcoma fuses the TFE3 transcription factor gene to ASPL, a novel gene at 17q25. Oncogene 4:48–57
Ladanyi M, Antonescu CR, Drobnjak M et al (2002) The precrystalline cytoplasmic granules of alveolar soft part sarcoma contain monocarboxylate transporter 1 and CD147. Am J Pathol 160:1215–1221
Lambrou NC, Mirhashemi R, Wolfson A et al (2002) Malignant peripheral nerve sheath tumor of the vulva: a multimodal treatment approach. Gynecol Oncol 85:365–371
Laskin WB, Fetsch JF, Tavassoli FA (1997) Angiomyofibroblastoma of the female genital tract: analysis of 17 cases including a lipomatous variant. Hum Pathol 28:1046–1055
Laskin WB, Fetsch JF, Mostofi FK (1998) Angiomyofibroblastomalike tumor of the male genital tract: analysis of 11 cases with comparison to female angiomyofibroblastoma and spindle cell lipoma. Am J Surg Pathol 22:6–16
Laskin WB, Fetsch JF, Tavassoli FA (2001) Superficial cervicovaginal myofibroblastoma: fourteen cases of a distinctive mesenchymal tumor arising from the specialized subepithelial stroma of the lower female genital tract. Hum Pathol 32:715–725
Lawhead RA, Copeland LJ, Edwards CL (1985) Bilateral ovarian hemangiomas associated with diffuse abdominopelvic hemangiomatosis. Obstet Gynecol 65:597–599
Lawrence B, Perez-Atayde A, Hibbard MK et al (2000) TPM3-ALK and TPM4-ALK oncogenes in inflammatory myofibroblastic tumors. Am J Pathol 157:377–384
Leborgne F, Falconi LM (1980) Lymphangiosarcoma of the anterior abdominal wall: a case report. Cancer 46:1228–1230
Lee KM, Wah HK (2005) Primary Ewing’s sarcoma family of tumors arising from the broad ligament. Int J Gynecol Pathol 24:377–381
Lee JC, Li CF, Huang HY, Zhu MJ et al (2017) ALK oncoproteins in atypical inflammatory myofibroblastic tumours: novel RRBP1-ALK fusions in epithelioid inflammatory myofibroblastic sarcoma. J Pathol 241:316–323
LeMaire WJ, Kreiss C, Commodore A et al (2002) Neurilemmoma: an unusual benign tumor of the cervix. Alaska Med 44:63–65
Levavi H, Sabah G, Kaplan B et al (2006) Granular cell tumor of the vulva: six new cases. Arch Gynecol Obstet 273:246–249
Lieb SM, Gallousis S, Freedman H (1979) Granular cell myoblastoma of the vulva. Gynecol Oncol 8:12–20
Lieberman PH, Brennan MF, Kimmel M et al (1989) Alveolar soft-part sarcoma. A clinico-pathologic study of half a century. Cancer 63:1–13
Lifschitz-Mercer B, Leider-Trejo L, Messer G et al (1998) Primary angiosarcoma of the ovary: a clinicopathologic, immunohistochemical and electron microscopic study. Pathol Res Pract 194:183–187
Lin GY, Sun X, Badve S (2002) Pathologic quiz case. Vaginal wall mass in a 47-year-old woman. Vaginal rhabdomyoma. Arch Pathol Lab Med 126:1241–1242
Liu Y, Guo S, Wang L et al (2016) Uterine angiosarcoma: a case report and literature review. Int J Gynecol Pathol 35:264–268
Long SR, Whitfeld MJ, Eades C et al (1996) Bacillary angiomatosis of the cervix and vulva in a patient with AIDS. Obstet Gynecol 88:709–711
Lovly CM, Gupta A, Lipson D et al (2014) Inflammatory myofibroblastic tumors harbor multiple potentially actionable kinase fusions. Cancer Discov 4:889–895
Maddox JC, Evans HL (1981) Angiosarcoma of skin and soft tissue: a study of forty-four cases. Cancer 48:1907–1921
Maggiani F, Debiec-Rychter M, Vanbockrijck M et al (2007) Cellular angiofibroma: another mesenchymal tumour with 13q14 involvement, suggesting a link with spindle cell lipoma and (extra)-mammary myofibroblastoma. Histopathology 51:410–412
Maglione MA, Tricarico OD, Calandria L (2002) Malignant peripheral nerve sheath tumor of the vulva. A case report. J Reprod Med 47:721–724
Magro G, Caltabiano R, Kacerovská D et al (2012a) Vulvovaginal myofibroblastoma: expanding the morphological and immunohistochemical spectrum. A clinicopathologic study of 10 cases. Hum Pathol 43:243–253
Magro G, Righi A, Casorzo L et al (2012b) Mammary and vaginal myofibroblastomas are genetically related lesions: fluorescence in situ hybridization analysis shows deletion of the 13q14 region. HumPathol 43:1887–1893
Magro G, Righi A, Caltabiano R et al (2014) Vulvovaginal angiomyofibroblastomas: morphologic, immunohistochemical, and fluorescence in situ hybridization analysis for deletion of 13q14 region. Hum Pathol 45:1647–1655
Maire G, Martin L, Michalak-Provost S et al (2002) Fusion of COL1A1 exon 29 with PDGFB exon 2 in a der(22)t(17;22) in a pediatric giant cell fibroblastoma with a pigmented Bednar tumor component. Evidence for age-related chromosomal pattern in dermatofibrosarcoma protuberans and related tumors. Cancer Genet Cytogenet 134:156–161
Majmudar B, Castellano PZ, Wilson RW et al (1990) Granular cell tumors of the vulva. J Reprod Med 35:1008–1014
Majmudar B, Ghanee N, Horowitz IR et al (1998) Uterine arteriovenous malformation necessitating hysterectomy with bilateral salpingo-oophorectomy in a young pregnant patient. Arch Pathol Lab Med 122:842–845
Malinowska I, Kwiatkowski DJ, Weiss S et al (2012) Perivascular epithelioid cell tumors (PEComas) harboring TFE3 gene rearrangements lack the TSC2 alterations characteristic of conventional PEComas: further evidence for a biological distinction. Am J Surg Pathol 36:783–784
Manetta A, Abt AB, Mamourian AC et al (1989) Pelvic fibromatosis: case report and review of literature. Gynecol Oncol 32:91–94
Manson CM, Hirsch PJ, Coyne JD (1995) Post-operative spindle cell nodule of the vulva. Histopathology 26:571–574
Mariani A, Nascimento AG, Webb MJ et al (2000) Surgical management of desmoid tumors of the female pelvis. J Am Coll Surg 191:175–183
Marino-Enriquez A, Wang WL, Roy A et al (2011) Epithelioid inflammatory myofibroblastic sarcoma: an aggressive intra-abdominal variant of inflammatory myofibroblastic tumor with nuclear membrane or perinuclear ALK. Am J Surg Pathol 35:135–144
Masoura S, Kourtis A, Kalogiannidis I et al (2012) Primary primitive neuroectodermal tumor of the cervix confirmed with molecular analysis in a 23-year-old woman: a case report. Pathol Res Pract 20(8):245–249
McAdam JA, Stewart F, Reid R (1998) Vaginal epithelioid angiosarcoma. J Clin Pathol 51:928–930
McArthur G (2006) Dermatofibrosarcoma protuberans: recent clinical progress. Ann Surg Oncol 14:2876–2886
McCluggage WG, Smith JH (2011) Reactive fibroblastic and myofibroblastic proliferation of the vulva (Cyclist’s nodule): a hitherto poorly described vulvar lesion occurring in cyclists. Am J Surg Pathol 35:110–114
McCluggage WG, Young RH (2006) Paraganglioma of the ovary: report of three cases of a rare ovarian neoplasm, including two exhibiting inhibin positivity. Am J Surg Pathol 30:600–605
McCluggage WG, Patterson A, Maxwell P (2000) Aggressive angiomyxoma of pelvic parts exhibits oestrogen and progesterone receptor positivity. J Clin Pathol 53:603–605
McCluggage WG, Perenyei M, Irwin ST (2002) Recurrent cellular angiofibroma of the vulva. J Clin Pathol 55:477–479
McCluggage WG, Jamieson T, Dobbs SP et al (2006) Aggressive angiomyxoma of the vulva: dramatic response to gonadotropin-releasing hormone agonist therapy. Gynecol Oncol 100:623–625
McCluggage WG, Sumathi VP, Nucci MR et al (2007) Ewing family of tumours involving the vulva and vagina: report of a series of four cases. J Clin Pathol 60:674–680
McCluggage WG, Nielsen GP, Young RH (2008) Massive vulvar edema secondary to obesity and immobilization: a potential mimic of aggressive angiomyxoma. J Gynecol Pathol 27:447–452
McCluggage WG, Connolly L, McBride HA (2010) HMGA2 is a sensitive but not specific immunohistochemical marker of vulvovaginal aggressive angiomyxoma. Am J Surg Pathol 34:1037–1042
McCluggage WG, Longacre TA, Fisher C (2013) Myogenin expression in vulvovaginal spindle cell lesions: analysis of a series of cases with an emphasis on diagnostic pitfalls. Histopathology 63:545–550
McDonald AG, Dal Cin P, Ganguly A et al (2011) Liposarcoma arising in uterine lipoleiomyoma: a report of 3 cases and review of the literature. Am J Surg Pathol 35:221–227
McPeak CJ, Cruz T, Nicastri AD (1967) Dermatofibrosarcoma protuberans: an analysis of 86 cases—five with metastasis. Ann Surg 166:803–816
Medeiros F, Erickson-Johnson MR, Keeney GL et al (2007) Frequency and characterization of HMGA2 and HMGA1 rearrangements in mesenchymal tumors of the lower genital tract. Genes Chromosomes Cancer 46:981–990
Mendez LE, Joy S, Angioli R et al (1999) Primary uterine angiosarcoma. Gynecol Oncol 75:272–276
Mentzel T, Beham A, Katenkamp D et al (1998) Fibrosarcomatous (“high-grade”) dermatofibrosarcoma protuberans: clinicopathologic and immunohistochemical study of a series of 41 cases with emphasis on prognostic significance. Am J Surg Pathol 22:576–587
Merker VL, Esparza S, Smith MJ et al (2012) Clinical features of schwannomatosis: a retrospective analysis of 87 patients. Oncologist 17:1317–1322
Miettinen M, Virtanen I, Damjanov I (1985) Coexpression of keratin and vimentin in epithelioid sarcoma. Am J Surg Pathol 9:460–462
Miettinen M, Fanburg-Smith JC, Virolainen M et al (1999) Epithelioid sarcoma: an immunohistochemical analysis of 112 classical and variant cases and a discussion of the differential diagnosis. Hum Pathol 30:934–942
Miettinen M, Sobin LH, Lasota J (2009) Gastrointestinal stromal tumors presenting as omental masses—a clinicopathologic analysis of 95 cases. Am J Surg Pathol 33:1267–1275
Miettinen M, McCue PA, Sarlomo-Rikala M et al (2015) Sox10 – a marker for not only schwannian and melanocytic neoplasms but also myoepithelial cell tumors of soft tissue: a systematic analysis of 5134 tumors. Am J Surg Pathol 39:826–835
Mirkovic J, Fletcher CDM (2015) Lipoblastoma-like tumor of the vulva. Further characterization in 8 new cases. Am J Surg Pathol 39:1290–1295
Mitsuhashi A, Nagai Y, Suzuka K et al (2006) Primary synovial sarcoma in fallopian tube: case report and literature review. Int J Gynecol Pathol 26:34–37
Modena P, Lualdi E, Facchinetti F et al (2005) SMARCB1/INI1 tumor suppressor gene is frequently inactivated in epithelioid sarcomas. Cancer Res 65:4012–4019
Mohajeri A, Tayebwa J, Collin A et al (2013) Comprehensive genetic analysis identifies a pathognomonic NAB2/STAT6 fusion gene, nonrandom secondary genomic imbalances, and a characteristic gene expression profile in solitary fibrous tumor. Genes Chromosomes Cancer 52:873–886
Montgomery EA, Meis JM (1991) Nodular fasciitis. Its morphologic spectrum and immunohistochemical profile. Am J Surg Pathol 15:942–948
Montgomery EA, Shuster DD, Burkart AL et al (2006) Inflammatory myofibroblastic tumors of the urinary tract: a clinicopathologic study of 46 cases, including a malignant example inflammatory fibrosarcoma and a subset associated with high-grade urothelial carcinoma. Am J Surg Pathol 30:1502–1512
Moreno-Rodríguez M, Pérez-Sicilia M, Delinois R (1999) Lipoma of the endocervix. Histopathology 35:483–484
Morgan MA, Moutos DM, Pippitt CH Jr et al (1989) Vaginal and bladder angiosarcoma after therapeutic irradiation. South Med J 82:1434–1436
Morrel B, Mulder AF, Chadha S et al (1993) Angiosarcoma of the uterus following radiotherapy for squamous cell carcinoma of the cervix. Eur J Obstet Gynecol Reprod Biol 49:193–197
Moscovic EA, Azar HA (1967) Multiple granular cell tumors (“myoblastomas”). Case report with electron microscopic observations and review of the literature. Cancer 20:2032–2047
Mosquera JM, Fletcher CD (2009) Expanding the spectrum of malignant progression in solitary fibrous tumors: a study of 8 cases with a discrete anaplastic component – is this dedifferentiated SFT? Am J Surg Pathol 33:1314–1321
Murray J, Fox H (1991) Rosai-Dorfman disease of the uterine cervix. Int J Gynecol Pathol 10:209–213
Namizato CS, Muriel-Cueto P, Baez-Perez JM et al (2008) Chondrosarcoma of the uterus: case report and literature review. Arch Gynecol Obstet 278:369–372
Němejcová K, Dundr P, Krajsová I (2016) Clear cell sarcoma of the vulva. A case report. Cesk Patol 52:215–217
Nielsen GP, Young RH (1997) Fibromatosis of soft tissue type involving the female genital tract: a report of two cases. Int J Gynecol Pathol 16:383–386
Nielsen GP, Young RH (2001) Mesenchymal tumors and tumor-like lesions of the female genital tract: a selective review with emphasis on recently described entities. Int J Gynecol Pathol 20:105–127
Nielsen GP, Oliva E, Young RH et al (1995) Alveolar soft-part sarcoma of the female genital tract: a report of nine cases and review of the literature. Int J Gynecol Pathol 14:283–292
Nielsen GP, Rosenberg AE, Young RH et al (1996a) Angiomyofibroblastoma of the vulva and vagina. Mod Pathol 9:284–291
Nielsen GP, Shaw PA, Rosenberg AE et al (1996b) Synovial sarcoma of the vulva: a report of two cases. Mod Pathol 9:970–974
Nielsen GP, Young RH, Dickersin GR et al (1997a) Angiomyofibroblastoma of the vulva with sarcomatous transformation (“angiomyofibrosarcoma”). Am J Surg Pathol 21:1104–1108
Nielsen GP, Young RH, Prat J et al (1997b) Primary angiosarcoma of the ovary: a report of seven cases and review of the literature. Int J Gynecol Pathol 16:378–382
Nirenberg A, Östör AG, Slavin J et al (1995) Primary vulvar sarcomas. Int J Gynecol Pathol 14:55–62
Nishimura K, Sugao H, Sato K et al (1991) Neurofibroma of the clitoris. A case report. Urol Int 46:109–111
Nolan NP, Gaffney EF (1990) Alveolar soft part sarcoma of the uterus. Histopathology 16:97–99
Nonaka D, Chiriboga L, Rubin BP (2008) Sox10: a pan-schwannian and melanocytic marker. Am J Surg Pathol 32:1291–1298
Nucci MR, Fletcher CD (1998) Liposarcoma (atypical lipomatous tumor) of the vulva: a clinicopathologic study of six cases. Int J Gynecol Pathol 17:17–23
Nucci MR, Granter SR, Fletcher CD (1997) Cellular angiofibroma: a benign neoplasm distinct from angiomyofibroblastoma and spindle cell lipoma. Am J Surg Pathol 21:636–644
Nucci MR, Krausz T, Lifschitz-Mercer B et al (1998) Angiosarcoma of the ovary: clinicopathologic and immunohistochemical analysis of four cases with a broad morphologic spectrum. Am J Surg Pathol 22:620–630
Nucci MR, Weremowicz S, Neskey DM et al (2001) Chromosomal translocation t(8;12) induces aberrant HMGIC expression in aggressive angiomyxoma of the vulva. Genes Chromosomes Cancer 32:172–176
Nucci MR, Castrillon DH, Bai H et al (2003) Biomarkers in diagnostic obstetric and gynecologic pathology: a review. Adv Anat Pathol 10:55–68
O’Connell JX, Young RH, Nielsen GP et al (1997) Nodular fasciitis of the vulva: a study of six cases and literature review. Int J Gynecol Pathol 16:117–123
O’Toole RV, Tuttle SE, Lucas JG et al (1985) Alveolar soft part sarcoma of the vagina: an immunohistochemical and electron microscopic study. Int J Gynecol Pathol 4:258–265
Oda Y, Tsuneyoshi M (2006) Extrarenal rhabdoid tumors of soft tissue: clinicopathological and molecular genetic review and distinction from other soft-tissue sarcomas with rhabdoid features. Pathol Int 56:287–295
Oda Y, Hashimoto H, Tsuneyoshi M et al (1993) Survival in synovial sarcoma. A multivariate study of prognostic factors with special emphasis on the comparison between early death and long-term survival. Am J Surg Pathol 17:35–44
Olawaiye AB, Morgan JA, Goodman A et al (2008) Epithelioid angiosarcoma of the uterus: a review of management. Arch Gynecol Obstet 278:401–404
Ongkasuwan C, Taylor JE, Tang CK et al (1982) Angiosarcomas of the uterus and ovary: clinicopathologic report. Cancer 49:1469–1475
Ordi J, Stamatakos MD, Tavassoli FA (1997) Pure pleomorphic rhabdomyosarcomas of the uterus. Int J Gynecol Pathol 16:369–377
Ordóñez NG (1999) Alveolar soft part sarcoma: a review and update. Adv Anat Pathol 6:125–139
Ostwal V, Rekhi B, Noronha V et al (2012) Primitive neuroectodermal tumor of ovary in a young lady, confirmed with molecular and cytogenetic results – a rare case report with a diagnostic and therapeutic challenge. Pathol Oncol Res 18:1101–1106
Outwater EK, Marchetto BE, Wagner BJ et al (1999) Aggressive angiomyxoma: findings on CT and MR imaging. AJR 172:435–438
Paik HH, Komorowski R (1976) Hemangiosarcoma of the abdominal wall following irradiation therapy of endometrial carcinoma. Am J Clin Pathol 66:810–814
Park JY, Lee S, Kang HJ et al (2007) Primary Ewing’s sarcoma-primitive neuroectodermal tumor of the uterus: a case report and literature review. Gynecol Oncol 106:427–432
Parra-Herran C, Quick CM, Howitt BE et al (2015) Inflammatory myofibroblastic tumor of the uterus: clinical and pathologic review of 10 cases including a subset with aggressive clinical course. Am J Surg Pathol 39:157–168
Pauwels P, Ambros P, Hattinger C et al (2000) Peripheral primitive neuroectodermal tumour of the cervix. Virchows Arch 436:68–73
Pelosi G, Luzzatto F, Landoni F et al (2007) Poorly differentiated synovial sarcoma of the vagina: first reported case with immunohistochemical, molecular and ultrastructural data. Histopathology 50:808–810
Penel N, Le Cesne A, Bui BN et al (2011) Imatinib for progressive and recurrent aggressive fibromatosis (desmoid tumors): an FNCLCC/French Sarcoma Group phase II trial with a long-term follow-up. Ann Oncol 22:452–457
Perrone T, Swanson PE, Twiggs L et al (1989) Malignant rhabdoid tumor of the vulva: is distinction from epithelioid sarcoma possible? Am J Surg Pathol 13:848–858
Petković M, Zamolo G, Muhvić D et al (2002) The first report of extraosseous Ewing’s sarcoma in the rectovaginal septum. Tumori 88:345–346
Pichler Sekulic S, Sekulic M (2016) Nodular fasciitis of the vulva: a challenging histopathologic diagnosis supported by the detection of USP6 gene rearrangement. APMIS 124:534–537
Pillay K, Essa AS, Chetty R (2001) Borderline serous cystadenocarcinoma with coexistent angiosarcoma: an unusual form of ovarian carcinosarcoma. Int J Surg Pathol 9:317–321
Piver MS, Tsukada Y, Barlow J (1972) Epithelioid sarcoma of the vulva. Obstet Gynecol 40:839–842
Platt JS, Rogers SJ, Flynn EA et al (1999) Primary angiosarcoma of the ovary: a case report and review of the literature. Gynecol Oncol 73:443–446
Prempree T, Tang CK, Hatef A et al (1983) Angiosarcoma of the vagina: a clinicopathologic report. A reappraisal of the radiation treatment of angiosarcomas of the female genital tract. Cancer 51:618–622
Pressoir R, Chung EB (1980) Granular cell tumor in black patients. J Natl Med Assoc 72:1171–1175
Prieto-Granada CN, Wiesner T, Messina JL et al (2016) Loss of H3K27me3 expression is a highly sensitive marker for sporadic and radiation-induced MPNST. Am J Surg Pathol 40:479–489
Proppe KH, Scully RE, Rosai J (1984) Postoperative spindle cell nodules of genitourinary tract resembling sarcomas. Am J Surg Pathol 8:101–108
Prus D, Rosenberg AE, Blumenfeld A et al (1997) Infantile hemangioendothelioma of the ovary: a monodermal teratoma or a neoplasm of ovarian somatic cells? Am J Surg Pathol 21:1231–1235
Rabban JT, Zaloudek CJ, Shekitka KM et al (2005) Inflammatory myofibroblastic tumor of the uterus: a clinicopathologic study of 6 cases emphasizing distinction from aggressive mesenchymal tumors. Am J Surg Pathol 29:1348–1355
Radig K, Buhtz P, Roessner A (1998) Alveolar soft part sarcoma of the uterine corpus. Report of two cases and review of the literature. Pathol Res Pract 194:59–63
Rajah SB, Moodley J, Pudifin DJ et al (1990) Kaposi’s sarcoma associated with acquired immunodeficiency syndrome presenting as a vulvar papilloma. A case report. S Afr Med J 77:585–586
Ramos PC, Kapp DS, Longacre TA et al (2000) Malignant granular cell tumor of the vulva in a 17-year-old: case report and literature review. Int J Gynecol Cancer 10:429–434
Rao Q, Cheng L, Xia QY et al (2013) Cathepsin K expression in a wide spectrum of perivascular epithelioid cell neoplasms (PEComas): a clinicopathological study emphasizing extrarenal PEComas. Histopathology 62:642–650
Reitamo JJ, Häyry P, Nykyri E et al (1982) The desmoid tumor. I. Incidence, sex-, age-, and anatomic distribution in the Finnish population. Am J Clin Pathol 77:665–673
Rezvani FF (1997) Vaginal cavernous hemangioma in pregnancy. Obstet Gynecol 89:824–825
Riccardi VM (1981) Von Recklinghausen neurofibromatosis. N Engl J Med 305:1617–1627
Rink RC, Mitchell ME (1983) Genitourinary neurofibromatosis in childhood. J Urol 130:1176–1179
Robertson AJ, McIntosh W, Lamont P et al (1981) Malignant granular cell tumor (myoblastoma) of the vulva: report of a case and review of the literature. Histopathology 5:69–79
Robinson DR, Wu YM, Kalyana-Sundaram S et al (2013) Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencing. Nat Genet 45:180–185
Roma AA, Yang B, Senior ME et al (2005) TFE3 immunoreactivity in alveolar soft part sarcoma of the uterine cervix: case report. Int J Gynecol Pathol 24:131–135
Roses DF, Valensi Q, LaTrenta G et al (1986) Surgical treatment of dermatofibrosarcoma protuberans. Surg Gynecol Obstet 162:449–452
Saha SC, Dogra M, Malhotra S (1993) Pelvic plexiform neurofibroma—an obstetric dilemma. Int J Gynecol Obstet 43:61–62
Sahin AA, Silva EG, Ordonez NG (1989) Alveolar soft part sarcoma of the uterine cervix. Mod Pathol 2:676–680
Santos LD, Currie BG, Killingsworth MC (2001) Case report: plexiform schwannoma of the vulva. Pathology 33:526–531
Savargaonkar PR, Wells S, Graham I et al (1994) Ovarian haemangiomas and stromal luteinization. Histopathology 25:185–188
Scanlon R, Kelehan P, Flannelly G et al (2003) Ischemic fasciitis: an unusual vulvovaginal spindle cell lesion. Int J Gynecol Pathol 23:65–67
Schaefer IM, Fletcher CD, Hornick JL et al (2016) Loss of H3K27 trimethylation distinguishes malignant peripheral nerve sheath tumors from histologic mimics. Mod Pathol 29:4–13
Schammel DP, Tavassoli FA (1998) Uterine angiosarcoma: a morphologic and immunohistochemical study of four cases. Am J Surg Pathol 22:246–250
Scherr GR, d’Ablaing G 3rd, Ouzounian JG (1994) Peripheral primitive neuroectodermal tumor of the vulva. Gynecol Oncol 54:254–258
Schoolmeester JK, Fritchie KJ (2015) Genital soft tissue tumors. J Cutan Pathol 42:441–451
Schoolmeester JK, Lastra RR (2015) Granular cell tumors overexpress TFE3 without corollary gene rearrangement. Hum Pathol 46:1242–1243
Schoolmeester JK, Sukov WR (2017) ALK-rearranged inflammatory myofibroblastic tumor of the placenta, with observations on site of origin. Int J Gynecol Pathol 36:228–229
Schoolmeester JK, Howitt BE, Hirsch MS et al (2014) Perivascular epithelioid cell neoplasm (PEComa) of the gynecologic tract: clinicopathologic and immunohistochemical characterization of 16 cases. Am J Surg Pathol 38:176–188
Schoolmeester JK, Dao LN, Sukov WR (2015) TFE3 translocation-associated perivascular epithelioid cell neoplasm (PEComa) of the gynecologic tract: morphology, immunophenotype, differential diagnosis. Am J Surg Pathol 39:394–404
Schoolmeester JK, Carlson J, Keeney GL et al (2017) Alveolar soft part sarcoma of the female genital tract: a morphologic, Immunohistochemical, and molecular cytogenetic study of 10 cases with emphasis on its distinction from morphologic mimics. Am J Surg Pathol 41:622–632
Schreiber MM (1963) Vulvar von Recklinghausen’s disease. Arch Dermatol 88:320–321
Schwartz BM, Kuo DY, Goldberg GL (1999) Dermatofibrosarcoma protuberans of the vulva: a rare tumor presenting during pregnancy in a teenager. J Lower Genital Tract Dis 3:139–142
Schwartz PE, Hui P, McCarthy SJ (2014) Hormonal therapy for aggressive angiomyxoma: a case report and proposed management algorithm. J Low Genit Tract Dis 18:E55–E61
Sheth A, Terzic M, Arsenovic N (2011) Vulvar hibernoma. Indian J Pathol Microbiol 54:817–818
Shimizu A, O’Brien KP, Sjöblom T et al (1999) The dermatofibrosarcoma protuberans-associated collagen type Ialpha1/platelet-derived growth factor (PDGF) B-chain fusion gene generates a transforming protein that is processed to functional PDGF-BB. Cancer Res 59:3719–3723
Shin C, Low I, Ng D et al (2016) USP6 gene rearrangement in nodular fasciitis and histological mimics. Histopathology 69:784–791
Shintaku M, Fukushima A (2006) Inflammatory myofibroblastic tumor of the uterus with prominent myxoid change. Pathol Int 56:625–628
Siassi RM, Papadopoulos T, Matzel KE (1999) Metastasizing aggressive angiomyxoma. N Engl J Med 341:1772
Simon NL, Mazur MT, Shingleton HM (1985) Pelvic fibromatosis: an unusual gynecologic tumor. Obstet Gynecol 65:767–769
Simpson KW, Albores-Saavedra J (2007) HMB-45 reactivity in conventional uterine leiomyosarcomas. Am J Surg Pathol 31:95–98
Sims SM, Stinson K, McLean FW et al (2012) Angiomyofibroblastoma of the vulva: a case report of a pedunculated variant and review of the literature. J Low Genit Tract Dis 16:149–154
Sinkre P, Albores-Saavedra J, Miller DS et al (2000) Endometrial endometrioid carcinomas associated with Ewing sarcoma/peripheral primitive neuroectodermal tumor. Int J Gynecol Pathol 19:127–132
Sirvent N, Maire G, Pedeutour F (2003) Genetics of dermatofibrosarcoma protuberans family of tumors: from ring chromosome to tyrosine kinase inhibitor treatment. Genes Chromosomes Cancer 37:1–19
Skálová A, Michal M, Hušek K et al (1993) Aggressive angiomyxoma of the pelvioperineal region. Immunohistochemical and ultrastructural study of seven cases. Am J Dermatopathol 15:446–451
Smith CJ, Ferrier AJ, Russell P et al (2005) Primary synovial sarcoma of the ovary: first reported case. Pathology 37:385–387
Smith HG, Thway K, Messiou C et al (2016) Selective marginal resections in the management of aggressive angiomyxomas. J Surg Oncol 114:828–832
Snijders-Keilholz A, Ewing P, Seynaeve C et al (2005) Primitive neuroectodermal tumor of the cervix uteri: a case report – changing concepts in therapy. Gynecol Oncol 98:516–519
Snow SN, Gordon EM, Larson PO et al (2004) Dermatofibrosarcoma protuberans: a report on 29 patients treated by Mohs micrographic surgery with long-term follow-up and review of the literature. Cancer 101:28–38
Sobottka Ventura AC, Remonda L, Mojon DS (2001) Intermittent visual loss and exophthalmos due to the blue rubber bleb nevus syndrome. Am J Ophthalmol 132:132–135
Sonobe H, Ro JY, Ramos M et al (1994) Glomus tumor of the female external genitalia: a report of two cases. Int J Gynecol Pathol 13:359–364
Sordillo PP, Helson L, Hajdu SI et al (1981) Malignant schwannoma – clinical characteristics, survival, and response to therapy. Cancer 47:2503–2509
Stacchiotti S, Negri T, Zaffaroni N et al (2011) Sunitinib in advanced alveolar soft part sarcoma: evidence of a direct antitumor effect. Ann Oncol 22:1682–1690
Starbuck KD, Drake RD, Budd GT et al (2016) Treatment of advanced malignant uterine perivascular epithelioid cell tumor with mTOR inhibitors: single-institution experience and review of the literature. Anticancer Res 36:6161–6164
Steeper TA, Rosai J (1983) Aggressive angiomyxoma of the female pelvis and perineum. Report of nine cases of a distinctive type of gynecologic soft-tissue neoplasm. Am J Surg Pathol 7:463–475
Stratakis CA, Kirschner LS, Carney JA (2001) Clinical and molecular features of the Carney complex: diagnostic criteria and recommendations for patient evaluation. J Clin Endocrinol Metab 86:4041–4046
Strayer SA, Yum MN, Sutton GP (1992) Epithelioid hemangioendothelioma of the clitoris: a case report with immunohistochemical and ultrastructural findings. Int J Gynecol Pathol 11:234–239
Strickland KC, Nucci MR, Esselen KM et al (2016) Solitary fibrous tumor of the uterus presenting with lung metastases: a case report. Int J Gynecol Pathol 35:25–29
Strong EW, McDivitt RW, Brasfield RD (1970) Granular cell myoblastoma. Cancer 25:415–422
Suarez Vilela D, Gimenez Pizarro A, Rio Suarez M (1990) Vaginal rhabdomyoma and adenosis. Histopathology 16:393–394
Suleiman M, Duc C, Ritz S et al (2006) Pelvic excision of large aggressive angiomyxoma in a woman: irradiation for recurrent disease. Int J Gynecol Cancer 16:356–360
Sumathi VP, Fisher C, Williams A et al (2011) Synovial sarcoma of the vulva and vagina: a clinicopathologic and molecular genetic study of 4 cases. Int J Gynecol Pathol 30:84–91
Sutphen R, Galán-Goméz E, Kousseff BG (1995) Clitoromegaly in neurofibromatosis. Am J Med Genet 55:325–330
Taïeb S, Cabaret V, Bonodeau F et al (1998) MRI of primitive neuroectodermal tumor of the uterus. J Comput Assist Tomogr 22:896–898
Takeuchi K, Murata K, Funaki K et al (2000) Liposarcoma of the uterine cervix: case report. Eur J Gynaecol Oncol 21:290–291
Talerman A, Auerbach WM, van Meurs AJ (1981) Primary chondrosarcoma of the ovary. Histopathology 5:319–324
Tallini G, Price FV, Carcangiu ML (1993) Epithelioid angiosarcoma arising in uterine leiomyomas. Am J Clin Pathol 100:514–518
Tan GW, Lim-Tan SK, Salmon YM (1989) Epithelioid sarcoma of the vulva. Singap Med J 30:308–310
Terada KY, Schmidt RW, Roberts JA (1988) Malignant schwannoma of the vulva. A case report. J Reprod Med 33:969–972
Thanner F, Suetterlin M, Kenn W et al (2001) Pregnancy-associated diffuse cavernous hemangioma of the uterus. Acta Obstet Gynecol Scand 80:1150–1151
Tiltman AJ, Duffield MS (1996) Postpartum microneuromas of the uterine cervix. Histopathology 28:153–156
Tjalma WA, Hauben EI, Deprez SM et al (1999) Epithelioid sarcoma of the vulva. Gynecol Oncol 73:160–164
Tohya T, Katabuchi H, Fukuma K et al (1991) Angiosarcoma of the vagina. A light and electron microscopy study. Acta Obstet Gynecol Scand 70:169–172
Tsao AS, Roth LM, Sandler A et al (2001) Cervical primitive neuroectodermal tumor. Gynecol Oncol 83:138–142
Tsuji T, Yoshinaga M, Inomoto Y et al (2007) Aggressive angiomyxoma of the vulva with a sole t(5;8)(p15;q22) chromosome change. Int J Gynecol Pathol 26:494–496
Tsukasaki N, Mori T, Yasukawa S et al (2016) Primary osteosarcoma of the uterine corpus: a case report. J Obstet Gynaecol Res 42:1604–1608
Tunitsky-Bitton E, Uy-Kroh MJ, Michener C et al (2015) Primary Ewing sarcoma presenting as a vulvar mass in an adolescent: case report and review of literature. J Pediatr Adolesc Gynecol 28:e179–e183
Ueda M, Okamoto Y, Ueki M (1996) A pelvic retroperitoneal schwannoma arising in the right paracolpium. Gynecol Oncol 60:480–483
Uzunlar AK, Yilmaz F, Kilinç N et al (2002) Cavernous hemangioma of the uterus (a case report). Eur J Gynaecol Oncol 23:72–73
Vallat-Decouvelaere A-V, Dry SM, Fletcher CD (1998) Atypical and malignant solitary fibrous tumors in extrathoracic locations: evidence of their comparability to intra-thoracic tumors. Am J Surg Pathol 22:1501–1511
van de Rijn M, Barr FG, Xiong QB et al (1999) Poorly differentiated synovial sarcoma: an analysis of clinical, pathologic, and molecular genetic features. Am J Surg Pathol 23:106–112
Van Leeuwen J, van der Putten HW, Demeyere TB et al (2011) Paraganglioma of the uterus: a case report and review of literature. Gynecol Oncol 121:418–419
Vang R, Kempson RL (2002) Perivascular epithelioid cell tumor (‘PEComa’) of the uterus: a subset of HMB-45-positive epithelioid mesenchymal neoplasms with an uncertain relationship to pure smooth muscle tumors. Am J Surg Pathol 26:1–13
Vang R, Connelly JH, Hammill HA et al (2000a) Vulvar hypertrophy with lymphedema. A mimicker of aggressive angiomyxoma. Arch Pathol Lab Med 124:1697–1699
Vang R, Taubenberger JK, Mannion CM et al (2000b) Primary vulvar and vaginal extraosseous Ewing’s sarcoma/peripheral neuroectodermal tumor: diagnostic confirmation with CD99 immunostaining and reverse transcriptase-polymerase chain reaction. Int J Gynecol Pathol 19:103–109
Vanni R, Faa G, Dettori T et al (2000) A case of dermatofibrosarcoma protuberans of the vulva with a COL1A1/PDGFB fusion identical to a case of giant cell fibroblastoma. Virchows Arch 437:95–100
Vargas SO, Kozakewich HP, Boyd TK et al (2005) Childhood asymmetric labium majus enlargement: mimicking a neoplasm. Am J Surg Pathol 29:1007–1016
Varghese L, Arnesen M, Boente M (2006) Primitive neuroectodermal tumor of the uterus: a case report and review of literature. Int J Gynecol Pathol 25:373–377
Vyas V, Rammah AM, Ashebu SD et al (2006) A case report of primary osteosarcoma of the ovary. Int J Gynecol Cancer 16(Suppl 1):349–352
Wakami K, Tateyama H, Kawashima H et al (2005) Solitary fibrous tumor of the uterus producing high-molecular-weight insulin-like growth factor II and associated with hypoglycemia. Int J Gynecol Pathol 24:79–84
Wanebo JE, Malik JM, VandenBerg SR et al (1993) Malignant peripheral nerve sheath tumors: a clinicopathologic study of 28 cases. Cancer 71:1247–1253
Webb MJ, Symmonds RE, Weiland LH (1974) Malignant fibrous histiocytoma of the vagina. Am J Obstet Gynecol 119:190–192
Wei EX, Albores-Saavedra J, Fowler MR (2005) Plexiform neurofibroma of the uterine cervix: a case report and review of the literature. Arch Pathol Lab Med 129:783–786
Weissman A, Talmon R, Jakobi P (1993) Cavernous hemangioma of the uterus in a pregnant woman. Obstet Gynecol 81:825–827
White J, Chan YF (1994) Aggressive angiomyxoma of the vulva in an 11-year-old girl. Pediatr Pathol 14:27–37
White W, Shiu MH, Rosenblum MK et al (1990) Cellular schwannoma. A clinicopathologic study of 57 patients and 58 tumors. Cancer 66:1266–1275
White BE, Kaplan A, Lopez-Terrada DH et al (2008) Monophasic synovial sarcoma arising in the vulva: a case report and review of the literature. Arch Pathol Lab Med 132:698–702
Wilcken N, Tattersall MH (1991) Endocrine therapy for desmoid tumors. Cancer 68:1384–1388
Wingen CB, Pauwels PA, Debiec-Rychter M et al (2005) Uterine gastrointestinal stromal tumour (GIST). Gynecol Oncol 97:970–972
Witkin GB, Askin FB, Geratz JD et al (1987) Angiosarcoma of the uterus: a light microscopic, immunohistochemical, and ultrastructural study. Int J Gynecol Pathol 6:176–184
Wolber RA, Talerman A, Wilkinson EJ et al (1991) Vulvar granular cell tumors with pseudocarcinomatous hyperplasia: a comparative analysis with well-differentiated squamous carcinoma. Int J Gynecol Pathol 10:59–66
Wong WW, Hirose T, Scheithauer BW et al (1998) Malignant peripheral nerve sheath tumor: analysis of treatment outcome. Int J Radiat Oncol Biol Phys 42:351–360
Woodruff JM, Marshall ML, Godwin TA et al (1983) Plexiform (multinodular) schwannoma. A tumor simulating the plexiform neurofibroma. Am J Surg Pathol 7:691–697
Wrotnowski U, Cooper PH, Shmookler BM (1988) Fibrosarcomatous change in dermatofibrosarcoma protuberans. Am J Surg Pathol 12:287–293
Xiao P, Peng J-J, Li Y et al (2013) Unusual calcifying fibrous tumor in the fallopian tube: review and discussion of the differential diagnosis. Int J Gynecol Pathol 33:40–44
Yamashita Y, Yamada T, Ueki K et al (1996) A case of vulvar schwannoma. J Obstet Gynaecol Res 22:31–34
Yamawaki T, Hirai Y, Takeshima N et al (1996) Ovarian hemangioma associated with concomitant stromal luteinization and ascites. Gynecol Oncol 61:438–441
Yang W, Li G, Wei-qiang Z (2012) Multifocal PEComa (PEComatosis) of the female genital tract and pelvis: a case report and review of the literature. Diagn Pathol 7:23
Yoshida A, Tsuta K, Ohno M et al (2014) STAT6 immunohistochemistry is helpful in the diagnosis of solitary fibrous tumors. Am J Surg Pathol 38:552–559
Yoshida A, Yoshida H, Yoshida M et al (2015) Myoepithelioma-like tumors of the vulvar region. A distinctive group of SMARCB1-deficient neoplasms. Am J Surg Pathol 39:1102–1113
Yousem HL, Dorfman HD (1962) Myometrial involvement in von Recklinghausen’s disease: report of a case. Obstet Gynecol 20:781–784
Zreik RT, Fritchie KJ (2016) Morphologic spectrum of desmoid-type fibromatosis. Am J Clin Pathol 145:332–340
Zubor P, Kajo K, Szunyogh N et al (2007) A solitary fibrous tumor in the broad ligament of the uterus. Pathol Res Pract 203:555–560
Zudaire T, Guarch R, Valcayo A et al (2017) Primary Langerhans cell histiocytosis of the vulva: case report and review of the literature. Int J Gynecol Pathol 36:111–114
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Fetsch, J.F., Laskin, W.B. (2019). Soft Tissue Lesions Involving Female Reproductive Organs. In: Kurman, R., Hedrick Ellenson, L., Ronnett, B. (eds) Blaustein's Pathology of the Female Genital Tract. Springer, Cham. https://doi.org/10.1007/978-3-319-46334-6_22
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