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Treatment of Acute Respiratory Distress Syndrome in the Poisoned Patient

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Critical Care Toxicology

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Abstract

Lung-damaging toxicants may be defined as chemicals that induce pathological changes in the lung following absorption [1, 2]. The acute respiratory distress syndrome (ARDS) is a clinical syndrome which might be caused by direct damage to the respiratory cells at the alveolar level or indirectly through inflammation mediators in a severely exposed patient.

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Acknowledgments

Parts of this chapter are based upon chapters written by Dorsett D. Smith and Jeffrey L. Burgess in previous editions of this book.

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Authors and Affiliations

  1. Department of Intensive Care Medicine and the Dutch National Poison Information Center, (NPIC) of the University Medical Center, University Utrecht, Heidelberglaan 100, 85500, 3584 CX, Utrecht, The Netherlands

    Dylan W. de Lange

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  1. Dylan W. de Lange
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Correspondence to Dylan W. de Lange .

Editor information

Editors and Affiliations

  1. Department of Medicine, Division of Clinical Pharmacology and Toxicology, University of Colorado, School of Medicine, Aurora, Colorado, USA

    Jeffrey Brent

  2. FDA, Office of New Drugs/Immediate Office, Center for Drug Evaluation and Research, Silver Spring, Maryland, USA

    Keith Burkhart

  3. Clinical Toxicology, St Thomas’ Hospital, Silver Spring, Maryland, USA

    Paul Dargan

  4. Toxicology Associates, University of Colorado, School of Medicine, Denver, Colorado, USA

    Benjamin Hatten

  5. Medical Toxicological Intensive Care Unit, Lariboisiere Hospital, Paris-Diderot University, Paris, France

    Bruno Megarbane

  6. Toxicology Associates, University of Colorado, School of Medicine, Denver, Colorado, USA

    Robert Palmer

  7. Toxinology Department, Women’s and Children’s Hospital, North Adelaide, South Australia, Australia

    Julian White

Grading System for Levels of Evidence Supporting Recommendations in Critical Care Toxicology, 2nd Edition

  1. I

    Evidence obtained from at least one properly randomized controlled trial.

  2. II-1

    Evidence obtained from well-designed controlled trials without randomization.

  3. II-2

    Evidence obtained from well-designed cohort or case–control analytic studies, preferably from more than one center or research group.

  4. II-3

    Evidence obtained from multiple time series with or without the intervention. Dramatic results in uncontrolled experiments (such as the results of the introduction of penicillin treatment in the 1940s) could also be regarded as this type of evidence.

  5. III

    Opinions of respected authorities, based on clinical experience, descriptive studies and case reports, or reports of expert committees.

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© 2017 Springer International Publishing AG

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de Lange, D.W. (2017). Treatment of Acute Respiratory Distress Syndrome in the Poisoned Patient. In: Brent, J., et al. Critical Care Toxicology. Springer, Cham. https://doi.org/10.1007/978-3-319-17900-1_66

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