1. Measuring Blood Pressure in Clinical Practice: We Can and Must Do Better

   • J. Rick Turner

   Editorial 30 December 2018 Pages: 685 - 686

2. European Pharma Oligonucleotide Consortium A Move to Consolidate Oligonucleotide Knowledge and Share Experience Within the Community

   • Anna Tivesten
   • Nadim Akhtar
   • Thomas Eichinger

   Letter to the Editor 30 December 2018 Pages: 687 - 688

3. Value of IRB in Expanded Access

   • Richard Klein
   • Marjorie A. Speers

   Letter to the Editor 30 December 2018 Pages: 689 - 689

4. Clinical Study Design to Assess Both Short- and Long-term Efficacy in Addition to Group Sequential Test on Safety

   • Jiacheng Yuan
   • Peter Mesenbrink
   • Gary Koch

   Biostatistics: Original Article 30 December 2018 Pages: 690 - 695

5. The Safety Explorer Suite: Interactive Safety Monitoring for Clinical Trials

   • Jeremy Wildfire
   • Ryan Bailey
   • Jack G. Modell

   Clinical Trials: Original Article 30 December 2018 Pages: 696 - 700

6. CRISPR-Cas9: A Precise Approach to Genome Engineering

   • Jorge E. Simón
   • Ángel S. Rodríguez
   • Nelson Santiago Vispo

   Clinical Trials: Review 30 December 2018 Pages: 701 - 707

7. Advancing the Practice of CRCs Why Professional Development Matters

   • Linda S. Behar-Horenstein
   • Alena Prikhidko
   • H. Robert Kolb

   Educational Perspectives: Original Article 30 December 2018 Pages: 708 - 717

8. Anticancer Drug Prescription Patterns in Japan: Future Directions in Cancer Therapy

   • Shoyo Shibata
   • Maiko Matsushita
   • Takeshi Suzuki

   Global Perspectives: Original Article 30 December 2018 Pages: 718 - 723

9. What Drives Adoption of National Labels as Global Reference Labels? A Case Study With the JPI

   • Shimon Yoshida
   • Rie Matsui
   • Chikara Kikuchi

   Global Perspectives: Original Article 30 December 2018 Pages: 724 - 730

10. Relationship Between the Review Time and Various PMDA Consultations in Recent New Drug Approval Cases in Japan

    • Keiji Nishiyama
    • Satoshi Toyoshima
    • Naomi Nagai

    Global Perspectives: Original Article 30 December 2018 Pages: 731 - 738

11. Recent Advances in Drug Development and Regulatory Science in China

    • Jie Chen
    • Naiqing Zhao

    Global Perspectives: Original Article 30 December 2018 Pages: 739 - 750

12. Strengthening Health Products Regulatory Systems to Enhance Access to Quality Health Products in the Asia-Pacific

    • John C. W. Lim

    Global Perspectives: Commentary 30 December 2018 Pages: 751 - 754

13. Incremental Cost-Effectiveness Ratio and Net Monetary Benefit: Promoting the Application of Value-Based Pricing to Medical Devices—A European Perspective

    • Andrea Messori
    • Sabrina Trippoli

    Global Perspectives: Letter to the Editor 30 December 2018 Pages: 755 - 756

14. Patient Reporting of Adverse Drug Reactions (ADRs): Survey of Public Awareness and Predictors of Confidence to Report

    • Vidhya Hariraj
    • Zoriah Aziz

    Product Safety: Original Article 30 December 2018 Pages: 757 - 763

15. Survey of Safety Information in the Investigator’s Brochure: Inconsistencies and Recommendations

    • Michael Jacob Klepper
    • Leander Fontaine

    Product Safety: Original Article 30 December 2018 Pages: 764 - 770

16. Outdated Prescription Drug Labeling: How FDA-Approved Prescribing Information Lags Behind Real-World Clinical Practice

    • Michael B. Shea
    • Mark Stewart
    • Ellen Sigal

    Regulatory Science: Original Article 30 December 2018 Pages: 771 - 777

17. The Use of Real-World Evidence and Data in Clinical Research and Postapproval Safety Studies

    • Mary Jo Lamberti
    • Wayne Kubick
    • Ken Getz

    Regulatory Science: Original Article 30 December 2018 Pages: 778 - 783

18. Product Approvability Recommendations From FDA Advisory Committees: Inconsistently Sought, Indirectly Obtained

    • Joseph V. Gulfo
    • Jason Briggeman
    • Asmaa Gamie

    Regulatory Science: Original Article 30 December 2018 Pages: 784 - 792

19. Regional Approaches to Expedited Drug Development and Review: Can Regulatory Harmonization Improve Outcomes?

    • Elizabeth Richardson
    • Gregory Daniel
    • Jonathan P. Jarow

    Regulatory Science: Meeting Report 30 December 2018 Pages: 793 - 798