Use of the folinic acid/5-fluorouracil/irinotecan (FOLFIRI 1) regimen in elderly patients as a first-line treatment for metastatic colorectal cancer: a Phase II study Eric FrançoisJean-François BerdahVéronique Mari Original Article 14 February 2008 Pages: 931 - 936
Dynamics of antifolate transport via the reduced folate carrier and the membrane folate receptor in murine leukaemia cells in vitro and in vivo Robert MauritzGodefridus J. PetersGerrit Jansen Original Article Open access 19 February 2008 Pages: 937 - 948
Inhibition of CD44 expression in hepatocellular carcinoma cells enhances apoptosis, chemosensitivity, and reduces tumorigenesis and invasion Zhigang XiePei Feng ChoongChien-Shing Chen Original Article 08 February 2008 Pages: 949 - 957
Th1/Th2 balance: an important indicator of efficacy for intra-arterial chemotherapy Hidenari NagaiDaisuke MiyakiKazumasa Miki Original Article 08 February 2008 Pages: 959 - 963
BRCA1 transcriptional activity is enhanced by interactions between its AD1 domain and AhR Hyo Jin KangHee Jeong KimInsoo Bae Original Article 08 February 2008 Pages: 965 - 975
Disruption of microfilaments by cytochalasin B decreases accumulation of cisplatin in human epidermal carcinoma and liver carcinoma cell lines Xing-Jie LiangJun-Jie YinAdorjan Aszalos Original Article 15 February 2008 Pages: 977 - 984
Non-invasive MRI tumor imaging and synergistic anticancer effect of HSP90 inhibitor and glycolysis inhibitor in RIP1-Tag2 transgenic pancreatic tumor model Xianhua CaoGuang JiaDuxin Sun Original Article 06 February 2008 Pages: 985 - 994
Interleukin-6 protects against paclitaxel, cisplatin and vincristine-induced neuropathies without impairing chemotherapeutic activity Noelle CallizotEmile AndriambelosonMichel Dreano Original Article 13 February 2008 Pages: 995 - 1007
Salvage treatment with topotecan in patients with irinotecan-refractory small cell lung cancer Se Hoon ParkEun Kyung ChoJae Hoon Lee Original Article 08 February 2008 Pages: 1009 - 1014
Reversal of P-glycoprotein-mediated multidrug resistance of cancer cells by five schizandrins isolated from the Chinese herb Fructus Schizandrae Min HuangJing JinGeng Tao Liu Original Article 13 February 2008 Pages: 1015 - 1026
Pharmacokinetics of irinotecan and its metabolites in pediatric cancer patients: a report from the children’s oncology group Patrick A. ThompsonManish GuptaJohn Mondick Original Article 16 February 2008 Pages: 1027 - 1037
Topotecan distribution in an anephric infant with therapy resistant bilateral Wilms tumor with a novel germline WT1 gene mutation Rieneke T. LugtenbergKarlien CransbergMarry M. van den Heuvel-Eibrink Original Article Open access 14 February 2008 Pages: 1039 - 1044
Pharmacokinetic profile of the microtubule stabilizer patupilone in tumor-bearing rodents and comparison of anti-cancer activity with other MTS in vitro and in vivo Terence O’ReillyMarkus WartmannPaul M. J. McSheehy Original Article 27 February 2008 Pages: 1045 - 1054
Inducing apoptosis and enhancing chemosensitivity to Gemcitabine via RNA interference targeting Mcl-1 gene in pancreatic carcinoma cell San-Hua WeiKe DongHui-Zhong Zhang Original Article 23 February 2008 Pages: 1055 - 1064
Identification and validation of phospho-SRC, a novel and potential pharmacodynamic biomarker for dasatinib (SPRYCEL™), a multi-targeted kinase inhibitor Feng (Roger) LuoYu Chen BarrettFrancis Y. Lee Original Article Open access 27 February 2008 Pages: 1065 - 1074
Cisplatin plus weekly CPT-11/docetaxel in advanced esophagogastric cancer: a phase I study with pharmacogenetic assessment of XPD, XRCC3 and UGT1A1 polymorphisms Albert FontRamon SalazarRafael Rosell Original Article 12 March 2008 Pages: 1075 - 1083
Phase-II study of weekly schedule of trastuzumab, paclitaxel, and carboplatin followed by a week off every 28 days for HER2+ metastatic breast cancer M. RuizJ. SalvadorA. Lopez-Ladrón Original Article 26 March 2008 Pages: 1085 - 1090
Toxicity and toxicokinetics of the cyclin-dependent kinase inhibitor AG-024322 in cynomolgus monkeys following intravenous infusion Alan P. BrownCynthia L. CourtneyBart A. Jessen Original Article 29 May 2008 Pages: 1091 - 1101
A multicenter phase II study of biweekly paclitaxel and S-1 combination chemotherapy for unresectable or recurrent gastric cancer Akihiro NakajoShuichi HokitaKyushu Taxol, TS-1, Study Group (KTT-SG) Clinical Trial Report 04 March 2008 Pages: 1103 - 1109
Tumor resensitization to erlotinib following brief substitution of cetuximab R. J. EpsteinT. W. Leung Short Communication 19 February 2008 Pages: 1111 - 1112
Is oncogenesis a normal cellular defense mechanism? Steven SorscherAubrey E. HillEric J. Sorscher Letter to the editor 15 February 2008 Pages: 1113 - 1113
Professor Lloyd R. Kelland: man of science Herbie NewellMark McKeageClive Stanway Obituary 27 August 2008 Pages: 1115 - 1116
