1. Editorial

   • Klaus A. Miczek

   EditorialNotes Pages: 1 - 1

2. A comparison of trazodone and fluoxetine: implications for a serotonergic mechanis of antidepressant action

   • Gerard J. Marek
   • Christopher J. McDougle
   • Lewis S. Seiden

   Reviews Pages: 2 - 11

3. Psychopharmacological properties of calcium channel inhibitors

   • Olgierd Pucilowski

   Reviews Pages: 12 - 29

4. Dose-response studies with co-dergocrine mesylate under hypoxia utilizing EEG mapping and psychometry

   • Bernd Saletu
   • Josef Grünberger
   • Peter Anderer

   Original Investigations Pages: 30 - 40

5. Parametric and pharmacological analyses of the enhanced grooming response elicited by the D1 dopamine receptor agonist SKF 38393 in the rat

   • Stephen R. Wachtel
   • Richard J. Brooderson
   • Francis J. White

   Original Investigations Pages: 41 - 48

6. Motor activity following the administration of selective D-1 and D-2 dopaminergic drugs to MPTP-treated common marmosets

   • Peter-A. Löschmann
   • Lance A. Smith
   • C. David Marsden

   Original Investigations Pages: 49 - 56

7. Imipramine and 2-hydroxyimipramine: comparative cardiotoxicity and pharmacokinetics in swine

   • Bruce G. Pollock
   • James M. Perel

   Original Investigations Pages: 57 - 62

8. Tolerance, withdrawal, and supersensitivity to dopamine mediated cues in a drug-drug discrimination

   • Robert J. Barrett
   • David K. White
   • William F. Caul

   Original Investigations Pages: 63 - 67

9. Specific effects of the benzodiazepine midazolam on visual receptive fields in light and dark adapted human subjects

   • M. Groner
   • H. -U. Fisch
   • B. Bircher

   Original Investigations Pages: 68 - 76

10. Activation of 5-HT_1C-receptors suppresses excessive wheel running induced by semi-starvation in the rat

    • T. Wilckens
    • U. Schweiger
    • K. M. Pirke

    Original Investigations Pages: 77 - 84

11. Forced-choice versus free-choice procedures: Caffeine self-administration in humans

    • Alison H. Oliveto
    • John R. Hughes
    • James W. Fenwick

    Original Investigations Pages: 85 - 91

12. Oral ethanol self-administration in rats is reduced by the administration of dopamine and glutamate receptor antagonists into the nucleus accumbens

    • Stefanie Rassnick
    • Luigi Pulvirenti
    • George F. Koob

    Original Investigations Pages: 92 - 98

13. Drug discrimination studies in rats with caffeine and phenylpropanolamine administered separately and as mixtures

    • E. A. Mariathasan
    • I. P. Stolerman

    Original Investigations Pages: 99 - 106

14. Differential development of acute tolerance to the motor impairment and anticonvulsant effects of ethanol

    • A. D. Lê
    • M. Mana
    • H. Kalant

    Original Investigations Pages: 107 - 111

15. Tolerance to ethanol's effects on operant performance in rats: role of number and pattern of intoxicated practice opportunities

    • Frank A. Holloway
    • Ron C. Michaelis
    • David V. Gauvin

    Original Investigations Pages: 112 - 120

16. Effects of caffeine, time of day and user history on study-related performance

    • Paula J. Mitchell
    • Jennifer R. Redman

    Original Investigations Pages: 121 - 126

17. Comparative effects of alpha-2 receptor agents and THA on the performance of adult and aged rats in the delayed non-matching to position task

    • Jouni Sirviö
    • Maija Harju
    • Paavo J. Riekkinen

    Original Investigations Pages: 127 - 133

18. Effects of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) after repeated administration on a conditioned avoidance response (CAR) in the rat

    • J. L. Evenden

    Original Investigations Pages: 134 - 144

19. Effects of methylphenidate on response rate and measures of motor performance and reinforcement efficacy

    • Gene M. Heyman

    Original Investigations Pages: 145 - 152

20. Effect of acute and chronic benzodiazepines on plasma GABA in anxious patients and controls

    • Peter P. Roy-Byrne
    • Deborah S. Cowley
    • Frederick Petty

    Original Investigations Pages: 153 - 156

21. Roles ofδ andμ opioid receptors in mediating the effects of enkephalins on avoidance conditioning

    • Gery Schulteis
    • Joe L. Martinez Jr

    Original Investigations Pages: 157 - 162

22. Interactions of theβ carboline abecarnil with the high pressure neurological syndrome in a primate model

    • P. C. Pearce
    • M. J. Halsey
    • E. M. Ward

    Original Investigations Pages: 163 - 171

23. Effect of number of conditioning trials on the development of associative tolerance to morphine

    • Antonio Cepeda-Benito
    • Stephen T. Tiffany

    Original Investigations Pages: 172 - 176

24. Corticotropin-releasing factor modulates dietary preference in nutritionally and physically stressed rats

    • Stephen C. Heinrichs
    • George F. Koob

    Original Investigations Pages: 177 - 184

25. Contribution of associative and nonassociative processes to the development of morphine tolerance

    • Stephen T. Tiffany
    • David J. Drobes
    • Antonio Cepeda-Benito

    Original Investigations Pages: 185 - 190

26. Neonatal administration of a GABA-T inhibitor alters central GABA_A receptor mechanisms and alcohol drinking in adult rats

    • T. Taira
    • T. Porkka-Heiskanen
    • E. R. Korpi

    Original Investigations Pages: 191 - 197

27. Effects of physostigmine on stimulus encoding in a memory-scanning task

    • Anthony Wetherell

    Original Investigations Pages: 198 - 202

28. Dissociation between the effects of benzodiazepine receptor agonists on behavioral vigilance and responsivity

    • Paul Dudchenko
    • Brooke Paul
    • Martin Sarter

    Original Investigations Pages: 203 - 211

29. Effect of 5-HT agonists on rats fed single diets with varying proportions of carbohydrate and protein

    • Shuqin Luo
    • Edmund T. S. Li

    Original Investigations Pages: 212 - 216

30. Context-drug pairings enhance tolerance to ethanol-induced disruption of operant responding

    • Christopher L. Cunningham
    • Steven M. Losli
    • Fred O. Risinger

    Original Investigations Pages: 217 - 222

31. Attenuation of muscarinic receptor blockade-induced impairment of spatial delayed alternation performance by the triazole MDL 26,479

    • L. A. Holley
    • P. Dudchenko
    • M. Sarter

    Original Investigations Pages: 223 - 230

32. Platelet adenylate cyclase activity in depression and after clomipramine and lithium treatment: relation to serotonergic function

    • Michael E. Newman
    • Bernard Lerer
    • Baruch Shapira

    Original Investigations Pages: 231 - 234

33. Clonidine but not nifedipine prevents the release of noradrenaline during naloxone-precipitated opiate withdrawal: an in vivo microdialysis study in the rat

    • Peter H. Silverstone
    • Christopher Done
    • Trevor Sharp

    Original Investigations Pages: 235 - 238

34. Role of central ATP-sensitive potassium channels in the hyperthermic effect of morphine in mice

    • Minoru Narita
    • Tsutomu Suzuki
    • Hiroshi Nagase

    Rapid Communications Pages: 239 - 240

35. Selective effects of the D₁ dopamine receptor agonist, SKF 38393, on behavior maintained by cocaine injection in squirrel monkeys

    • Jonathan L. Katz
    • Jeffrey M. Witkin

    Rapid Communications Pages: 241 - 244

36. Cocaine decreases self-control in rats: a preliminary report

    • A. W. Logue
    • Henry Tobin
    • Stanley Schachter

    Rapid Communications Pages: 245 - 247

37. Effects of chronic nicotine and haloperidol administration on muscarinic receptor-mediated phosphoinositide turnover in rat brain slices

    • Rena Li
    • Lauren L. Wing
    • De-Maw Chuang

    Rapid Communications Pages: 248 - 250

38. Evidence that the large neutral amino acidl-valine decreases electrically-evoked release of 5-HT in rat hippocampus in vivo

    • S. E. Gartside
    • P. J. Cowen
    • T. Sharp

    Rapid Communications Pages: 251 - 253

39. Effects of zolpidem and flunitrazepam on nocturnal sleep of women subjectively complaining of insomnia

    • A. C. Declerck
    • F. Ruwe
    • A. Wauquier

    Erratum Pages: 254 - 254