In memoriam Thomas Gebel Jan G. HengstlerHermann BoltRobert Landsiedel Memoriam Open access 14 March 2023 Pages: 1193 - 1194
A review of cardiovascular effects and underlying mechanisms of legacy and emerging per- and polyfluoroalkyl substances (PFAS) Zeng-Jin WenYi-Jing WeiYin-Feng Zhang Review Article 22 March 2023 Pages: 1195 - 1245
Toxicology of 3-monochloropropane-1,2-diol and its esters: a narrative review Elena FattoreAlessia LannoEnrico Davoli Review Article 24 February 2023 Pages: 1247 - 1265
Modernizing persistence–bioaccumulation–toxicity (PBT) assessment with high throughput animal-free methods Beate I. EscherRolf AltenburgerKathrin Fenner Regulatory Toxicology Open access 23 March 2023 Pages: 1267 - 1283
A mixture of 13 pesticides, contaminants, and food additives below individual NOAELs produces histopathological and organ weight changes in rats Viorica DincaAnca Oana DoceaAristidis Tsatsakis Regulatory Toxicology Open access 09 March 2023 Pages: 1285 - 1298
The role of hypoxia-inducible factor 1 alpha (HIF-1α) modulation in heavy metal toxicity Michael AschnerAnatoly V. SkalnyAlexey A. Tinkov Inorganic Compounds 18 March 2023 Pages: 1299 - 1318
PBTK modeling of the pyrrolizidine alkaloid retrorsine to predict liver toxicity in mouse and rat Anja LehmannIna GeburekChristoph Hethey Toxicokinetics and Metabolism Open access 11 March 2023 Pages: 1319 - 1333
Metabolic signature of HepaRG cells exposed to ethanol and tumor necrosis factor alpha to study alcoholic steatohepatitis by LC–MS-based untargeted metabolomics Elias IturrospeRani RobeynsAdrian Covaci oxicogenomics and Omics Technologies 24 February 2023 Pages: 1335 - 1353
Hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) causes seizure activity in larval zebrafish via antagonism of γ-aminobutyric acid type A receptor α1β2γ2 Paige C. MundyAlicia WernerPamela J. Lein Molecular Toxicology Open access 13 March 2023 Pages: 1355 - 1365
Off-target activity of NBOMes and NBOMe analogs at the µ opioid receptor Marie H. DeventerMattias PerssonChristophe P. Stove Molecular Toxicology 28 February 2023 Pages: 1367 - 1384
Lysosomal dysfunction in Schwann cells is involved in bortezomib-induced peripheral neurotoxicity Zhanxun WuWenping YanJiaying Wu Organ Toxicity and Mechanisms 24 February 2023 Pages: 1385 - 1396
Dose-dependent pleiotropic role of neutrophils during acetaminophen-induced liver injury in male and female mice Nga T. NguyenDavid S. UmbaughHartmut Jaeschke Organ Toxicity and Mechanisms 16 March 2023 Pages: 1397 - 1412
Potency ranking of pyrrolizidine alkaloids in metabolically competent human liver cancer cells and primary human hepatocytes using a genotoxicity test battery Manuel HaasKarina WirachowskiJörg Fahrer Genotoxicity and Carcinogenicity Open access 16 March 2023 Pages: 1413 - 1428
Organoid-based 3D in vitro microphysiological systems as alternatives to animal experimentation for preclinical and clinical research Chrianjay MukhopadhyayManash K. Paul Letter to the Editor, News and Views 14 March 2023 Pages: 1429 - 1431
ECHA ARN documents: chemical grouping without a toxicological rationale Andreas NatschGreg AdamssonVanessa Rocha Letter to the Editor, News and Views Open access 22 March 2023 Pages: 1433 - 1437