Pharmacology and toxicology of eteplirsen and SRP-5051 for DMD exon 51 skipping: an update Omar SheikhToshifumi Yokota Review Article 19 November 2021 Pages: 1 - 9
Four decades of chemotherapy-induced cognitive dysfunction: comprehensive review of clinical, animal and in vitro studies, and insights of key initiating events Ana Dias-CarvalhoMariana FerreiraVera Marisa Costa Review Article 02 November 2021 Pages: 11 - 78
Quo vadis blood protein adductomics? Gabriele SabbioniBilly W. Day Review Article Open access 13 November 2021 Pages: 79 - 103
Case study: risk associated to wearing silver or graphene nanoparticle-coated facemasks for protection against COVID-19 Carmen EstevanEugenio VilanovaMiguel A. Sogorb Nanotoxicology Open access 16 November 2021 Pages: 105 - 119
Human metabolism and urinary excretion of seven neonicotinoids and neonicotinoid-like compounds after controlled oral dosages Sonja A. WrobelDaniel BuryHeiko U. Käfferlein Toxicokinetics and Metabolism Open access 13 October 2021 Pages: 121 - 134
Physiologically based kinetic modelling predicts the in vivo relative potency of riddelliine N-oxide compared to riddelliine in rat to be dose dependent Frances WidjajaSebastiaan WesselingIvonne M. C. M. Rietjens Toxicokinetics and Metabolism Open access 20 October 2021 Pages: 135 - 151
Investigations on detoxification mechanisms of novel para-phenylenediamine analogues through N-acetyltransferase 1 (NAT-1) Gopalakrishnan VenkatesanZhi Chiaw LimGiorgia Pastorin Toxicokinetics and Metabolism 12 November 2021 Pages: 153 - 165
Estimating the reduction in US mortality if cigarettes were largely replaced by e-cigarettes Peter N. LeeJohn S. FryAndrew R. Joyce Bioinformatics and Statistics Open access 22 October 2021 Pages: 167 - 176
Inhibitors of class I HDACs and of FLT3 combine synergistically against leukemia cells with mutant FLT3 Vanessa WachholzAl-Hassan M. MustafaOliver H. Krämer Molecular Toxicology Open access 19 October 2021 Pages: 177 - 193
Expression dynamics of pregnane X receptor-controlled genes in 3D primary human hepatocyte spheroids Tomas SmutnyVeronika BernhauerovaPetr Pavek Molecular Toxicology 23 October 2021 Pages: 195 - 210
Investigating the in vitro steatotic mixture effects of similarly and dissimilarly acting test compounds using an adverse outcome pathway-based approach Jimmy AlarcanGeorges de SousaDajana Lichtenstein Molecular Toxicology Open access 15 November 2021 Pages: 211 - 229
Deoxynivalenol induces apoptosis and autophagy in human prostate epithelial cells via PI3K/Akt signaling pathway Karolina KowalskaMarta Justyna KoziełAgnieszka Wanda Piastowska-Ciesielska Molecular Toxicology Open access 22 October 2021 Pages: 231 - 241
DMSO-free highly differentiated HepaRG spheroids for chronic toxicity, liver functions and genotoxicity studies Sophie RoseMarie CuvellierSophie Langouët In vitro systems 11 November 2021 Pages: 243 - 258
Mapping the cellular response to electron transport chain inhibitors reveals selective signaling networks triggered by mitochondrial perturbation Wanda van der StelHuan YangErik H. J. Danen In vitro systems Open access 13 October 2021 Pages: 259 - 285
Particulate and drug-induced toxicity assessed in novel quadruple cell human primary hepatic disease models of steatosis and pre-fibrotic NASH Ali KermanizadehJessica ValliVicki Stone In vitro systems Open access 20 October 2021 Pages: 287 - 303
Kupffer cells regulate liver recovery through induction of chemokine receptor CXCR2 on hepatocytes after acetaminophen overdose in mice Nga T. NguyenDavid S. UmbaughHartmut Jaeschke Organ Toxicity and Mechanisms 01 November 2021 Pages: 305 - 320
Organophosphorus pesticides exhibit compound specific effects in rat precision-cut lung slices (PCLS): mechanisms involved in airway response, cytotoxicity, inflammatory activation and antioxidative defense Jonas TiggesFranz WorekTimo Wille Organ Toxicity and Mechanisms Open access 15 November 2021 Pages: 321 - 334
Persistent autism-relevant behavioral phenotype and social neuropeptide alterations in female mice offspring induced by maternal transfer of PBDE congeners in the commercial mixture DE-71 Elena V. KozlovaMatthew C. ValdezMargarita C. Curras-Collazo Developmental Toxicology Open access 23 October 2021 Pages: 335 - 365
Functional variants of RPS6KB1 and PIK3R1 in the autophagy pathway genes and risk of bladder cancer Lan MaDongjian ZhangZhengdong Zhang Genotoxicity and Carcinogenicity 19 October 2021 Pages: 367 - 375
Single-strand specific nuclease enhances accuracy of error-corrected sequencing and improves rare mutation-detection sensitivity Yuki OtsuboShoji MatsumuraMasayuki Yamane Genotoxicity and Carcinogenicity Open access 12 November 2021 Pages: 377 - 386