Chronic brain damage in HIV-infected individuals under antiretroviral therapy is associated with viral reservoirs, sulfatide release, and compromised cell-to-cell communication Daniela D’AmicoRosario BaroneEliseo A. Eugenin Original Article 04 April 2023 Article: 116
circPTPN14 promotes renal fibrosis through its interaction with FUBP1 to enhance MYC transcription Jian-Kang ZhouJiao LiYong Peng Commentary 04 April 2023 Article: 115
Inhibiting a promiscuous GPCR: iterative discovery of bitter taste receptor ligands Fabrizio FierroLior PeriMasha Y Niv Original Article 03 April 2023 Article: 114
Receptor clustering by a precise set of extracellular galectins initiates FGFR signaling Dominika ZukowskaAleksandra GedajLukasz Opalinski Original Article Open access 03 April 2023 Article: 113
USP35 dimer prevents its degradation by E3 ligase CHIP through auto-deubiquitinating activity Jinyoung ParkSang Chul ShinEun Joo Song Original Article 01 April 2023 Article: 112
SEMA6C: a novel adhesion-independent FAK and YAP activator, required for cancer cell viability and growth Damon FardErika TestaLuca Tamagnone Original Article Open access 31 March 2023 Article: 111
Functional effects of disease-associated variants reveal that the S1–M1 linker of the NMDA receptor critically controls channel opening Lingling XieMiranda J. McDanielStephen F. Traynelis Original Article 31 March 2023 Article: 110
A zebrafish model of growth hormone insensitivity syndrome with immune dysregulation 1 (GHISID1) Somayyeh HeidaryNagendra AwasthiAlister C. Ward Original Article Open access 30 March 2023 Article: 109
Chronic stress targets mitochondrial respiratory efficiency in the skeletal muscle of C57BL/6 mice Aleksandra NikolicPia FahlbuschBirgit Knebel Original Article Open access 29 March 2023 Article: 108
The RNA-binding protein FUS/TLS interacts with SPO11 and PRDM9 and localize at meiotic recombination hotspots Teresa GiannattasioErika TestaMarco Barchi Original Article Open access 26 March 2023 Article: 107
Podocyte-specific deletion of ubiquitin carboxyl-terminal hydrolase L1 causes podocyte injury by inducing endoplasmic reticulum stress Yuan HuChenyang QiZhigang Zhang Original Article 23 March 2023 Article: 106
Restriction of access to the central cavity is a major contributor to substrate selectivity in plant ABCG transporters Konrad PakułaCarlos Sequeiros-BorjaMichał Jasiński Original Article Open access 23 March 2023 Article: 105
Receptor tyrosine kinase inhibitors in cancer Nasim EbrahimiElmira FardiAmir Reza Aref Review 22 March 2023 Article: 104
Integrative epigenetic analysis reveals AP-1 promotes activation of tumor-infiltrating regulatory T cells in HCC Baowen ZhuoQifan ZhangBo Guo Original Article 20 March 2023 Article: 103
The forkhead box O3 (FOXO3): a key player in the regulation of ischemia and reperfusion injury Moussa OmorouYiwei HuangHui Xu Review 20 March 2023 Article: 102
Pharmacological and mechanistic study of PS1, a Pdia4 inhibitor, in β-cell pathogenesis and diabetes in db/db mice Hui-Ju TsengWen-Chu ChenWei-Jan Huang Original Article Open access 19 March 2023 Article: 101
Loss of Kmt2c in vivo leads to EMT, mitochondrial dysfunction and improved response to lapatinib in breast cancer Nikiana SimigdalaAnna ChalariApostolos Klinakis Original Article Open access 18 March 2023 Article: 100
lncRNA miR4458HG modulates hepatocellular carcinoma progression by activating m6A-dependent glycolysis and promoting the polarization of tumor-associated macrophages Ying YeMenghan WangWei Xia Original Article 18 March 2023 Article: 99
Endogenous but not sensory-driven activity controls migration, morphogenesis and survival of adult-born juxtaglomerular neurons in the mouse olfactory bulb Kaizhen LiKatherine FigarellaOlga Garaschuk Original Article Open access 18 March 2023 Article: 98
The η-secretase-derived APP fragment ηCTF is localized in Golgi, endosomes and extracellular vesicles and contributes to Aβ production Elissa AframInger LauritzenFrederic Checler Original Article Open access 17 March 2023 Article: 97
Inhibition of LXR controls the polarization of human inflammatory macrophages through upregulation of MAFB Arturo González de la AlejaCristina HerreroÁngel L. Corbí Original Article Open access 17 March 2023 Article: 96
Aggregation-prone TDP-43 sequesters and drives pathological transitions of free nuclear TDP-43 Sean S. KeatingAdekunle T. BademosiAdam K. Walker Original Article Open access 17 March 2023 Article: 95
Correction: CHIP induces ubiquitination and degradation of HMGB1 to regulate glycolysis in ovarian endometriosis Yujun SunQian WangTingting Yang Correction 17 March 2023 Article: 94
Microstructured soft devices for the growth and analysis of populations of homogenous multicellular tumor spheroids Ottavia TartagniAlexandra BorókGiampaolo Zuccheri Original Article Open access 16 March 2023 Article: 93
UBE2T resolves transcription-replication conflicts and protects common fragile sites in primordial germ cells Yongze YuWeiwei XuShidou Zhao Original Article 16 March 2023 Article: 92
KIF13B mediates VEGFR2 recycling to modulate vascular permeability Hyun-Dong ChoNguyễn Thị Thanh NhànKaori H. Yamada Original Article 16 March 2023 Article: 91
Extracellular vesicles from hyperammonemic rats induce neuroinflammation in hippocampus and impair cognition in control rats Paula Izquierdo-AltarejosMar Martínez-GarcíaVicente Felipo Original Article 15 March 2023 Article: 90
Mesenchyme-derived vertebrate lonesome kinase controls lung organogenesis by altering the matrisome Salome M. BrütschElizabeta MadzharovaMattia R. Bordoli Original Article Open access 15 March 2023 Article: 89
Brain washing and neural health: role of age, sleep, and the cerebrospinal fluid melatonin rhythm Russel J. ReiterRamaswamy SharmaLuiz Gustavo de Almeida Chuffa Review 14 March 2023 Article: 88
A Rab10–ACAP1–Arf6 GTPases cascade modulates M4 muscarinic acetylcholine receptor trafficking and signaling Rongmei XuMin WanRongying Zhang Original Article 14 March 2023 Article: 87
AAV-Net1 facilitates the trans-differentiation of supporting cells into hair cells in the murine cochlea Liyan ZhangYuan FangRenjie Chai Original Article 14 March 2023 Article: 86
Correction: An oncogene addiction phosphorylation signature and its derived scores inform tumor responsiveness to targeted therapies Eleonora OrlandoMatúš MedoYitzhak Zimmer Correction Open access 10 March 2023 Article: 85
The TIMELESS effort for timely DNA replication and protection Jinal A. PatelHyungjin Kim Review Open access 09 March 2023 Article: 84
On the assembly of the mitotic spindle, bistability and hysteresis Angela Flavia SerpicoCaterina PisauroDomenico Grieco Visions and reflections Open access 08 March 2023 Article: 83
Mice deficient in synaptic protease neurotrypsin show impaired spaced long-term potentiation and blunted learning-induced modulation of dendritic spines Maura Ferrer-FerrerShaobo JiaAlexander Dityatev Original Article Open access 05 March 2023 Article: 82
