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circPTPN14 promotes renal fibrosis through its interaction with FUBP1 to enhance MYC transcription

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Abstract

CircRNAs are a class of single-stranded molecules with tissue/development-specific expression patterns. Increasing evidence demonstrates that circRNAs play important roles in physiological or pathological conditions. Here, we provide a brief discussion of circRNA in renal fibrosis.

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References

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Acknowledgements

This work was supported by Science and Technology Program of Sichuan Province (2022NSFSC0761, 2022ZYD0128, 2022YFS0046 and 2021YJ0444), Chengdu Medical College Research Foundation (KYPY22-02), and the 1.3.5 Project for Disciplines of Excellence, West China Hospital, Sichuan University (ZYGD20008).

Funding

Funding was supported by Sichuan Province Science and Technology Support Program (2022NSFSC0761, 2022ZYD0128, 2022YFS0046, 2021YJ0444), Chengdu Medical College Research Foundation (KYPY22-02), West China Hospital, Sichuan University (ZYGD20008).

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Author notes

  1. Jian-Kang Zhou and Jiao Li contributed equally to this work.

Authors and Affiliations

  1. Department of Pathology and Pathophysiology, School of Basic Medical Sciences, Chengdu Medical College, Chengdu, 610500, China

    Jian-Kang Zhou

  2. Laboratory of Molecular Oncology, Frontiers Science Center for Disease-Related Molecular Network, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China

    Jiao Li & Yong Peng

Authors
  1. Jian-Kang Zhou
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  2. Jiao Li
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  3. Yong Peng
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Contributions

JKZ and JL wrote the manuscript, and YP revised the manuscript.

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Correspondence to Jian-Kang Zhou or Yong Peng.

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Not applicable. This study does not involve experiments on humans and animals.

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Zhou, JK., Li, J. & Peng, Y. circPTPN14 promotes renal fibrosis through its interaction with FUBP1 to enhance MYC transcription. Cell. Mol. Life Sci. 80, 115 (2023). https://doi.org/10.1007/s00018-023-04749-0

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