Articles

1. Engineered platforms for mimicking cardiac development and drug screening

   • Madison Stiefbold
   • Haokang Zhang
   • Leo Q. Wan

   Review Open access 25 April 2024 Article: 197

   

2. Telomerase is essential for cardiac differentiation and sustained metabolism of human cardiomyocytes

   • Shambhabi Chatterjee
   • Megan Leach-Mehrwald
   • Christian Bär

   Original Article Open access 24 April 2024 Article: 196

   

3. Regulation of Notch signaling by non-muscle myosin II Zipper in Drosophila

   • Dipti Verma
   • Ankita Singh
   • Ashim Mukherjee

   Original Article Open access 24 April 2024 Article: 195

   

4. Recent advances in mechanisms ensuring the pairing, synapsis and segregation of XY chromosomes in mice and humans

   • Matteo Lampitto
   • Marco Barchi

   Review Open access 23 April 2024 Article: 194

   

5. The α-tubulin acetyltransferase ATAT1: structure, cellular functions, and its emerging role in human diseases

   • Angela Iuzzolino
   • Francesca Romana Pellegrini
   • Daniela Trisciuoglio

   Review Open access 23 April 2024 Article: 193

   

6. Involvement of the glymphatic/meningeal lymphatic system in Alzheimer’s disease: insights into proteostasis and future directions

   • Kaoru Yamada
   • Takeshi Iwatsubo

   Review Open access 23 April 2024 Article: 192

   

7. Flotillins affect LPS-induced TLR4 signaling by modulating the trafficking and abundance of CD14

   • Orest V. Matveichuk
   • Anna Ciesielska
   • Katarzyna Kwiatkowska

   Original Article Open access 23 April 2024 Article: 191

   

8. Dietary cysteine and methionine promote peroxisome elevation and fat loss by induction of CG33474 expression in Drosophila adipose tissue

   • Meng Liu
   • Li He

   Original Article Open access 22 April 2024 Article: 190

   

9. Adipose-derived stem cells promote glycolysis and peritoneal metastasis via TGF-β1/SMAD3/ANGPTL4 axis in colorectal cancer

   • Chaojun Zhu
   • Lan Teng
   • Qiuhua Lai

   Original Article Open access 21 April 2024 Article: 189

   

10. Vascular mimicry as a facilitator of melanoma brain metastasis

    • Olivia K. Provance
    • Victor O. Oria
    • Lucia B. Jilaveanu

    Original Article Open access 18 April 2024 Article: 188

    

11. Role of transient receptor potential ankyrin 1 in idiopathic pulmonary fibrosis: modulation of M2 macrophage polarization

    • Yi Yang
    • Zhenyu Xiao
    • Yuan Luo

    Original Article Open access 18 April 2024 Article: 187

    

12. Dodecyl creatine ester therapy: from promise to reality

    • Aloïse Mabondzo
    • Jiddeke van de Kamp
    • Saadet Mercimek-Andrews

    Visions and reflections Open access 17 April 2024 Article: 186

    

13. When DNA-damage responses meet innate and adaptive immunity

    • Jie Tong
    • Jiangwei Song
    • Chunfu Zheng

    Review Open access 17 April 2024 Article: 185

    

14. The impact of nanomaterials on autophagy across health and disease conditions

    • Ida Florance
    • Marco Cordani
    • Natarajan Chandrasekaran

    Review Open access 17 April 2024 Article: 184

    

15. RUNX transcription factors are essential in maintaining epididymal epithelial differentiation

    • Mervi Toriseva
    • Ida Björkgren
    • Petra Sipilä

    Original Article Open access 17 April 2024 Article: 183

    

16. Linc-NSC affects cell differentiation, apoptosis and proliferation in mouse neural stem cells and embryonic stem cells in vitro and in vivo

    • Lili Guo
    • Dan Zou
    • Ruxiang Xu

    Original Article Open access 14 April 2024 Article: 182

    

17. Functional myelin in cognition and neurodevelopmental disorders

    • Hasni Khelfaoui
    • Cristobal Ibaceta-Gonzalez
    • Maria Cecilia Angulo

    Review Open access 13 April 2024 Article: 181

    

18. Identification of the role of DAB2 and CXCL8 in uterine spiral artery remodeling in early-onset preeclampsia

    • Yu Liu
    • Lili Du
    • Jingsi Chen

    Original Article Open access 13 April 2024 Article: 180

    

19. Tumor-associated macrophage-derived exosomal miR21-5p promotes tumor angiogenesis by regulating YAP1/HIF-1α axis in head and neck squamous cell carcinoma

    • Quan Yan
    • Jing Liu
    • Lu Gao

    Original Article Open access 11 April 2024 Article: 179

    

20. Epigenomic insights into common human disease pathology

    • Christopher G. Bell

    Review Open access 11 April 2024 Article: 178

    

21. Sex differences in DNA methylation across gestation: a large scale, cross-cohort, multi-tissue analysis

    • Darina Czamara
    • Linda Dieckmann
    • Sonja Entringer

    Original Article Open access 10 April 2024 Article: 177

    

22. A novel fatty acid analogue triggers CD36–GPR120 interaction and exerts anti-inflammatory action in endotoxemia

    • Pierre-Marie Boutanquoi
    • Amira Sayed Khan
    • Naim Akhtar Khan

    Original Article Open access 10 April 2024 Article: 176

    

23. LncRNA CARMN inhibits abdominal aortic aneurysm formation and vascular smooth muscle cell phenotypic transformation by interacting with SRF

    • Shenrong Liu
    • Haobin Zhou
    • Zheng Huang

    Original Article Open access 10 April 2024 Article: 175

    

24. CCDC28A deficiency causes sperm head defects, reduced sperm motility and male infertility in mice

    • Hongbin Zhou
    • Zhihua Zhang
    • Lei Wang

    Original Article Open access 10 April 2024 Article: 174

    

25. PALB2-mutated human mammary cells display a broad spectrum of morphological and functional abnormalities induced by increased TGFβ signaling

    • Hanna Tuppurainen
    • Niina Laurila
    • Hellevi Peltoketo

    Original Article Open access 10 April 2024 Article: 173

    

26. Bioengineered MSC^Cxcr2 transdifferentiated keratinocyte-like cell-derived organoid potentiates skin regeneration through ERK1/2 and STAT3 signaling in diabetic wound

    • Subholakshmi Choudhury
    • Neha R. Dhoke
    • Amitava Das

    Original Article Open access 10 April 2024 Article: 172

    

27. The E3 ubiquitin ligase ITCH negatively regulates intercellular communication via gap junctions by targeting connexin43 for lysosomal degradation

    • Max Zachrisson Totland
    • Lars Mørland Knudsen
    • Edward Leithe

    Original Article Open access 10 April 2024 Article: 171

    

28. Metabolic profiling identifies Qrich2 as a novel glutamine sensor that regulates microtubule glutamylation and mitochondrial function in mouse sperm

    • Guohui Zhang
    • Juncen Guo
    • Wenming Xu

    Original Article Open access 10 April 2024 Article: 170

    

29. Rhes, a striatal enriched protein, regulates post-translational small-ubiquitin-like-modifier (SUMO) modification of nuclear proteins and alters gene expression

    • Oscar Rivera
    • Manish Sharma
    • Srinivasa Subramaniam

    Original Article Open access 08 April 2024 Article: 169

    

30. Kinesin KIF3A regulates meiotic progression and spindle assembly in oocyte meiosis

    • Jing-Cai Liu
    • Zhen-Nan Pan
    • Shao-Chen Sun

    Original Article Open access 08 April 2024 Article: 168

    

31. NFKBIZ regulates NFκB signaling pathway to mediate tumorigenesis and metastasis of hepatocellular carcinoma by direct interaction with TRIM16

    • Danfeng Guo
    • Ming Zhang
    • Wenzhi Guo

    Original Article Open access 06 April 2024 Article: 167

    

32. Unearthing FLVCR1a: tracing the path to a vital cellular transporter

    • Veronica Fiorito
    • Emanuela Tolosano

    Review Open access 06 April 2024 Article: 166

    

33. CRL4^DCAF13 E3 ubiquitin ligase targets MeCP2 for degradation to prevent DNA hypermethylation and ensure normal transcription in growing oocytes

    • Peipei Ren
    • Xiaomei Tong
    • Yin-Li Zhang

    Original Article Open access 05 April 2024 Article: 165

    

34. Aberrant splicing of Ca_V1.2 calcium channel induced by decreased Rbfox1 enhances arterial constriction during diabetic hyperglycemia

    • Wei Hou
    • Shumin Yin
    • Juejin Wang

    Original Article Open access 04 April 2024 Article: 164

    

35. iRhom2 regulates ectodomain shedding and surface expression of the major histocompatibility complex (MHC) class I

    • Matteo Calligaris
    • Donatella P. Spanò
    • Simone D. Scilabra

    Original Article Open access 04 April 2024 Article: 163

    

36. Phosphorylation of the compartmentalized PKA substrate TAF15 regulates RNA–protein interactions

    • Andreas Feichtner
    • Florian Enzler
    • Omar Torres-Quesada

    Original Article Open access 03 April 2024 Article: 162

    

37. Positive regulation of Vav1 by Themis controls CD4 T cell pathogenicity in a mouse model of central nervous system inflammation

    • Remi Marrocco
    • Isabelle Bernard
    • Abdelhadi Saoudi

    Original Article Open access 02 April 2024 Article: 161

    

38. EP300/CREBBP acetyltransferase inhibition limits steroid receptor and FOXA1 signaling in prostate cancer cells

    • Jasmin Huttunen
    • Niina Aaltonen
    • Ville Paakinaho

    Original Article Open access 02 April 2024 Article: 160

    

39. Peripheral T-cell responses of EphB2- and EphB3-deficient mice in a model of collagen-induced arthritis

    • Sara Montero-Herradón
    • Javier García-Ceca
    • Agustín G. Zapata

    Original Article Open access 01 April 2024 Article: 159

    

40. A novel gene-trap line reveals the dynamic patterns and essential roles of cysteine and glycine-rich protein 3 in zebrafish heart development and regeneration

    • Shuzhang Liang
    • Yating Zhou
    • Ruilin Zhang

    Original Article Open access 31 March 2024 Article: 158

    

41. Regulation and function of transposable elements in cancer genomes

    • Michael Lee Jr.
    • Syed Farhan Ahmad
    • Jian Xu

    Review Open access 31 March 2024 Article: 157

    

42. Unraveling the role of Xist in X chromosome inactivation: insights from rabbit model and deletion analysis of exons and repeat A

    • Mingming Liang
    • Lichao Zhang
    • Zhanjun Li

    Original Article Open access 29 March 2024 Article: 156

    

43. Aberrant activated Notch1 promotes prostate enlargement driven by androgen signaling via disrupting mitochondrial function in mouse

    • Jin-Wen Kang
    • Jia-Peng He
    • Ren-Wei Su

    Original Article Open access 28 March 2024 Article: 155

    

44. Discovery and verification of mmu_Circ_26986/hsa_Circ_0072463 as a potential biomarker and intervention target for sepsis-associated acute kidney injury

    • Xujun Peng
    • Huiling Li
    • Dongshan Zhang

    Original Article Open access 28 March 2024 Article: 154

    

45. De novo GRIN variants in M3 helix associated with neurological disorders control channel gating of NMDA receptor

    • Yuchen Xu
    • Rui Song
    • Stephen F. Traynelis

    Original Article Open access 28 March 2024 Article: 153

    

46. Macrophage re-programming by JAK inhibitors relies on MAFB

    • Baltasar López-Navarro
    • Miriam Simón-Fuentes
    • Amaya Puig-Kröger

    Original Article Open access 25 March 2024 Article: 152

    

47. Obesogenic diet in pregnancy disrupts placental iron handling and ferroptosis and stress signalling in association with fetal growth alterations

    • Jonas Zaugg
    • Jorge Lopez-Tello
    • Amanda N. Sferruzzi-Perri

    Original Article Open access 25 March 2024 Article: 151

    

48. The exon junction complex is required for DMD gene splicing fidelity and myogenic differentiation

    • Dylan Da Cunha
    • Julie Miro
    • Sylvie Tuffery-Giraud

    Original Article Open access 21 March 2024 Article: 150

    

49. cGAS-STING pathway mediates activation of dendritic cell sensing of immunogenic tumors

    • Guohao Li
    • Xiangqian Zhao
    • Qi Chen

    Review Open access 21 March 2024 Article: 149

    

50. The antiviral response triggered by the cGAS/STING pathway is subverted by the foot-and-mouth disease virus proteases

    • Miguel Ángel Sanz
    • Miryam Polo
    • Margarita Sáiz

    Original Article Open access 20 March 2024 Article: 148