Telomerase is essential for cardiac differentiation and sustained metabolism of human cardiomyocytes Shambhabi ChatterjeeMegan Leach-MehrwaldChristian Bär Original Article Open access 24 April 2024 Article: 196
Regulation of Notch signaling by non-muscle myosin II Zipper in Drosophila Dipti VermaAnkita SinghAshim Mukherjee Original Article Open access 24 April 2024 Article: 195
Recent advances in mechanisms ensuring the pairing, synapsis and segregation of XY chromosomes in mice and humans Matteo LampittoMarco Barchi Review Open access 23 April 2024 Article: 194
The α-tubulin acetyltransferase ATAT1: structure, cellular functions, and its emerging role in human diseases Angela IuzzolinoFrancesca Romana PellegriniDaniela Trisciuoglio Review Open access 23 April 2024 Article: 193
Involvement of the glymphatic/meningeal lymphatic system in Alzheimer’s disease: insights into proteostasis and future directions Kaoru YamadaTakeshi Iwatsubo Review Open access 23 April 2024 Article: 192
Flotillins affect LPS-induced TLR4 signaling by modulating the trafficking and abundance of CD14 Orest V. MatveichukAnna CiesielskaKatarzyna Kwiatkowska Original Article Open access 23 April 2024 Article: 191
Dietary cysteine and methionine promote peroxisome elevation and fat loss by induction of CG33474 expression in Drosophila adipose tissue Meng LiuLi He Original Article Open access 22 April 2024 Article: 190
Adipose-derived stem cells promote glycolysis and peritoneal metastasis via TGF-β1/SMAD3/ANGPTL4 axis in colorectal cancer Chaojun ZhuLan TengQiuhua Lai Original Article Open access 21 April 2024 Article: 189
Vascular mimicry as a facilitator of melanoma brain metastasis Olivia K. ProvanceVictor O. OriaLucia B. Jilaveanu Original Article Open access 18 April 2024 Article: 188
Role of transient receptor potential ankyrin 1 in idiopathic pulmonary fibrosis: modulation of M2 macrophage polarization Yi YangZhenyu XiaoYuan Luo Original Article Open access 18 April 2024 Article: 187
Dodecyl creatine ester therapy: from promise to reality Aloïse MabondzoJiddeke van de KampSaadet Mercimek-Andrews Visions and reflections Open access 17 April 2024 Article: 186
When DNA-damage responses meet innate and adaptive immunity Jie TongJiangwei SongChunfu Zheng Review Open access 17 April 2024 Article: 185
The impact of nanomaterials on autophagy across health and disease conditions Ida FloranceMarco CordaniNatarajan Chandrasekaran Review Open access 17 April 2024 Article: 184
RUNX transcription factors are essential in maintaining epididymal epithelial differentiation Mervi TorisevaIda BjörkgrenPetra Sipilä Original Article Open access 17 April 2024 Article: 183
Linc-NSC affects cell differentiation, apoptosis and proliferation in mouse neural stem cells and embryonic stem cells in vitro and in vivo Lili GuoDan ZouRuxiang Xu Original Article Open access 14 April 2024 Article: 182
Functional myelin in cognition and neurodevelopmental disorders Hasni KhelfaouiCristobal Ibaceta-GonzalezMaria Cecilia Angulo Review Open access 13 April 2024 Article: 181
Identification of the role of DAB2 and CXCL8 in uterine spiral artery remodeling in early-onset preeclampsia Yu LiuLili DuJingsi Chen Original Article Open access 13 April 2024 Article: 180
Tumor-associated macrophage-derived exosomal miR21-5p promotes tumor angiogenesis by regulating YAP1/HIF-1α axis in head and neck squamous cell carcinoma Quan YanJing LiuLu Gao Original Article Open access 11 April 2024 Article: 179
Epigenomic insights into common human disease pathology Christopher G. Bell Review Open access 11 April 2024 Article: 178
Sex differences in DNA methylation across gestation: a large scale, cross-cohort, multi-tissue analysis Darina CzamaraLinda DieckmannSonja Entringer Original Article Open access 10 April 2024 Article: 177
A novel fatty acid analogue triggers CD36–GPR120 interaction and exerts anti-inflammatory action in endotoxemia Pierre-Marie BoutanquoiAmira Sayed KhanNaim Akhtar Khan Original Article Open access 10 April 2024 Article: 176
LncRNA CARMN inhibits abdominal aortic aneurysm formation and vascular smooth muscle cell phenotypic transformation by interacting with SRF Shenrong LiuHaobin ZhouZheng Huang Original Article Open access 10 April 2024 Article: 175
CCDC28A deficiency causes sperm head defects, reduced sperm motility and male infertility in mice Hongbin ZhouZhihua ZhangLei Wang Original Article Open access 10 April 2024 Article: 174
PALB2-mutated human mammary cells display a broad spectrum of morphological and functional abnormalities induced by increased TGFβ signaling Hanna TuppurainenNiina LaurilaHellevi Peltoketo Original Article Open access 10 April 2024 Article: 173
Bioengineered MSCCxcr2 transdifferentiated keratinocyte-like cell-derived organoid potentiates skin regeneration through ERK1/2 and STAT3 signaling in diabetic wound Subholakshmi ChoudhuryNeha R. DhokeAmitava Das Original Article Open access 10 April 2024 Article: 172
The E3 ubiquitin ligase ITCH negatively regulates intercellular communication via gap junctions by targeting connexin43 for lysosomal degradation Max Zachrisson TotlandLars Mørland KnudsenEdward Leithe Original Article Open access 10 April 2024 Article: 171
Metabolic profiling identifies Qrich2 as a novel glutamine sensor that regulates microtubule glutamylation and mitochondrial function in mouse sperm Guohui ZhangJuncen GuoWenming Xu Original Article Open access 10 April 2024 Article: 170
Rhes, a striatal enriched protein, regulates post-translational small-ubiquitin-like-modifier (SUMO) modification of nuclear proteins and alters gene expression Oscar RiveraManish SharmaSrinivasa Subramaniam Original Article Open access 08 April 2024 Article: 169
Kinesin KIF3A regulates meiotic progression and spindle assembly in oocyte meiosis Jing-Cai LiuZhen-Nan PanShao-Chen Sun Original Article Open access 08 April 2024 Article: 168
NFKBIZ regulates NFκB signaling pathway to mediate tumorigenesis and metastasis of hepatocellular carcinoma by direct interaction with TRIM16 Danfeng GuoMing ZhangWenzhi Guo Original Article Open access 06 April 2024 Article: 167
Unearthing FLVCR1a: tracing the path to a vital cellular transporter Veronica FioritoEmanuela Tolosano Review Open access 06 April 2024 Article: 166
CRL4DCAF13 E3 ubiquitin ligase targets MeCP2 for degradation to prevent DNA hypermethylation and ensure normal transcription in growing oocytes Peipei RenXiaomei TongYin-Li Zhang Original Article Open access 05 April 2024 Article: 165
Aberrant splicing of CaV1.2 calcium channel induced by decreased Rbfox1 enhances arterial constriction during diabetic hyperglycemia Wei HouShumin YinJuejin Wang Original Article Open access 04 April 2024 Article: 164
iRhom2 regulates ectodomain shedding and surface expression of the major histocompatibility complex (MHC) class I Matteo CalligarisDonatella P. SpanòSimone D. Scilabra Original Article Open access 04 April 2024 Article: 163
Phosphorylation of the compartmentalized PKA substrate TAF15 regulates RNA–protein interactions Andreas FeichtnerFlorian EnzlerOmar Torres-Quesada Original Article Open access 03 April 2024 Article: 162
Positive regulation of Vav1 by Themis controls CD4 T cell pathogenicity in a mouse model of central nervous system inflammation Remi MarroccoIsabelle BernardAbdelhadi Saoudi Original Article Open access 02 April 2024 Article: 161
EP300/CREBBP acetyltransferase inhibition limits steroid receptor and FOXA1 signaling in prostate cancer cells Jasmin HuttunenNiina AaltonenVille Paakinaho Original Article Open access 02 April 2024 Article: 160
Peripheral T-cell responses of EphB2- and EphB3-deficient mice in a model of collagen-induced arthritis Sara Montero-HerradónJavier García-CecaAgustín G. Zapata Original Article Open access 01 April 2024 Article: 159
A novel gene-trap line reveals the dynamic patterns and essential roles of cysteine and glycine-rich protein 3 in zebrafish heart development and regeneration Shuzhang LiangYating ZhouRuilin Zhang Original Article Open access 31 March 2024 Article: 158
Regulation and function of transposable elements in cancer genomes Michael Lee Jr.Syed Farhan AhmadJian Xu Review Open access 31 March 2024 Article: 157
Unraveling the role of Xist in X chromosome inactivation: insights from rabbit model and deletion analysis of exons and repeat A Mingming LiangLichao ZhangZhanjun Li Original Article Open access 29 March 2024 Article: 156
Aberrant activated Notch1 promotes prostate enlargement driven by androgen signaling via disrupting mitochondrial function in mouse Jin-Wen KangJia-Peng HeRen-Wei Su Original Article Open access 28 March 2024 Article: 155
Discovery and verification of mmu_Circ_26986/hsa_Circ_0072463 as a potential biomarker and intervention target for sepsis-associated acute kidney injury Xujun PengHuiling LiDongshan Zhang Original Article Open access 28 March 2024 Article: 154
De novo GRIN variants in M3 helix associated with neurological disorders control channel gating of NMDA receptor Yuchen XuRui SongStephen F. Traynelis Original Article Open access 28 March 2024 Article: 153
Macrophage re-programming by JAK inhibitors relies on MAFB Baltasar López-NavarroMiriam Simón-FuentesAmaya Puig-Kröger Original Article Open access 25 March 2024 Article: 152
Obesogenic diet in pregnancy disrupts placental iron handling and ferroptosis and stress signalling in association with fetal growth alterations Jonas ZauggJorge Lopez-TelloAmanda N. Sferruzzi-Perri Original Article Open access 25 March 2024 Article: 151
The exon junction complex is required for DMD gene splicing fidelity and myogenic differentiation Dylan Da CunhaJulie MiroSylvie Tuffery-Giraud Original Article Open access 21 March 2024 Article: 150
cGAS-STING pathway mediates activation of dendritic cell sensing of immunogenic tumors Guohao LiXiangqian ZhaoQi Chen Review Open access 21 March 2024 Article: 149
The antiviral response triggered by the cGAS/STING pathway is subverted by the foot-and-mouth disease virus proteases Miguel Ángel SanzMiryam PoloMargarita Sáiz Original Article Open access 20 March 2024 Article: 148
Neonatal GABAergic transmission primes vestibular gating of output for adult spatial navigation Qiufen JiangKenneth Lap-Kei WuYing-Shing Chan Original Article Open access 19 March 2024 Article: 147
