Volume 44, Issue 2

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April 2022

Special Issue: Understanding the impact of aging on the susceptibility and response to COVID-19 infection

Issue Editors:

Elizabeth Sapey,
Kylie Belchamber

40 articles in this issue

SARS-CoV-2 interacts with renin-angiotensin system: impact on the central nervous system in elderly patients
Jorge Quarleri
M. Victoria Delpino
Review 14 February 2022 Pages: 547 - 565
Part of 1 collection:

Understanding the impact of aging on the susceptibility and response to COVID-19 infection
The elderly at risk: aldosterone as modulator of the immune response to SARS-CoV-2 infection
Pasquale Campana
Maria Emiliana Palaia
Dario Leosco
Original Article 05 November 2021 Pages: 567 - 572
Part of 1 collection:

Understanding the impact of aging on the susceptibility and response to COVID-19 infection
Premorbid aspirin use is not associated with lower mortality in older inpatients with SARS-CoV-2 pneumonia
Coralie Sullerot
Kevin Bouiller
On behalf of ESGIE (European Society of Clinical Microbiology, European Society of Clinical Microbiological and Infectious Diseases, Study Group for Infections in the Elderly)
Original Article 07 January 2022 Pages: 573 - 583
Part of 1 collection:

Understanding the impact of aging on the susceptibility and response to COVID-19 infection
Modeling of nursing care-associated airborne transmission of SARS-CoV-2 in a real-world hospital setting
Attila Nagy
Alpár Horváth
Veronika Müller
Original Article Open access 05 January 2022 Pages: 585 - 595
Part of 1 collection:

Understanding the impact of aging on the susceptibility and response to COVID-19 infection
A naturally hypersensitive porcine model may help understand the mechanism of COVID-19 mRNA vaccine-induced rare (pseudo) allergic reactions: complement activation as a possible contributing factor
László Dézsi
Tamás Mészáros
János Szebeni
Original Article Open access 11 February 2022 Pages: 597 - 618
Part of 1 collection:

Understanding the impact of aging on the susceptibility and response to COVID-19 infection
Omicron variant (B.1.1.529) of SARS-CoV-2: understanding mutations in the genome, S-glycoprotein, and antibody-binding regions
Manojit Bhattacharya
Ashish Ranjan Sharma
Chiranjib Chakraborty
Original Article 08 March 2022 Pages: 619 - 637
Part of 1 collection:

Understanding the impact of aging on the susceptibility and response to COVID-19 infection
New imaging tools for mouse models of osteoarthritis
S. Drevet
B. Favier
E. Brun
Review 07 February 2022 Pages: 639 - 650
Part of 1 collection:

Animal Models for Translational and Preclinical Geroscience Research
Obesity paradox in joint replacement for osteoarthritis — truth or paradox?
Setor K. Kunutsor
Michael R. Whitehouse
Ashley W. Blom
Opinion Paper Open access 27 August 2021 Pages: 651 - 659
Spatial transcriptomic analysis reveals inflammatory foci defined by senescent cells in the white matter, hippocampi and cortical grey matter in the aged mouse brain
Tamas Kiss
Ádám Nyúl-Tóth
Anna Csiszar
Original Article 31 January 2022 Pages: 661 - 681
Part of 1 collection:

White matter lesions in age-related cognitive decline: etiology, risk factors, prevention and repair
DNA damage-induced degradation of Sp1 promotes cellular senescence
Michelle L. Swift
Christian Sell
Jane Azizkhan-Clifford
Original Article Open access 22 September 2021 Pages: 683 - 698
Epigenetic clock and methylation studies in vervet monkeys
Anna J. Jasinska
Amin Haghani
Steve Horvath
Original Article Open access 30 September 2021 Pages: 699 - 717
Part of 1 collection:

Animal Models for Translational and Preclinical Geroscience Research
Distribution of 54 polygenic risk scores for common diseases in long lived individuals and their offspring
Sophia Gunn
Michael Wainberg
Paola Sebastiani
Original Article 04 February 2022 Pages: 719 - 729
Naked mole-rats maintain cardiac function and body composition well into their fourth decade of life
Emine Can
Megan Smith
Johannes Riegler
Original Article Open access 02 February 2022 Pages: 731 - 746
Part of 1 collection:

Animal Models for Translational and Preclinical Geroscience Research
Loss of aly/ALYREF suppresses toxicity in both tau and TDP-43 models of neurodegeneration
Rebecca L. Kow
Aristide H. Black
Brian C. Kraemer
Original Article 04 February 2022 Pages: 747 - 761
Part of 1 collection:

Bridging Geroscience and Neuroscience: Exploring Neurosurgical and Neurological Perspectives on Aging and Age-Related Diseases
Selective brain regional changes in lipid profile with human aging
Natalia Mota-Martorell
Pol Andrés-Benito
Reinald Pamplona
Original Article Open access 11 February 2022 Pages: 763 - 783
Part of 1 collection:

Bridging Geroscience and Neuroscience: Exploring Neurosurgical and Neurological Perspectives on Aging and Age-Related Diseases
Examination of pituitary adenylate cyclase-activating polypeptide in Parkinson’s disease focusing on correlations with motor symptoms
Daniel Pham
Beata Polgar
Andrea Tamas
Original Article Open access 26 February 2022 Pages: 785 - 803
Part of 1 collection:

Bridging Geroscience and Neuroscience: Exploring Neurosurgical and Neurological Perspectives on Aging and Age-Related Diseases
Cerebral venous congestion exacerbates cerebral microhemorrhages in mice
Adam Nyul-Toth
Gabor A. Fulop
Zoltan Ungvari
Original Article 06 January 2022 Pages: 805 - 816
Part of 2 collections:

White matter lesions in age-related cognitive decline: etiology, risk factors, prevention and repair

Bridging Geroscience and Neuroscience: Exploring Neurosurgical and Neurological Perspectives on Aging and Age-Related Diseases
Accelerated epigenetic aging and inflammatory/immunological profile (ipAGE) in patients with chronic kidney disease
Igor Yusipov
Elena Kondakova
Mikhail Ivanchenko
Original Article 02 March 2022 Pages: 817 - 834
Liver frailty and all-cause mortality in the older participants of the Salus in Apulia Study
Roberta Zupo
Fabio Castellana
Rodolfo Sardone
OriginalPaper 11 August 2021 Pages: 835 - 845
Cingulo-opercular and frontoparietal control network connectivity and executive functioning in older adults
Hanna K. Hausman
Cheshire Hardcastle
Adam J. Woods
Original Article 23 December 2021 Pages: 847 - 866
Part of 1 collection:

Advances in Neurostimulation in Aging: From Basic Science to Clinical Applications
Metabolic syndrome and Growth Differentiation Factor 15 in older adults
Adrián Carballo-Casla
Esther García-Esquinas
Rosario Ortolá
Original Article 07 May 2021 Pages: 867 - 880
Association of rs3027178 polymorphism in the circadian clock gene PER1 with susceptibility to Alzheimer’s disease and longevity in an Italian population
Maria Giulia Bacalini
Flavia Palombo
Aurelia Santoro
Original Article Open access 18 December 2021 Pages: 881 - 896
Strategies for handling missing data that improve Frailty Index estimation and predictive power: lessons from the NHANES dataset
Glen Pridham
Kenneth Rockwood
Andrew Rutenberg
Original Article 01 February 2022 Pages: 897 - 923
Associations between sociodemographic factors, health spending, disease burden, and life expectancy of older adults (70 + years old) in 22 countries in the Western Pacific Region, 1995–2019: estimates from the Global Burden of Disease (GBD) Study 2019
Alex Molassiotis
Stephen W. H. Kwok
Stefanos Tyrovolas
Original Article Open access 08 January 2022 Pages: 925 - 951
Old blood from heterochronic parabionts accelerates vascular aging in young mice: transcriptomic signature of pathologic smooth muscle remodeling
Tamas Kiss
Ádám Nyúl-Tóth
Zoltan Ungvari
Original Article 05 February 2022 Pages: 953 - 981
Part of 1 collection:

Cell Biology of Vascular Aging
Evaluation of a blood-based geroscience biomarker index in a randomized trial of caloric restriction and exercise in older adults with heart failure with preserved ejection fraction
Jamie N. Justice
Nicholas M. Pajewski
Dalane W. Kitzman
Original Article 10 January 2022 Pages: 983 - 995
Part of 1 collection:

Enhancing Health-span through Anti-Aging Dietary Interventions
Lower human defensin 5 in elderly people compared to middle-aged is associated with differences in the intestinal microbiota composition: the DOSANCO Health Study
Yu Shimizu
Kiminori Nakamura
Tokiyoshi Ayabe
Original Article Open access 08 June 2021 Pages: 997 - 1009
Proximal improvement and higher-order resting state network change after multidomain cognitive training intervention in healthy older adults
Cheshire Hardcastle
Hanna K. Hausman
Adam J. Woods
Original Article 08 March 2022 Pages: 1011 - 1027
Part of 1 collection:

Advances in Neurostimulation in Aging: From Basic Science to Clinical Applications
A small-molecule Psora-4 acts as a caloric restriction mimetic to promote longevity in C. elegans
Tesfahun Dessale Admasu
Diogo Barardo
Jan Gruber
Original Article 14 May 2021 Pages: 1029 - 1046
Part of 1 collection:

Enhancing Health-span through Anti-Aging Dietary Interventions
Maternal stress programs a demasculinization of glutamatergic transmission in stress-related brain regions of aged rats
Remy Verhaeghe
Vance Gao
Stefania Maccari
Original Article Open access 13 May 2021 Pages: 1047 - 1069
Part of 1 collection:

Animal Models for Translational and Preclinical Geroscience Research
Growth hormone increases DNA damage in ovarian follicles and macrophage infiltration in the ovaries
Tatiana D. Saccon
Monique T. Rovani
Augusto Schneider
Original Article 05 May 2021 Pages: 1071 - 1081
Using lipid profiling to better characterize metabolic differences in apolipoprotein E (APOE) genotype among community-dwelling older Black men
Megan M. Marron
Steven C. Moore
Anne B. Newman
Original Article 15 May 2021 Pages: 1083 - 1094
Dual effects of insulin resistance on mortality and function in non-diabetic older adults: findings from the Toledo Study of Healthy Aging
Leocadio Rodríguez-Mañas
Javier Angulo
Alan J. Sinclair
Original Article 01 June 2021 Pages: 1095 - 1108
Lipid and metabolite correlation networks specific to clinical and biochemical covariate show differences associated with sexual dimorphism in a cohort of nonagenarians
Francesca Di Cesare
Leonardo Tenori
Edoardo Saccenti
Original Article Open access 29 July 2021 Pages: 1109 - 1128
Extreme longevity variants at the FOXO3 locus may moderate FOXO3 isoform levels
Ryan Frankum
Tom S. O. Jameson
Lorna W. Harries
Original Article Open access 26 August 2021 Pages: 1129 - 1140
Part of 1 collection:

Understanding and overcoming the mechanisms driving age-related sarcopenia
Mediation of the APOE associations with Alzheimer’s and coronary heart diseases through body mass index and lipids
Yury Loika
Fan Feng
Alexander M. Kulminski
Original Article 23 September 2021 Pages: 1141 - 1156
Brain cellular senescence in mouse models of Alzheimer’s disease
Angela O. Dorigatti
Ruben Riordan
Viviana I. Perez
Short Communication 06 March 2022 Pages: 1157 - 1168
Correction to: Extreme longevity variants at the FOXO3 locus may moderate FOXO3 isoform levels
Ryan Frankum
Tom S. O. Jameson
Lorna W. Harries
Correction Open access 12 October 2021 Pages: 1169 - 1170
Correction to: Primary neuron and astrocyte cultures from postnatal Callithrix jacchus: a non-human primate in vitro model for research in neuroscience, nervous system aging, and neurological diseases of aging
Angela O. Dorigatti
Stacy A. Hussong
Veronica Galvan
Correction 02 February 2022 Pages: 1171 - 1171
Retraction Note to: Omega-3 fatty acid levels in red blood cell membranes and physical decline over 3 years: longitudinal data from the MAPT study
Bertrand Fougère
Sabine Goisser
MAPT Study Group
Retraction Note 05 January 2022 Pages: 1173 - 1173

Volume 44, Issue 2

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