Aging might augment reactive oxygen species (ROS) formation and affect reactive nitrogen species (RNS) level after myocardial ischemia/reperfusion in both humans and rats Qian FanMulei ChenMiaobing Liu OriginalPaper 12 May 2012 Pages: 1017 - 1026
Lifelong environmental enrichment in rats: impact on emotional behavior, spatial memory vividness, and cholinergic neurons over the lifespan Hayat HaratiAlexandra BarbelivienMonique Majchrzak OriginalPaper 17 May 2012 Pages: 1027 - 1043
Identification of the dichotomous role of age-related LCK in calorie restriction revealed by integrative analysis of cDNA microarray and interactome Daeui ParkEun Kyeong LeeHae Young Chung OriginalPaper 25 July 2012 Pages: 1045 - 1060
Late-life enalapril administration induces nitric oxide-dependent and independent metabolic adaptations in the rat skeletal muscle Emanuele MarzettiRiccardo CalvaniChristy S. Carter OriginalPaper 26 May 2012 Pages: 1061 - 1075
Age-related changes in cutaneous sensation in the healthy human hand Jocelyn L. BowdenPenelope A. McNulty OriginalPaper 04 June 2012 Pages: 1077 - 1089
Chronic caloric restriction partially protects against age-related alteration in serum metabolome Jennifer M. De GuzmanGinger KuIndu Kheterpal OriginalPaper 04 June 2012 Pages: 1091 - 1104
Type II TGFβ receptor modulates chondrocyte phenotype Catherine BaugéElise DuvalKarim Boumédiene OriginalPaper 01 June 2012 Pages: 1105 - 1116
A botanical containing freeze dried açai pulp promotes healthy aging and reduces oxidative damage in sod1 knockdown flies Mara LasloXiaoping SunSige Zou OriginalPaper 26 May 2012 Pages: 1117 - 1132
Curcumin-supplemented diets increase superoxide dismutase activity and mean lifespan in Drosophila Li-Rong ShenFa XiaoChao-Qiang Lai OriginalPaper 01 June 2012 Pages: 1133 - 1142
Caloric restriction-associated remodeling of rat white adipose tissue: effects on the growth hormone/insulin-like growth factor-1 axis, sterol regulatory element binding protein-1, and macrophage infiltration Yoshikazu ChujoNamiki FujiiYoshikazu Higami OriginalPaper 28 May 2012 Pages: 1143 - 1156
MiR-146a as marker of senescence-associated pro-inflammatory status in cells involved in vascular remodelling Fabiola OlivieriRaffaella LazzariniAntonio Domenico Procopio OriginalPaper 13 June 2012 Pages: 1157 - 1172
Weakness of whole muscles in mice deficient in Cu, Zn superoxide dismutase is not explained by defects at the level of the contractile apparatus Lisa M. LarkinMichael C. HanesSusan V. Brooks BriefCommunication 14 June 2012 Pages: 1173 - 1181
Reduced muscle oxidative capacity is independent of O2 availability in elderly people Gwenael LayecLuke J. HaselerRussell S. Richardson OriginalPaper 04 July 2012 Pages: 1183 - 1192
Interactive effects of sex, social environment, dietary restriction, and methionine on survival and reproduction in fruit flies Felix ZajitschekSusanne R. K. ZajitschekAlexei A. Maklakov OriginalPaper 15 July 2012 Pages: 1193 - 1204
Biomarkers of oxidative stress, antioxidant defence and inflammation are altered in the senescence-accelerated mouse prone 8 Banu BayramSibylle NikolaiGerald Rimbach OriginalPaper 06 July 2012 Pages: 1205 - 1217
Western-style diet modulates contractile responses to phenylephrine differently in mesenteric arteries from senescence-accelerated prone (SAMP8) and resistant (SAMR1) mice Francesc Jiménez-AltayóYara OnettiElisabet Vila OriginalPaper 10 July 2012 Pages: 1219 - 1234
Macrophages from elders are more permissive to intracellular multiplication of Mycobacterium tuberculosis José M. Guerra-LasoSandra González-GarcíaOctavio M. Rivero-Lezcano OriginalPaper 12 July 2012 Pages: 1235 - 1250
A role for c-Abl in cell senescence and spontaneous immortalization Man ZhangLili LiBaojie Li OriginalPaper 13 July 2012 Pages: 1251 - 1262
Thymus fat as an attractive source of angiogenic factors in elderly subjects with myocardial ischemia Leticia Coín AragüezMora MurriRajaa El Bekay OriginalPaper 11 May 2012 Pages: 1263 - 1275
Tryptophan-enriched cereal intake improves nocturnal sleep, melatonin, serotonin, and total antioxidant capacity levels and mood in elderly humans R. BravoS. MatitoC. Barriga OriginalPaper 24 May 2012 Pages: 1277 - 1285
Specific saccade deficits in patients with Alzheimer’s disease at mild to moderate stage and in patients with amnestic mild cognitive impairment Qing YangTao WangZoi Kapoula OriginalPaper 11 May 2012 Pages: 1287 - 1298
Age-related changes in joint coordination during balance recovery Wei-Li HsuLi-Shan ChouMarjorie Woollacott OriginalPaper 18 May 2012 Pages: 1299 - 1309
Oral supplementation with Lactobacillus delbrueckii subsp. bulgaricus 8481 enhances systemic immunity in elderly subjects Marco Antonio Moro-GarcíaRebeca Alonso-AriasCarlos López-Larrea OriginalPaper 30 May 2012 Pages: 1311 - 1326
Effects of aging and sex on voluntary activation and peak relaxation rate of human elbow flexors studied with motor cortical stimulation Joery P. MolenaarChris J. McNeilSimon C. Gandevia OriginalPaper 01 June 2012 Pages: 1327 - 1337
Ageing of internal models: from a continuous to an intermittent proprioceptive control of movement Matthieu P. BoisgontierVincent Nougier OriginalPaper 26 May 2012 Pages: 1339 - 1355
MAP3K7 and GSTZ1 are associated with human longevity: a two-stage case–control study using a multilocus genotyping Fausta Di CianniDaniele CampaGiuseppina Rose OriginalPaper 11 May 2012 Pages: 1357 - 1366
Association of heat shock proteins with all-cause mortality L. BroerE. W. DemerathC. M. van Duijn OriginalPaper Open access 04 May 2012 Pages: 1367 - 1376
Adiposity to muscle ratio predicts incident physical limitation in a cohort of 3,153 older adults—an alternative measurement of sarcopenia and sarcopenic obesity Tung Wai AuyeungJenny Shun Wah LeeJean Woo OriginalPaper 22 May 2012 Pages: 1377 - 1385
Lower proportion of naïve peripheral CD8+ T cells and an unopposed pro-inflammatory response to human Cytomegalovirus proteins in vitro are associated with longer survival in very elderly people Evelyna DerhovanessianAndrea B. MaierGraham Pawelec OriginalPaper Open access 04 June 2012 Pages: 1387 - 1399
Persistence of the effect of birth size on dysglycaemia and type 2 diabetes in old age: AGES-Reykjavik Study Mikaela B. von BonsdorffMajon Mullerfor the Age, Gene/Environment Susceptibility-Reykjavik Study Investigators OriginalPaper 16 May 2012 Pages: 1401 - 1409
Decreased oxidant profile and increased antioxidant capacity in naturally postmenopausal women V. J. VictorinoC. PanisR. Cecchini OriginalPaper 28 May 2012 Pages: 1411 - 1421
Association of sleep quality and dementia among long-lived Chinese older adults Yue JirongHuang ChangquanDong Bi-Rong OriginalPaper 06 June 2012 Pages: 1423 - 1432
Prognostic value of cardiovascular disease status: the Leiden 85-plus study Petra G. van PeetYvonne M. DrewesWouter de Ruijter OriginalPaper Open access 04 July 2012 Pages: 1433 - 1444
Mitochondrial J haplogroup is associated with lower blood pressure and anti-oxidant status: findings in octo/nonagenarians from the BELFAST Study Irene Maeve ReaSusan E. McNerlanOwen A. Ross OriginalPaper Open access 10 July 2012 Pages: 1445 - 1456
Validating a widely used measure of frailty: are all sub-components necessary? Evidence from the Whitehall II cohort study Kim BouillonSeverine SabiaG. David Batty OriginalPaper Open access 08 July 2012 Pages: 1457 - 1465
Linkage and association of successful aging to the 6q25 region in large Amish kindreds Digna R. Velez EdwardsJohn R. GilbertWilliam K. Scott OriginalPaper 07 July 2012 Pages: 1467 - 1477
Chronic psychosocial stress: does it modulate immunity to the influenza vaccine in Hong Kong Chinese elderly caregivers? Samuel Yeung Shan WongChun Kwok WongJean Woo OriginalPaper 08 July 2012 Pages: 1479 - 1493
Dietary intake of eicosapentaenoic and docosahexaenoic acids is linked to gray matter volume and cognitive function in elderly Olga E. TitovaPer SjögrenChristian Benedict OriginalPaper Open access 13 July 2012 Pages: 1495 - 1505
Association of age-related changes in circulating intermediary lipid metabolites, inflammatory and oxidative stress markers, and arterial stiffness in middle-aged men Ji Young KimOh Yoen KimJong Ho Lee OriginalPaper Open access 18 July 2012 Pages: 1507 - 1519