A novel pregnene analogs: synthesis, cytotoxicity on prostate cancer of PC-3 and LNCPa-AI cells and in silico molecular docking study Nabeel A. Abdul-RidaAli M. FarhanMing-Fong Lin Original Article 31 January 2020 Pages: 661 - 671
New nicotinic acid-based 3,5-diphenylpyrazoles: design, synthesis and antihyperlipidemic activity with potential NPC1L1 inhibitory activity Mai E. ShomanMoustafa O. AboelezOmar M. Elhady Original Article 17 February 2020 Pages: 673 - 686
DNA interaction, in vivo and in vitro cytotoxicity, reactive oxygen species, lipid peroxidation of –N, S donor Re(I) metal complexes Reena R. VarmaJuhee G. PandyaMohan N. Patel Original Article 31 January 2020 Pages: 687 - 699
Dipolar cycloaddition strategy for three-component synthesis of chromeno[3′,4′:3,4]pyrido[2,1-a]isoquinoline derivatives Abdolali AlizadehParinaz JamalMojtaba Khanpour Original Article 01 February 2020 Pages: 701 - 710
Design, synthesis, crystal structure and in vitro antimicrobial activity of novel 1,2,4-triazolo[1,5-a]pyrimidine-containing quinazolinone derivatives Huan DuMuhan DingXiaoping Bao Original Article 31 January 2020 Pages: 711 - 722
Novel quinolinone–pyrazoline hybrids: synthesis and evaluation of antioxidant and lipoxygenase inhibitory activity Ioanna KostopoulouAntonia DiassakouAnastasia Detsi Original Article 17 February 2020 Pages: 723 - 740
Prediction model of human ABCC2/MRP2 efflux pump inhibitors: a QSAR study Minh-Tri LeThien-Vy PhanKhac-Minh Thai Original Article 11 February 2020 Pages: 741 - 751
Design, synthesis and evaluation of 3-hydroxypyridin-4-ones as inhibitors of catechol-O-methyltransferase Johannie de BeerJacobus P. PetzerAnél Petzer Original Article 27 February 2020 Pages: 753 - 762
Synthesis, characterization, antimicrobial, antioxidant and computational evaluation of N-acyl-morpholine-4-carbothioamides Hamid AzizAamer SaeedFarukh Jabeen Original Article 25 February 2020 Pages: 763 - 776
Synthesis of thia- and thioxo-tetraazaspiro[4.4]nonenones from nitrile imines and arylidenethiohydantoins Issa YavariZohreh TaheriMohammad R. Halvagar Original Article 25 February 2020 Pages: 777 - 785
Hydrazine clubbed 1,3-thiazoles as potent urease inhibitors: design, synthesis and molecular docking studies Pervaiz Ali ChannarAamer SaeedJamshed Iqbal Original Article 24 February 2020 Pages: 1 - 13
Data science-driven analyses of drugs inducing hypertension as an adverse effect Reetu Sharma Original Article 15 May 2020 Pages: 801 - 810
Design, synthesis and evaluation of new chromone-derived aminophosphonates as potential acetylcholinesterase inhibitor Sarfaraz ShaikhPratik DhavanB. L. Jadhav Original Article 02 March 2020 Pages: 811 - 825
Distinguishing drug/non-drug-like small molecules in drug discovery using deep belief network Seyed Aghil HooshmandSadegh Azimzadeh JamalkandiAli Masoudi-Nejad Original Article 19 March 2020 Pages: 827 - 838
Synthesis of triazolotriazine derivatives as c-Met inhibitors Yuting GuoXia PengWenhu Duan Original Article 10 March 2020 Pages: 839 - 846
Modeling and insights into molecular basis of low molecular weight respiratory sensitizers Xueyan CuiRui YangXiao Li Original Article 12 March 2020 Pages: 847 - 859
Design, synthesis and evaluation of dihydrotriazine derivatives-bearing 5-aryloxypyrazole moieties as antibacterial agents Tian-Yi ZhangChun-Shi LiXue-Kun Liu Original Article 14 March 2020 Pages: 861 - 876
Design and synthesis of 4,5-diphenyl-imidazol-1,2,3-triazole hybrids as new anti-diabetic agents: in vitro α-glucosidase inhibition, kinetic and docking studies Mohammad Sadegh AsgariMaryam Mohammadi-KhanaposhtaniBagher Larijani Original Article 18 March 2020 Pages: 877 - 888
Synthesis of the quinazolinone derivatives using an acid-functionalized magnetic silica heterogeneous catalyst in terms of green chemistry Saeid Ahmadizadeh ShendyMirzaagha BabazadehMoosa Es’haghi Original Article 20 February 2020 Pages: 889 - 897
Drug design by machine-trained elastic networks: predicting Ser/Thr-protein kinase inhibitors’ activities Cyrus Ahmadi ToussiJavad HaddadniaChérif F. Matta Original Article 28 March 2020 Pages: 899 - 909
A system-level approach to investigate alloxan-induced toxicity in microtubule-binding protein to lead type 2 diabetes mellitus Paramashivam Sathish KumarNarayanan Dhiraviam Kannan Original Article 26 March 2020 Pages: 911 - 924
One-pot synthesis of dihydro-8H acenaphtho[1′,2′:4,5]pyrrolo[1,2-a]imidazole-diol derivatives Masoud Mohammadi ValaMohammad BayatYadollah Bayat Original Article 08 April 2020 Pages: 925 - 935
N-Benzylation of 6-aminoflavone by reductive amination and efficient access to some novel anticancer agents via topoisomerase II inhibition Nitin M. ThoratAniket P. SarkateShankar R. Thopate Original Article 05 April 2020 Pages: 937 - 948
Introducing a pyrazolopyrimidine as a multi-tyrosine kinase inhibitor, using multi-QSAR and docking methods Asrin BahmaniHamid TanzadehpanahMassoud Saidijam Original Article 16 April 2020 Pages: 949 - 965
Synthesis and antitumor evaluation of (aryl)methyl-amine derivatives of dehydroabietic acid-based B ring-fused-thiazole as potential PI3K/AKT/mTOR signaling pathway inhibitors Nai-Yuan ChenYu-Lan XieCui-Ping Li Original Article 15 April 2020 Pages: 967 - 979
One-pot sequential coupling reactions as a new practical protocol for the synthesis of unsymmetrical 2,3-diethynyl quinoxalines and 4-ethynyl-substituted pyrrolo[1,2-a]quinoxalines Ali KeivanlooSaeed LashkariSima Abbaspour Original Article 16 April 2020 Pages: 981 - 993
Synthesis, β-glucuronidase inhibition and molecular docking studies of cyano-substituted bisindole hydrazone hybrids Obaidurahman AbidSyahrul ImranJuliana Yusoff Original Article 16 April 2020 Pages: 995 - 1009
Synthesis, computational study and cytotoxicity of 4-hydroxycoumarin-derived imines/enamines Samaneh VaseghiMohammad YousefiSaeed Emami Original Article 22 April 2020 Pages: 1011 - 1024
Design, synthesis, and anticancer activity of novel 4-thiazolidinone-phenylaminopyrimidine hybrids Aslı TüreMustafa Ergülİlkay Küçükgüzel Original Article 23 April 2020 Pages: 1025 - 1050
Structure–activity relationship study of DEL-22379: ERK dimerization inhibitors with increased safety Yang YangYuanzheng ZhouYoufu Luo Original Article 06 May 2020 Pages: 1051 - 1075
Molecular modeling and LC–MS-based metabolomics of a glutamine-valproic acid (Gln-VPA) derivative on HeLa cells M. J. Fragoso-VázquezD. Méndez-LunaJ. Correa-Basurto Original Article 24 April 2020 Pages: 1077 - 1089
Pharmacophore-based designing of putative ROS-1 targeting agents for NSCLC Disha PathakShalki ChoudharyOm Silakari Short Communication 30 January 2020 Pages: 1091 - 1102
Metal-free visible-light-mediated organophotoredox catalysis: synthesis of 3-functionalized indole via C–C, C–N bond formation Neetu YadavMohd Danish AnsariI. R. Siddiqui Short Communication 03 February 2020 Pages: 1103 - 1109
Synthesis and evaluation of antitumor activity of dibenzodiazepine derivatives Ke CaoJianwei YanTiantian Yin Short Communication 19 February 2020 Pages: 1111 - 1122
Solvent-free synthesis of isoindolo[2,1-c]pyrazolo[1,5-a]quinazoline and pyrazolo[5′,1′:2,3]pyrimido[6,1-a]isoindol derivatives through a one-pot three-component reaction Meysam Alizadeh-KouzehrashAbbas Rahmati Short Communication 19 February 2020 Pages: 1123 - 1130
Transition metal-free NaOH-catalyzed hydration of nitriles to primary amides in NH3·H2O–DMSO mixture Nan WangPeilong MaJie Zhang Short Communication 22 February 2020 Pages: 1131 - 1136
Pesticides, cosmetics, drugs: identical and opposite influences of various molecular features as measures of endpoints similarity and dissimilarity Andrey A. ToropovAlla P. ToropovaEmilio Benfenati Short Communication 23 April 2020 Pages: 1137 - 1144
The status of isocyanide-based multi-component reactions in Iran (2010–2018) Ahmad ShaabaniReza MohammadianSiamak Javanbakht Comprehensive review 18 February 2020 Pages: 1145 - 1210
Recent development in the synthesis of heterocycles by 2-naphthol-based multicomponent reactions Ankita Chaudhary Comprehensive review 23 March 2020 Pages: 1211 - 1245
Calix[4]API-s: fully functionalized calix[4]arene-based facial active pharmaceutical ingredients Fazel Nasuhi Pur Short review 31 January 2020 Pages: 1247 - 1258
