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Solvent-free synthesis of isoindolo[2,1-c]pyrazolo[1,5-a]quinazoline and pyrazolo[5′,1′:2,3]pyrimido[6,1-a]isoindol derivatives through a one-pot three-component reaction

Molecular Diversity volume 25, pages 1123–1130 (2021)Cite this article

Abstract

Some 5-substituted 3-aminopyrazoles were used for the synthesis of isoindolo[2,1-c]pyrazolo[1,5-a]quinazoline and pyrazolo[5′,1′:2,3]pyrimido[6,1-a]isoindol derivatives via a mild and efficient one-pot three-component reaction with 2-formylbenzoic acid and different CH-acids under solvent-free condition.

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Acknowledgements

We gratefully acknowledge financial support from the Research Council of the University of Isfahan.

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  1. Department of Chemistry, University of Isfahan, P. O. Box 81746-73441, Isfahan, Iran

    Meysam Alizadeh-Kouzehrash & Abbas Rahmati

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  1. Meysam Alizadeh-Kouzehrash
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  2. Abbas Rahmati
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Correspondence to Abbas Rahmati.

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Alizadeh-Kouzehrash, M., Rahmati, A. Solvent-free synthesis of isoindolo[2,1-c]pyrazolo[1,5-a]quinazoline and pyrazolo[5′,1′:2,3]pyrimido[6,1-a]isoindol derivatives through a one-pot three-component reaction. Mol Divers 25, 1123–1130 (2021). https://doi.org/10.1007/s11030-020-10052-y

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Keywords

  • Multicomponent reactions
  • Heterocyclic compounds
  • Isoindoline
  • Pyrazole