Metal-induced toxicity, carcinogenesis, mechanisms and cellular responses Stephen S. LeonardJacquelyn J. BowerXianglin Shi OriginalPaper Pages: 3 - 10
Toxicokinetic and genomic analysis of chronic arsenic exposure in multidrug-resistance mdr1a/1b(−/−) double knockout mice Yaxiong XieJie LiuMichael P. Waalkes OriginalPaper Pages: 11 - 18
Arsenite induces p70S6K1 activation and HIF-1α expression in prostate cancer cells Heath D. SkinnerXiao-song ZhongBing-Hua Jiang OriginalPaper Pages: 19 - 23
p53 Expression in circulating lymphocytes of non-melanoma skin cancer patients from an arsenic contaminated region in Mexico. A pilot study Ana M. SalazarEmma Calderón-ArandaPatricia Ostrosky-Wegman OriginalPaper Pages: 25 - 31
Arsenite induces HIF-1α and VEGF through PI3K, Akt and reactive oxygen species in DU145 human prostate carcinoma cells Ning GaoLiqin ShenBing-Hua Jiang OriginalPaper Pages: 33 - 45
Arsenic toxicity, mutagenesis, and carcinogenesis – a health risk assessment and management approach Paul B. TchounwouJose A. CentenoAnita K. Patlolla OriginalPaper Pages: 47 - 55
Molecular mechanisms of arsenic carcinogenesis Chuanshu HuangQingdong KeXianglin Shi OriginalPaper Pages: 57 - 66
Oxidative mechanism of arsenic toxicity and carcinogenesis Honglian ShiXianglin ShiKe Jian Liu OriginalPaper Pages: 67 - 78
Variability in sensitivity to arsenite does not correlate with arsenic accumulation rate in normal human lymphoblasts Ping LiAhmed N. UddinToby G. Rossman OriginalPaper Pages: 79 - 85
The gender differences in health effects of environmental cadmium exposure and potential mechanisms Muneko NishijoSoisungwan SatarugKeiko Aoshima OriginalPaper Pages: 87 - 92
Up-regulation of expression of translation factors – a novel molecular mechanism for cadmium carcinogenesis Pius JosephYi-Xiong LeiTong-man Ong OriginalPaper Pages: 93 - 101
Telomerase-mediated lifespan extension of human bronchial cells does not affect hexavalent chromium-induced cytotoxicity or genotoxicity Sandra S. WiseLynne W. ElmoreJohn Pierce Wise Sr OriginalPaper Pages: 103 - 112
Crystalline and water soluble CR(4+) and CR(5+:) model compounds for chromium toxicity studies Chris M. RamseyNaresh S. Dalal OriginalPaper Pages: 113 - 118
Role of reactive oxygen species and Cr(VI) in Ras-mediated signal transduction Suwei WangStephen S. LeonardXianglin Shi OriginalPaper Pages: 119 - 127
NF-κB prevents cells from undergoing Cr(VI)-induced apoptosis Suwei WangFei ChenLuo Jia OriginalPaper Pages: 129 - 137
Induction of pro-apoptotic and cell cycle-inhibiting genes in chromium (VI)-treated human lung fibroblasts: Lack of effect of ERK Susan CeryakCarla ZingarielloSteven R. Patierno OriginalPaper Pages: 139 - 149
Mechanisms of chromium-induced suppression of RNA synthesis in cellular and cell-free systems: Relationship to RNA polymerase arrest Jian XuFrancis C.R. ManningSteven R. Patierno OriginalPaper Pages: 151 - 160
Lead-induced cytotoxicity and transcriptional activation of stress genes in human liver carcinoma (HepG2) cells Paul B. TchounwouClement G. YedjouElaine Shen OriginalPaper Pages: 161 - 170
PbCrO4 mediates cellular responses via reactive oxygen species Stephen S. LeonardJenny R· RobertsXianglin Shi OriginalPaper Pages: 171 - 179
Genetic and cellular mechanisms in chromium and nickel carcinogenesis considering epidemiologic findings Arthur ChiuA.J. KatzXianglin Shi OriginalPaper Pages: 181 - 194
Reduced Fhit protein expression in nickel-transformed mouse cells and in nickel-induced murine sarcomas Renata KowaraKonstantin SalnikowKazimierz S. Kasprzak OriginalPaper Pages: 195 - 202
Molecular biology of nickel carcinogenesis: Identification of differentially expressed genes in morphologically transformed C3H10T1/2 Cl 8 mouse embryo fibroblast cell lines induced by pecific insoluble nickel compounds Rini VermaJamuna RamnathJoseph R. Landolph OriginalPaper Pages: 203 - 216
Activation of a PKC is required for vanadate-induced phosphorylation of protein kinase B (Akt), but not p70S6k in mouse epidermal JB6 cells Jingxia LiSujatha DokkaChuanshu Huang OriginalPaper Pages: 217 - 225
Vanadate activated PI3K and Akt and promoted S phase entry Zhuo ZhangNing GaoXianglin Shi OriginalPaper Pages: 227 - 237
The role of phosphatidylinositol-3 kinase in vanadate-promoted S phase entry Zhuo ZhangNing GaoXianglin Shi OriginalPaper Pages: 239 - 245
Effect of the militarily-relevant heavy metals, depleted uranium and heavy metal tungsten-alloy on gene expression in human liver carcinoma cells (HepG2) Alexandra C. MillerKia BrooksNatalie Page OriginalPaper Pages: 247 - 256
Metal composition and solubility determine lung toxicity induced by residual oil fly ash collected from different sites within a power plant James M. AntoniniMichael D. TaylorJenny R. Roberts OriginalPaper Pages: 257 - 265
