1. Preface

   • Barry I. Posner
   • Ashok K. Srivastava

   OriginalPaper Pages: 1 - 2

2. The IRS-signalling system: A network of docking proteins that mediate insulin action

   • Morris F. White

   OriginalPaper Pages: 3 - 11

3. Role of binding proteins to IRS-1 in insulin signalling

   • Wataru Ogawa
   • Takashi Matozaki
   • Masato Kasuga

   OriginalPaper Pages: 13 - 22

4. Insulin regulation of the Ras activation/inactivation cycle

   • Brian P. Ceresa
   • Jeffrey E. Pessin

   OriginalPaper Pages: 23 - 29

5. Insulin signal transduction through protein kinase cascades

   • Joseph Avruch

   OriginalPaper Pages: 31 - 48

6. Protein phosphatase-1 and insulin action

   • Louis Ragolia
   • Najma Begum

   OriginalPaper Pages: 49 - 58

7. Insulin receptor internalization and signalling

   • Gianni M. Di Guglielmo
   • Patricia C. Baass
   • John J.M. Bergeron

   OriginalPaper Pages: 59 - 63

8. Spatial determinants of specificity in insulin action

   • Cynthia Corley Mastick
   • Matthew J. Brady
   • Alan R. Saltiel

   OriginalPaper Pages: 65 - 71

9. Binding of SH2 containing proteins to the insulin receptor: A new way for modulating insulin signalling

   • Feng Liu
   • Richard A. Roth

   OriginalPaper Pages: 73 - 78

10. Insulin receptor-associated protein tyrosine phosphatase(s): Role in insulin action

    • Paul G. Drake
    • Barry I. Posner

    OriginalPaper Pages: 79 - 89

11. Regulation of the insulin signalling pathway by cellular protein-tyrosine phosphatases

    • Barry J. Goldstein
    • Faiyaz Ahmad
    • Wei-Ren Zhang

    OriginalPaper Pages: 91 - 99

12. Protein-tyrosine phosphatase-1B acts as a negative regulator of insulin signal transduction

    • John C.H. Byon
    • Anasua B. Kusari
    • Jyotirmoy Kusari

    OriginalPaper Pages: 101 - 108

13. Multifunctional actions of vanadium compounds on insulin signaling pathways: Evidence for preferential enhancement of metabolic versus mitogenic effects

    • I. George Fantus
    • Evangelia Tsiani

    OriginalPaper Pages: 109 - 119

14. Regulation of the Na⁺/K⁺-ATPase by insulin: Why and how?

    • Gary Sweeney
    • Amira Klip

    OriginalPaper Pages: 121 - 133

15. Potential mechanism(s) involved in the regulation of glycogen synthesis by insulin

    • Ashok K. Srivastava
    • Sanjay K. Pandey

    OriginalPaper Pages: 135 - 141

16. Metabolic and therapeutic lessons from genetic manipulation of GLUT4

    • Ellen B. Katz

    OriginalPaper Pages: 143 - 152

17. Insulin action in skeletal muscle from patients with NIDDM

    • Juleen R. Zierath
    • Anna Krook
    • Harriet Wallberg-Henriksson

    OriginalPaper Pages: 153 - 160

18. Genetic manipulation of insulin action and β-cell function in mice

    • Betty Lamothe
    • Bertrand Duvillié
    • Rajiv L. Joshi

    OriginalPaper Pages: 161 - 168

19. TNF-α and insulin resistance: Summary and future prospects

    • Pascal Peraldi
    • Bruce Spiegelman

    OriginalPaper Pages: 169 - 175

20. Membrane glycoprotein PC-1 and insulin resistance

    • Ira D. Goldfine
    • Betty A. Maddux
    • G. Lynis Dohm

    OriginalPaper Pages: 177 - 184

21. Insulin action on protein phosphatase-1 activation is enhanced by the antidiabetic agent pioglitazone in cultured diabetic hepatocytes

    • Subbiah Pugazhenthi
    • Ramji L. Khandelwal

    OriginalPaper Pages: 185 - 191