Evaluation of false positive rate based on exposure–response analyses for two compounds in fixed-dose combination products Hao ZhuYaning Wang OriginalPaper 06 September 2011 Pages: 671 - 696
A hidden Markov model to assess drug-induced sleep fragmentation in the telemetered rat C. DiackO. AckaertD. Fairman OriginalPaper Open access 10 September 2011 Pages: 697 - 711
Mechanism-based population modelling for assessment of L-cell function based on total GLP-1 response following an oral glucose tolerance test Jonas B. MøllerWilliam J. JuskoSteen H. Ingwersen OriginalPaper 16 September 2011 Pages: 713 - 725
Non-linear mixed effects modeling of antiretroviral drug response after administration of lopinavir, atazanavir and efavirenz containing regimens to treatment-naïve HIV-1 infected patients Daniel RöshammarUlrika S. H. SimonssonMagnus Gisslén OriginalPaper 02 October 2011 Pages: 727 - 742
The influence of distributional kinetics into a peripheral compartment on the pharmacokinetics of substrate partitioning between blood and brain tissue Jeannie M. PadowskiGary M. Pollack OriginalPaper 09 October 2011 Pages: 743 - 767
Population pharmacokinetic–pharmacodynamic–disease progression model for effects of anakinra in Lewis rats with collagen-induced arthritis Dongyang LiuHoi-Kei LonWilliam J. Jusko OriginalPaper 16 October 2011 Pages: 769 - 786
Modeling red blood cell survival data Julia KorellFrederiek E. VosStephen B. Duffull OriginalPaper 14 October 2011 Pages: 787 - 801
Model-based determination of abatacept exposure in support of the recommended dose for Japanese rheumatoid arthritis patients Mayumi HasegawaYasuhiko ImaiAmit Roy OriginalPaper 15 October 2011 Pages: 803 - 832
Extending the latent variable model for extra correlated longitudinal dichotomous responses Matthew M. HutmacherJonathan L. French OriginalPaper 22 October 2011 Pages: 833 - 859
Automatic data binning for improved visual diagnosis of pharmacometric models Marc LavielleKevin Bleakley OriginalPaper 26 October 2011 Pages: 861 - 871
Coping with time scales in disease systems analysis: application to bone remodeling Stephan SchmidtTeun M. PostMeindert Danhof OriginalPaper Open access 26 October 2011 Pages: 873 - 900