1. A mathematical model for dynamics of cardiovascular drug action: Application to intravenous dihydropyridines in healthy volunteers

   • Patrice Francheteau
   • Jean -Louis Steimer
   • Claude Dubray

   OriginalPaper 01 October 1993 Pages: 489 - 514

2. Simultaneous pharmacodynamic modeling of the non-steady-state effects of three oral doses of 1,3-glyceryl dinitrate upon blood pressure in healthy volunteers

   • Mark Gumbleton
   • Leslie Z. Benet

   OriginalPaper 01 October 1993 Pages: 515 - 532

3. Pharmacokinetics and pharmacodynamics of nitroglycerin and its dinitrate metabolites in conscious dogs: Intravenous infusion studies

   • Frank W. Lee
   • Tomas Salmonson
   • Leslie Z. Benet

   OriginalPaper 01 October 1993 Pages: 533 - 550

4. A physiological and system analysis hybrid pharmacokinetic model to characterize carbon tetrachloride blood concentrations following administration in different oral vehicles

   • James M. Gallo
   • L. L. Cheung
   • William R. Gillespie

   OriginalPaper 01 October 1993 Pages: 551 - 574

5. Targeting anticancer drugs to the brain: II. Physiological pharmacokinetic model of oxantrazole following intraarterial administration to rat glioma-2 (RG-2) bearing rats

   • James M. Gallo
   • Peter Varkonyi
   • Dennis R. Groothius

   OriginalPaper 01 October 1993 Pages: 575 - 592

6. Kinetics of combined drug action

   • Tamotsu Koizumi
   • Masawo Kakemi
   • Kazunori Katayama

   OriginalPaper 01 October 1993 Pages: 593 - 607

7. Two constrained deconvolution methods using spline functions

   • Davide Verotta

   OriginalPaper 01 October 1993 Pages: 609 - 636

8. Announcements

   Announcement 01 October 1993 Pages: 637 - 637