1. Preface: Chromosomal Instability and Breast Cancer Pathogenesis

   • Ashok R. Venkitaraman

   Editorial Introduction Pages: 217 - 220

2. The Genetic Epidemiology of Breast Cancer Genes

   • Deborah Thompson
   • Douglas Easton

   OriginalPaper Pages: 221 - 236

3. BRCA1 and BRCA2 in Breast Cancer Predisposition and Recombination Control

   • Ralph Scully
   • Anyong Xie

   OriginalPaper Pages: 237 - 246

4. ATM and Genome Maintenance: Defining Its Role in Breast Cancer Susceptibility

   • Kum Kum Khanna
   • Georgia Chenevix-Trench

   OriginalPaper Pages: 247 - 262

5. Genetic and Epigenetic Changes in Mammary Epithelial Cells May Mimic Early Events in Carcinogenesis

   • Thea D. Tlsty
   • Yongping G. Crawford
   • Mona L. Gauthier

   OriginalPaper Pages: 263 - 274

6. Centrosome Amplification and the Origin of Chromosomal Instability in Breast Cancer

   • Jeffrey L. Salisbury
   • Antonino B. D'Assoro
   • Wilma L. Lingle

   OriginalPaper Pages: 275 - 283

7. Telomere Shortening Occurs Early During Breast Tumorigenesis: A Cause of Chromosome Destabilization Underlying Malignant Transformation?

   • Alan K. Meeker
   • Pedram Argani

   OriginalPaper Pages: 285 - 296