1. Editorial

   • Suresh I.S. Rattan

   Editorial Introduction Pages: 1 - 1

2. Pre-meeting Abstracts

   Abstract List Pages: 1 - 15

3. Cellular coenzyme Q₁₀ redox poise constitutes a major cell metabolic and gene regulatory system

   • Anthony W. Linnane

   OriginalPaper Pages: 3 - 6

4. Meeting Abstracts

   Abstract List Pages: 17 - 126

5. A personal retrospective on the genetics of aging

   • Thomas E. Johnson

   OriginalPaper Pages: 7 - 12

6. Author index

   Authors Index Pages: 127 - 133

7. Stress-induced premature senescence: from biomarkers to likeliness of in vivo occurrence

   • Olivier Toussaint
   • José Remacle
   • Florence Chainiaux

   OriginalPaper Pages: 13 - 17

8. Reasons for the degeneration of ageing skeletal muscle: a central role for IGF-1 signalling

   • Miranda D. Grounds

   OriginalPaper Pages: 19 - 24

9. Age-related atrophy of rat soleus muscle is accompanied by changes in fibre type composition, bioenergy decline and mtDNA rearrangements

   • Natalia O. Yarovaya
   • Ludmilla Kramarova
   • Anthony W. Linnane

   OriginalPaper Pages: 25 - 27

10. Stochastic mitochondrial DNA changes: bioenergy decline in type I skeletal muscle fibres correlates with a decline in the amount of amplifiable full-length mtDNA

    • George Kopsidas
    • Chunfang Zhang
    • Anthony W. Linnane

    OriginalPaper Pages: 29 - 36

11. The effects of ageing on the response to cardiac surgery: protective strategies for the ageing myocardium

    • Franklin L. Rosenfeldt
    • Salvatore Pepe
    • William Lyon

    OriginalPaper Pages: 37 - 40

12. Interfibrillar cardiac mitochondrial comples III defects in the aging rat heart

    • Charles L. Hoppel
    • Shadi Moghaddas
    • Edward J. Lesnefsky

    OriginalPaper Pages: 41 - 44

13. Influence of ageing on the sympathetic nervous system and adrenal medulla at rest and during stress

    • Murray Esler
    • Gavin Lambert
    • Douglas R. Seals

    OriginalPaper Pages: 45 - 49

14. Excited to death: different ways to lose your neurones

    • Peter R. Dodd

    OriginalPaper Pages: 51 - 56

15. The SAMP8 mouse: a model of Alzheimer disease?

    • John E. Morley

    OriginalPaper Pages: 57 - 60

16. A model for a blinding eye disease of the aged

    • Dan Zhang
    • May C. Lai
    • P. Elizabeth Rakoczy

    OriginalPaper Pages: 61 - 66

17. The anorexia of ageing

    • Ian M. Chapman
    • Caroline G. MacIntosh
    • Michael Horowitz

    OriginalPaper Pages: 67 - 71

18. Vitamin D deficiency and aging: implications for general health and osteoporosis

    • Erik Fink Eriksen
    • Henning Glerup

    OriginalPaper Pages: 73 - 77

19. Mechanisms involved in bone resorption

    • Nobuyuki Udagawa

    OriginalPaper Pages: 79 - 83

20. Osteoarthritis, genetic and molecular mechanisms

    • Peter Ghosh
    • Margaret Smith

    OriginalPaper Pages: 85 - 88

21. Pathways defective in the human premature aging disease Werner syndrome

    • Vilhelm A. Bohr
    • Robert M. Brosh Jr.
    • Parimal Karmakar

    OriginalPaper Pages: 89 - 94

22. Induction of DNA damage by oxidised amino acids and proteins

    • Catherine Luxford
    • Roger T. Dean
    • Michael J. Davies

    OriginalPaper Pages: 95 - 102

23. How to re-energise old mitochondria without shooting yourself in the foot

    • Christopher Driver
    • Angela Georgiou

    OriginalPaper Pages: 103 - 106

24. Signaling on telomerase: a master switch in cell aging and immortalization

    • He Li
    • Jun-Ping Liu

    OriginalPaper Pages: 107 - 116

25. Hormetic action of mild heat stress decreases the inducibility of protein oxidation and glycoxidation in human fibroblasts

    • Philippe Verbeke
    • Marianne Deries
    • Suresh I.S. Rattan

    OriginalPaper Pages: 117 - 120

26. Protein degradation during aging: The lysosome-, the calpain- and the proteasome-dependent cellular proteolytic systems

    • Niki Chondrogianni
    • Emmanouil G. Fragoulis
    • Efstathios S. Gonos

    OriginalPaper Pages: 121 - 123

27. The bifunctional activity of ubiquinone in lysosomal membranes

    • Hans Nohl
    • Lars Gille

    OriginalPaper Pages: 125 - 131

28. The proteomics of ageing

    • Gary S. Cobon
    • Nicole Verrills
    • Anthony W. Linnane

    OriginalPaper Pages: 133 - 136

29. Effect of age on scramblase content in human platelets

    • J.M. Noble
    • T.H. Thomas
    • G.A. Ford

    OriginalPaper Pages: 137 - 137

30. Instructions for authors

    Instructions for Authors Pages: 139 - 141