Cellular coenzyme Q10 redox poise constitutes a major cell metabolic and gene regulatory system Anthony W. Linnane OriginalPaper Pages: 3 - 6
Stress-induced premature senescence: from biomarkers to likeliness of in vivo occurrence Olivier ToussaintJosé RemacleFlorence Chainiaux OriginalPaper Pages: 13 - 17
Reasons for the degeneration of ageing skeletal muscle: a central role for IGF-1 signalling Miranda D. Grounds OriginalPaper Pages: 19 - 24
Age-related atrophy of rat soleus muscle is accompanied by changes in fibre type composition, bioenergy decline and mtDNA rearrangements Natalia O. YarovayaLudmilla KramarovaAnthony W. Linnane OriginalPaper Pages: 25 - 27
Stochastic mitochondrial DNA changes: bioenergy decline in type I skeletal muscle fibres correlates with a decline in the amount of amplifiable full-length mtDNA George KopsidasChunfang ZhangAnthony W. Linnane OriginalPaper Pages: 29 - 36
The effects of ageing on the response to cardiac surgery: protective strategies for the ageing myocardium Franklin L. RosenfeldtSalvatore PepeWilliam Lyon OriginalPaper Pages: 37 - 40
Interfibrillar cardiac mitochondrial comples III defects in the aging rat heart Charles L. HoppelShadi MoghaddasEdward J. Lesnefsky OriginalPaper Pages: 41 - 44
Influence of ageing on the sympathetic nervous system and adrenal medulla at rest and during stress Murray EslerGavin LambertDouglas R. Seals OriginalPaper Pages: 45 - 49
A model for a blinding eye disease of the aged Dan ZhangMay C. LaiP. Elizabeth Rakoczy OriginalPaper Pages: 61 - 66
The anorexia of ageing Ian M. ChapmanCaroline G. MacIntoshMichael Horowitz OriginalPaper Pages: 67 - 71
Vitamin D deficiency and aging: implications for general health and osteoporosis Erik Fink EriksenHenning Glerup OriginalPaper Pages: 73 - 77
Osteoarthritis, genetic and molecular mechanisms Peter GhoshMargaret Smith OriginalPaper Pages: 85 - 88
Pathways defective in the human premature aging disease Werner syndrome Vilhelm A. BohrRobert M. Brosh Jr.Parimal Karmakar OriginalPaper Pages: 89 - 94
Induction of DNA damage by oxidised amino acids and proteins Catherine LuxfordRoger T. DeanMichael J. Davies OriginalPaper Pages: 95 - 102
How to re-energise old mitochondria without shooting yourself in the foot Christopher DriverAngela Georgiou OriginalPaper Pages: 103 - 106
Signaling on telomerase: a master switch in cell aging and immortalization He LiJun-Ping Liu OriginalPaper Pages: 107 - 116
Hormetic action of mild heat stress decreases the inducibility of protein oxidation and glycoxidation in human fibroblasts Philippe VerbekeMarianne DeriesSuresh I.S. Rattan OriginalPaper Pages: 117 - 120
Protein degradation during aging: The lysosome-, the calpain- and the proteasome-dependent cellular proteolytic systems Niki ChondrogianniEmmanouil G. FragoulisEfstathios S. Gonos OriginalPaper Pages: 121 - 123
The bifunctional activity of ubiquinone in lysosomal membranes Hans NohlLars Gille OriginalPaper Pages: 125 - 131
The proteomics of ageing Gary S. CobonNicole VerrillsAnthony W. Linnane OriginalPaper Pages: 133 - 136
Effect of age on scramblase content in human platelets J.M. NobleT.H. ThomasG.A. Ford OriginalPaper Pages: 137 - 137