Restricting the level of the proteins essential for the regulation of the initiation step of replication extends the chronological lifespan and reproductive potential in budding yeast Karolina StępieńTuguldur EnkhbaatarMateusz Mołoń Research Article Open access 06 June 2024
Enhancing the human health and lifespan: a targeted strategy emphasizing statins Edward CalabresePeter Pressman Perspective 29 May 2024
Compensation effect of mortality is a challenge to substantial lifespan extension of humans Natalia S. GavrilovaLeonid A. Gavrilov Research Article 29 May 2024
Intracellular cytokines in peritoneal leukocytes relate to lifespan in aging and long-lived female mice Irene Martínez de TodaJudith FélixMónica De la Fuente Research Article Open access 15 May 2024
Inhibition of mTOR prevents glucotoxicity-mediated increase of SA-beta-gal, p16INK4a, and insulin hypersecretion, without restoring electrical features of mouse pancreatic islets Tereso J. GuzmánNina KlöpperMartina Düfer Research Article Open access 15 May 2024
Correction: Quercetin and dasatinib, two powerful senolytics in age-related cardiovascular disease Mario NietoMina KonigsbergAlejandro Silva-Palacios Correction 11 May 2024
Analysis of the relationship between age-related erythrocyte dysfunction and fatigue Yuichiro OgataTakaaki YamadaSeiji Hasegawa Research Article 07 May 2024
Correction: Empaglifozin improves kidney senescence induced by d-galactose by reducing sirt1-mediated oxidative stress Ronghua FangJie ChenDongfang Liu Correction 26 April 2024
Combined dasatinib and quercetin treatment contributes to skin rejuvenation through selective elimination of senescent cells in vitro and in vivo Kento TakayaKazuo Kishi Research Article 15 April 2024
RNA-sequencing exploration on SIR2 and SOD genes in Polyalthia longifolia leaf methanolic extracts (PLME) mediated anti-aging effects in Saccharomyces cerevisiae BY611 yeast cells Manisekaran HemagirriYeng ChenSreenivasan Sasidharan Research Article 15 April 2024
Altered lactate/pyruvate ratio may be responsible for aging-associated intestinal barrier dysfunction in male rats Berrin PapilaAyla KarimovaIlhan Onaran Research Article Open access 15 April 2024
Resveratrol activates autophagy and protects from UVA-induced photoaging in human skin fibroblasts and the skin of male mice by regulating the AMPK pathway Yangmin XiaHao ZhangQian Tan Research Article Open access 09 April 2024
Telomeres and aging: on and off the planet! Christopher E. MasonMaria A. SierraSusan M. Bailey Research Article Open access 06 April 2024 Pages: 313 - 327
Chronic trans fatty acid consumption shortens lifespan in male Drosophila melanogaster on a high-sugar and high-fat diet Qianhua YuanMengliu LuoHonghui Guo Research Article 06 April 2024
Piperine improves the health span of Drosophila melanogaster with age- and sex-specific effect Hye-Yeon LeeJi-Hyeon LeeKyung-Jin Min Research Article 28 March 2024
The potential use of nanozyme in aging and age‐related diseases Amirsasan GorgzadehParia Arab AmiriKhairia abdulrahman abdulallah Review ARticle 11 March 2024
Telomeres in health and longevity: special issue in memory of Alexey Olovnikov Ivan A. Olovnikov Editorial 05 March 2024 Pages: 191 - 193
A comprehensive model for the biochemistry of ageing, senescence and longevity Hiskias Gerrit KeizerR. BrandsWillem Seinen Review Article 05 March 2024
Regulation of ENPP5, a senescence-associated secretory phenotype factor, prevents skin aging Kento TakayaKazuo Kishi Research Article 04 March 2024 Pages: 529 - 542
The SGLT2 inhibitor empagliflozin inhibits skeletal muscle fibrosis in naturally aging male mice through the AMPKα/MMP9/TGF-β1/Smad pathway Qixuan HuangJie ChenDongfang Liu Research Article 26 February 2024 Pages: 567 - 581
Cell-type specific and differential expression of LINC-RSAS long noncoding RNA declines in the testes during ageing of the rat Ajay Kumar DangaSukhleen KourPramod C. Rath Research Article 14 February 2024 Pages: 543 - 566
Renal aging and mitochondrial quality control Xiuli GuoJiao WangLi Xu Review Article 13 February 2024 Pages: 399 - 414
A CRISPR base editing approach for the functional assessment of telomere biology disorder-related genes in human health and aging Gustavo BorgesYahya BenslimaneLea Harrington Research Article Open access 04 February 2024 Pages: 361 - 378
Linking telomere dynamics to evolution, life history and environmental change: perspectives, predictions and problems Pat Monaghan Review Article Open access 22 January 2024 Pages: 301 - 311
Sustained exposure to high glucose induces differential expression of cellular senescence markers in murine macrophages but impairs immunosurveillance response to senescent cells secretome Bhawna DiwanRahul YadavRohit Sharma Research Article 19 January 2024
Seven knowledge gaps in modern biogerontology Suresh I. S. Rattan Editorial 11 January 2024 Pages: 1 - 8
Age and dietary restriction modulate mitochondrial quality in quadriceps femoris muscle of male mice Ting-Rui ZhangChun-Hsien ChiangChing-Yi Chen Research Article 06 January 2024 Pages: 447 - 459
Telomeres, cellular senescence, and aging: past and future Madeline EppardJoão F. PassosStella Victorelli Review Article 27 December 2023 Pages: 329 - 339
Berberis vulgaris L. extract supplementation exerts regulatory effects on the lifespan and healthspan of Drosophila through its antioxidant activity depending on the sex Denis GolubevElena PlatonovaAlexey Moskalev Research Article 27 December 2023 Pages: 507 - 528
Gut microbiota influence frailty syndrome in older adults: mechanisms and therapeutic strategies Xiao-Ming WangLu FanShi-Chao Lv Review Article 27 December 2023 Pages: 107 - 129
Telomere length and cancer risk: finding Goldilocks Sharon A. Savage Review Article 18 December 2023 Pages: 265 - 278
Application potential of senolytics in clinical treatment Tiantian LiShiyuan LiJinming Kong Review Article 18 December 2023 Pages: 379 - 398
How soon do metabolic alterations and oxidative distress precede the reduction of muscle mass and strength in Wistar rats in aging process? Malu Cristina de Araújo Montoro LimaMatheus Felipe ZazulaKatya Naliwaiko Research Article 08 December 2023 Pages: 491 - 506
An underappreciated peculiarity of late-life human mortality kinetics assessed through the lens of a generalization of the Gompertz-Makeham law A. Golubev Research Article 25 November 2023 Pages: 479 - 490
Telomere shortening induces aging-associated phenotypes in hiPSC-derived neurons and astrocytes Jasmine HarleyMunirah Mohamad SantosaShi-Yan Ng Research Article Open access 21 November 2023 Pages: 341 - 360
Targeting the epigenetically older individuals for geroprotective trials: the use of DNA methylation clocks Elena SandalovaAndrea B. Maier Perspective 16 November 2023 Pages: 423 - 431
Chromosome ends and the theory of marginotomy: implications for reproduction Isabel Córdova-OrizAlba M. PolonioElisa Varela Review article 09 November 2023 Pages: 227 - 248
T-cell lymphocytes’ aging clock: telomeres, telomerase and aging Alain CheblyCharbel KhalilEdith Chevret Review Article 02 November 2023 Pages: 279 - 288
AMPK signaling inhibits the differentiation of myofibroblasts: impact on age-related tissue fibrosis and degeneration Antero Salminen Review Article Open access 02 November 2023 Pages: 83 - 106
Methods that shaped telomerase research Louise BartleRaymund J. Wellinger Review Article Open access 31 October 2023 Pages: 249 - 263
“Slight chemical damage due to drinking modest amount of sake, might induce beneficial effects” as a form of hormesis: an interview with Professor Sataro Goto Zsolt Radak INTERVIEW Open access 26 October 2023 Pages: 415 - 422
Interaction effect of mutations in the genes (piwi and aub) of the Argonaute family and hobo transposons on the integral survival parameters of Drosophila melanogaster Elena Yushkova Research Article 21 October 2023 Pages: 131 - 146
Mitochondria and telomeres: hand in glove Mélina VaursElif Beyza DoluAnabelle Decottignies Review Article 21 October 2023 Pages: 289 - 300
The influence of biological sex in human skeletal muscle transcriptome during ageing Xiaoyu HuangMao ChenLi Hong Research Article 04 October 2023 Pages: 461 - 478
Quercetin and dasatinib, two powerful senolytics in age-related cardiovascular disease Mario NietoMina KonigsbergAlejandro Silva-Palacios Review article 25 September 2023 Pages: 71 - 82
Fisetin, a potential skin rejuvenation drug that eliminates senescent cells in the dermis Kento TakayaToru AsouKazuo Kishi Research Article 22 September 2023 Pages: 161 - 175
Heat-induced hormesis in longevity is linked to heat-stress sensitivity across laboratory populations from diverse altitude of origin in Drosophila buzzatii Mariano AlmirónFederico H. GomezFabian M. Norry Research Article 19 September 2023 Pages: 183 - 190
Aging adipose tissue, insulin resistance, and type 2 diabetes Yixuan ZhaoRensong Yue Review Article 19 September 2023 Pages: 53 - 69
Plasma proteins as potential biomarkers of aging of single tissue and cell type Daigo Okada Research Article 14 September 2023 Pages: 177 - 181