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Bioactive injectables based on calcium phosphates for hard tissues: A recent update

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Tissue Engineering and Regenerative Medicine Aims and scope

Abstract

Self-gelling/setting injectable biomaterials hold great promise for the delivery of bioactive molecules and cells useful for tissue engineering and regenerative medicine. In the biopolymeric regime, a broad compositional spectrum has been developed, yet very limited compositional options have been developed for inorganic injectables. For example, calcium phosphate (CaP)-based injectables are considered to be one of the most promising classes of materials for bone repair and reconstruction. Here we present an update on the recent advancements in CaP-injectables, where significant efforts have been undertaken to improve the regenerative capacity by tailoring the chemical compositions and increasing the drug delivery potential.

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Authors and Affiliations

  1. Department of Nanobiomedical Science & BK21 PLUS NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan, Korea

    Roman A. Perez, Song-Hee Shin, Cheol-Min Han & Hae-Won Kim

  2. Institute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, Korea

    Roman A. Perez, Song-Hee Shin & Hae-Won Kim

  3. Department of Biomaterials Science, Dankook University Dental College, Cheonan, Korea

    Cheol-Min Han & Hae-Won Kim

  4. Department of Nanobiomedical Science & BK21 PLUS NBM Global Research Center for Regenerative Medicine, Dankook University, 119 Dandaero, Dongnam-gu, Cheonan, 330-714, Korea

    Hae-Won Kim

Authors
  1. Roman A. Perez
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  2. Song-Hee Shin
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  3. Cheol-Min Han
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  4. Hae-Won Kim
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Corresponding author

Correspondence to Hae-Won Kim.

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Perez, R.A., Shin, SH., Han, CM. et al. Bioactive injectables based on calcium phosphates for hard tissues: A recent update. Tissue Eng Regen Med 12, 143–153 (2015). https://doi.org/10.1007/s13770-015-0096-1

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  • DOI: https://doi.org/10.1007/s13770-015-0096-1

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