Skip to main content
SpringerLink
Log in

Green fabrication of nanocomposite doped with selenium nanoparticle–based starch and glycogen with its therapeutic activity: antimicrobial, antioxidant, and anti-inflammatory in vitro

  • Original Article
  • Published:
Biomass Conversion and Biorefinery Aims and scope Submit manuscript

A Correction to this article was published on 17 September 2022

This article has been updated

Abstract

Synthesis of nanoparticles (NPs) was market strictly attention in the materials and their applications where offered multifunction materials. The synthesis process of NPs takes a wide range of methodology. Nowadays, the green synthesis methods are the pioneer as well as acceptable towered the environment. In this present work, the green nanocomposites were prepared using an ecofriendly method. Additionally, the prepared nanocomposite was loaded with selenium nanoparticles (SeNPs) using the green process as well. The produced nanocomposites were characterized using UV–visible, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy, X-ray diffraction (XRD), scan electron microscope (SEM), energy-dispersive X-ray analyses (EDX), transmission electron microscope (TEM), and dynamic light scattering (DLS). The prepared nanocomposite recorded the nanostructure around 90 nm, and the selenium loaded nanocomposite 78 nm. The loaded nanocomposite (LNC) with SeNPs displayed good antioxidant activity using 2,2-diphenyl-1- picrylhydrazyl (DPPH) radical scavenging test with IC50 68 µg/mL compared with free nanocomposite (FNC) IC50 (239.1 µg/mL). Anti-inflammatory potential represented by hemolysis inhibition % was promoted by LNC with SeNPs (31.7% and 69.1% at 100 and 1000 µg/mL, respectively) compared to hemolysis inhibition 20.6 and 64.2% at 100 and 1000 µg/mL of FNC, respectively. B. subtilis, S. aureus, E. faecalis, P. vulgaris, P. aeruginosa, E. coli, S. typhimurium, and C. albicans were more affected by LNC than FNC with increasing fold 16.55, 26.75, 30.60, 41.81, 53.10, 40.77, 10.98, and 41.10%, respectively. Unfortunately, neither FNC nor LNC showed any activity against black mould M. circinelloide and mycotoxogenic fungi A. niger and A. flavus. From the current findings, LNC with SeNPs exhibited highest in vitro therapeutic potential than FNC.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

Data availability

All data that support the findings of this study are available within the article.

Change history

References

  1. Kazi AA, Pradyot KR, Chowdhury MH, Dishari D, Riddhi V, Manas RB (2021) Chapter 2 Starch-based nanomaterials in drug delivery applications Editor(s): Hriday Bera Chowdhury Mobaswar Hossain Sudipta Saha Biopolymer-based nanomaterials in drug delivery and biomedical applications. Academic Press 2021:31–56

    Google Scholar 

  2. Steven B, Colleoni C, Cenci U, Raj JN, Tirtiaux C (2011) The evolution of glycogen and starch metabolism in eukaryotes gives molecular clues to understand the establishment of plastid endosymbiosis. J Exp Bot 62(6):1775–1801. https://doi.org/10.1093/jxb/erq411

    Article  Google Scholar 

  3. Sharaf OM, Al-Gamal MS, Ibrahim GA, Dabiza NM, Salem SS, El-ssayad MF, Youssef AM (2019) Evaluation and characterization of some protective culture metabolites in free and nano-chitosan-loaded forms against common contaminants of Egyptian cheese. Carbohydr Polym 223:115094

    Article  Google Scholar 

  4. Al-Rajhi AMH, Yahya R, Bakri MMY, R. & T. M. Abdelghany TM. (2022) In situ green synthesis of Cu-doped ZnO based polymers nanocomposite with studying antimicrobial, antioxidant and anti-inflammatory activities. Appl Biol Chem 65:35. https://doi.org/10.1186/s13765-022-00702-0

    Article  Google Scholar 

  5. Yahya R, Al-Rajhi AMH, Alzaid SZ, Al Abboud MA, Almuhayawi MS, Al Jaouni SK, Selim S, Ismail KS, Abdelghany TM (2022) Molecular docking and efficacy of Aloe vera gel based on chitosan nanoparticles against Helicobacter pylori and its antioxidant and anti-inflammatory activities. Polymers (Basel) 14(15):2994. https://doi.org/10.3390/polym14152994

    Article  Google Scholar 

  6. Salem SS, Fouda A (2021) Green synthesis of metallic nanoparticles and their prospective biotechnological applications: an overview. Biol Trace Elem Res 199:344–370

    Article  Google Scholar 

  7. Hashem AH, Shehabeldine AM, Ali OM, Salem SS (2022) Synthesis of chitosan-based gold nanoparticles: antimicrobial and wound-healing activities. Polymers 14:2293

    Article  Google Scholar 

  8. Shehabeldine AM, Salem SS, Ali OM, Abd-Elsalam KA, Elkady FM, Hashem AH (2022) Multifunctional silver nanoparticles based on chitosan: antibacterial, antibiofilm, antifungal, antioxidant, and wound-healing activities. J Fungi 8:612

    Article  Google Scholar 

  9. Abu-Elghait M, Hasanin M, Hashem AH, Salem SS (2021) Ecofriendly novel synthesis of tertiary composite based on cellulose and myco-synthesized selenium nanoparticles: Characterization, antibiofilm and biocompatibility. Int J Biol Macromol 175:294–303

    Article  Google Scholar 

  10. Hashem AH, Khalil AMA, Reyad AM, Salem SS (2021) Biomedical applications of mycosynthesized selenium nanoparticles using Penicillium expansum ATTC 36200. Biol Trace Elem Res 199:3998–4008

    Article  Google Scholar 

  11. Wojnilowicz M, Besford QA, Wu YL, Loh XJ, Braunger JA, Glab A, Cortez-Jugo C, Caruso F, Cavalieri F (2018 Sep) Glycogen-nucleic acid constructs for gene silencing in multicellular tumor spheroids. Biomater 176:34–49. https://doi.org/10.1016/j.biomaterials.2018.05.024

    Article  Google Scholar 

  12. Gálisová A, Jirátová M, Rabyk M, Sticová E, Hájek M, Hrubý M, Jirák D (2020) Glycogen as an advantageous polymer carrier in cancer theranostics: straightforward in vivo evidence. Sci Rep 10(1):10411. https://doi.org/10.1038/s41598-020-67277-y

    Article  Google Scholar 

  13. Xie L, Shen M, Hong Y, Ye H, Huang L, Xie J (2020) Chemical Modifications of Polysaccharides and Their Anti-Tumor Activities. Carbohydr Polym 229:115436

    Article  Google Scholar 

  14. Shoeibi S, Mashreghi M (2017) Biosynthesis of selenium nanoparticles using Enterococcus faecalis and evaluation of their antibacterial activities. J Trace Elem Med Biol 39:135–139. https://doi.org/10.1016/j.jtemb.2016.09.003

    Article  Google Scholar 

  15. Li J, Shen B, Nie S, Duan Z, Chen K (2019) A Combination of selenium and polysaccharides: promising therapeutic potential. Carbohydr Polym 206:163–173

    Article  Google Scholar 

  16. Wu X, Yao J, Yang Z, Yue W, Ren Y, Zhang C, Liu X, Wang H, Zhao X, Yuan S et al (2011) Improved fetal hair follicle development by maternal supplement of selenium at nano size (nano-Se). Livest Sci 142:270–275

    Article  Google Scholar 

  17. Ramya S, Shanmugasundaram T, Balagurunathan R (2015) Biomedical potential of actinobacterially synthesized selenium nanoparticles with special reference to anti-biofilm, anti-oxidant, wound healing, cytotoxic and anti-viral activities. J Trace Elem Med Biol Organ Soc Miner Trace Elem GMS 32:30–39

    Article  Google Scholar 

  18. Stevanovi´c M, Filipovi´c N, Djurdjevi´c J, Luki´c M, Milenkovi´c M, Boccaccini A (2015) 45S5Bioglass®-based scaffolds coated with selenium nanoparticles or with poly(lactide-co-glycolide)/selenium particles: processing, evaluation and antibacterial activity. Colloids Surf B Biointerfaces 132:208–215

    Article  Google Scholar 

  19. Ikram M, Javed B, Raja NI, Mashwani ZU (2021) Biomedical potential of plant-based selenium nanoparticles: a comprehensive review on therapeutic and mechanistic aspects. Int J Nanomed 16:249–268. https://doi.org/10.2147/IJN.S295053

    Article  Google Scholar 

  20. Salem SS, Hammad EN, Mohamed AA, El-Dougdoug W (2023) A comprehensive review of nanomaterials: types, synthesis, characterization, and applications. Biointerface Res Appl Chem 2022:13

    Google Scholar 

  21. Hatami R, Javadi A, Jafarizadeh-Malmiri H (2020) Effectiveness of six different methods in green synthesis of selenium nanoparticles using propolis extract: Screening and characterization. Green Process Synth 9(1):685–692. https://doi.org/10.1515/gps-2020-0065

    Article  Google Scholar 

  22. Begum SJP, Pratibha S, Rawat JM, Venugopal D, Sahu P, Gowda A, Qureshi KA, Jaremko M (2022) Recent advances in green synthesis, characterization, and applications of bioactive metallic nanoparticles. Pharmaceuticals 15:455. https://doi.org/10.3390/ph15040455

    Article  Google Scholar 

  23. Siddiqi KS, Husen A (2017) Recent advances in plant-mediated engineered gold nanoparticles and their application in biological system. J Trace Elem Med Biol 40:10–23. https://doi.org/10.1016/j.jtemb.2016.11.012

    Article  Google Scholar 

  24. Zambonino MC, Quizhpe EM, Jaramillo FE, Rahman A, Santiago Vispo N, Jeffryes C, Dahoumane SA (2021) Green synthesis of selenium and tellurium nanoparticles: current trends, biological properties and biomedical applications. Int J Mol Sci 22:989. https://doi.org/10.3390/ijms22030989

    Article  Google Scholar 

  25. Zohra E, Ikram M, Omar AA, Hussain M, Satti SH, Raja NI, Mashwani Z, Ehsan M (2021) Potential applications of biogenic selenium nanoparticles in alleviating biotic and abiotic stresses in plants: a comprehensive insight on the mechanistic approach and future perspectives. Green Process Synth 10(1):456–475. https://doi.org/10.1515/gps-2021-0047

    Article  Google Scholar 

  26. Ali K, Dwivedi S, Azam A, Saquib Q, Al-Said MS, Al-Khedhairy A, Musarrat J (2016) Aloe vera extract functionalized zinc oxide nanoparticles as nanoantibiotics against multi-drug resistant clinical bacterial isolates. J Colloid Interface Sci 472:145–156. https://doi.org/10.1016/j.jcis.2016.03.021

    Article  Google Scholar 

  27. Wadhwani SA, Gorain M, Banerjee P, Shedbalkar UU, Singh R, Kundu GC, Chopade BA (2017) Green synthesis of selenium nanoparticles using Acinetobacter sp SW30: optimization, characterization and its anticancer activity in breast cancer cells. Int J Nanomedicine 12:6841–6855. https://doi.org/10.2147/IJN.S139212

    Article  Google Scholar 

  28. Pandey S, Awasthee N, Shekher A, Rai LC, Gupta SC, Dubey SK (2021 Dec) Biogenic synthesis and characterization of selenium nanoparticles and their applications with special reference to antibacterial, antioxidant, anticancer and photocatalytic activity. Bioprocess Biosyst Eng 44(12):2679–2696. https://doi.org/10.1007/s00449-021-02637-0

    Article  Google Scholar 

  29. Rajkumar K, Mvs S, Koganti S, Burgula S (2020) Selenium nanoparticles synthesized using Pseudomonas stutzeri (MH191156) show antiproliferative and anti-angiogenic activity against cervical cancer cells. Int J Nanomedicine 15:4523–4540. https://doi.org/10.2147/IJN.S247426

    Article  Google Scholar 

  30. Shakibaie M, Khorramizadeh MR, Faramarzi MA, Sabzevari O, Shahverdi AR (2010) Biosynthesis and recovery of selenium nanoparticles and the effects on matrix metalloproteinase 2 expression. Biotechnol Appl Biochem 56:7–15. https://doi.org/10.1042/BA20100042

    Article  Google Scholar 

  31. Salem SS (2022) Bio-fabrication of selenium nanoparticles using Baker’s yeast extract and its antimicrobial efficacy on food borne pathogens. Appl Biochem Biotechnol 194:1898–1910

    Article  Google Scholar 

  32. Hashem AH, Selim TA, Alruhaili MH, Selim S, Al khalifah DHM, AlJaouni SK, Salem SS (2022) Unveiling antimicrobial and insecticidal activities of biosynthesized selenium nanoparticles using prickly pear peel waste. J Funct Biomater 13:112. https://doi.org/10.3390/jfb13030112

    Article  Google Scholar 

  33. Gunti L, Dass RS, Kalagatur NK (2019 Apr) Phytofabrication of selenium nanoparticles from Emblica officinalis fruit extract and exploring its biopotential applications: antioxidant, antimicrobial, and biocompatibility. Front Microbiol 30(10):931. https://doi.org/10.3389/fmicb.2019.00931

    Article  Google Scholar 

  34. Hernández-Díaz JA, Garza-García JJ, León-Morales JM, Zamudio-Ojeda A, Arratia-Quijada J, Velázquez-Juárez G, López-Velázquez JC, García-Morales S (2021) Antibacterial activity of biosynthesized selenium nanoparticles using extracts of Calendula officinalis against potentially clinical bacterial strains. Molecules 26(19):5929. https://doi.org/10.3390/molecules26195929

    Article  Google Scholar 

  35. Ullah A, Yin X, Wang F, Xu B, Mirani ZA, Xu B, Chan MWH, Ali A, Usman M, Ali N, Naveed M (2021) Biosynthesis of selenium nanoparticles (via Bacillus subtilis BSN313), and their isolation, characterization, and bioactivities. Molecules 26(18):5559. https://doi.org/10.3390/molecules26185559

    Article  Google Scholar 

  36. Ho CT, Nguyen T-H, Lam T-T, Le D-Q, Nguyen CX, Leee J-H, Hur H-G (2021) Biogenic synthesis of selenium nanoparticles by Shewanella sp HN-41 using a modified bioelectrochemical system. Electron J Biotechnol 2021:54. https://doi.org/10.1016/j.ejbt.2021.07.004

    Article  Google Scholar 

  37. Shoeibi S, Mashreghi M (2017 Jan) Biosynthesis of selenium nanoparticles using Enterococcus faecalis and evaluation of their antibacterial activities. J Trace Elem Med Biol 39:135–139. https://doi.org/10.1016/j.jtemb.2016.09.003

    Article  Google Scholar 

  38. Salem SS, Husen A (2022) Chapter 14-Effect of engineered nanomaterials on soil microbiomes and their association with crop growth and production. In: Husen A (ed) Engineered Nanomaterials for Sustainable Agricultural Production, Soil Improvement and Stress Management. Academic Press, Cambridge, MA, USA, pp 311–336

    Google Scholar 

  39. Lashin I, Hasanin M, Hassan SAM et al (2021) Green biosynthesis of zinc and selenium oxide nanoparticles using callus extract of Ziziphus spina-christi: characterization, antimicrobial, and antioxidant activity. Biomass Conv Bioref. https://doi.org/10.1007/s13399-021-01873-4

    Article  Google Scholar 

  40. Maruthapandi M, Saravanan A, Gupta A, Luong JHT, Gedanken A (2022) Antimicrobial activities of conducting polymers and their composites. Macromol 2:78–99. https://doi.org/10.3390/macromol2010005

    Article  Google Scholar 

  41. Abdelghany TM, Reham Y, Bakri MM, Ganash M, Basma H, Amin, Qanash H (2021) Effect of Thevetia peruviana seeds extract for microbial pathogens and cancer control. Int J Pharmacol 17(8):643–655. https://doi.org/10.3923/ijp.2021.643.655

    Article  Google Scholar 

  42. Meziti H, Bouriche H, Kada S, Demirtas I, Kizil M, Senator A, Garrido G (2019) Phytochemical analysis, and antioxidant, anti-hemolytic and genoprotective effects of Quercus ilex L. and Pinus halepensis Mill. methanolic extracts. J Pharm Pharmacogn Res 7:260–272

    Google Scholar 

  43. Salem SS, Badawy MSEM, Al-Askar AA, Arishi AA, Elkady FM, Hashem AH (2022) Green biosynthesis of selenium nanoparticles using orange peel waste: characterization, antibacterial and antibiofilm activities against multidrug-resistant bacteria. Life 12:893

    Article  Google Scholar 

  44. Alghunaim NS (2020) Characterization of selenium oxide nanofiller effect on the spectroscopic and thermal properties of Cs/PAM nanocomposites. J Market Res 9(3):3502–3510

    Google Scholar 

  45. Hasanin MS (2021) Simple, economic, ecofriendly method to extract starch nanoparticles from potato peel waste for biological applications. Starch – Stärke 73(9–10). https://doi.org/10.1002/star.202100055

  46. Shehabeldine A, El-Hamshary H, Hasanin M, El-Faham A, Al-Sahly M (2021) Enhancing the antifungal activity of Griseofulvin by incorporation a green biopolymer-based nanocomposite. Polymers 13:542. https://doi.org/10.3390/polym13040542

  47. Hasanin M, El-Henawy A, Eisa WH, El-Saied H, Sameeh M (2019) Nano-amino acid cellulose derivatives: eco-synthesis, characterization, and antimicrobial properties. Int J Biol Macromol 132:963–969. https://doi.org/10.1016/j.ijbiomac.2019.04.024

    Article  Google Scholar 

  48. Fernando I, Sanjeewa KKA, Samarakoon W, Lee WW, Kim H-S, Kim E-A, De Silva E (2017) FTIR characterization and antioxidant activity of water soluble crude polysaccharides of Sri Lankan marine algae. Algae 32(1):75–86. https://doi.org/10.4490/algae.2017.32.12.1

    Article  Google Scholar 

  49. Wang M, Qian R, Bao M, Gu C, Zhu P (2018) Raman, FT-IR and XRD study of bovine bone mineral and carbonated apatites with different carbonate levels. Mater Lett 210:203–206

    Article  Google Scholar 

  50. Izawa H, Nawaji M, Kaneko Y, Kadokawa J (2009) Preparation of glycogen-based polysaccharide materials by phosphorylase-catalyzed chain elongation of glycogen. Macromol Biosci 9(11):1098–1104. https://doi.org/10.1002/mabi.200900106

    Article  Google Scholar 

  51. Božanić DK, Dimitrijević-Branković S, Bibić N, Luyt AS, Djoković V (2011) Silver nanoparticles encapsulated in glycogen biopolymer: morphology, optical and antimicrobial properties. Carbohydr Polym 83(2):883–890. https://doi.org/10.1016/j.carbpol.2010.08.070

    Article  Google Scholar 

  52. Ingole AR, Thakare SR, Khati NT, Wankhade AV, Burghate DK (2010) Green synthesis of selenium nanoparticles under ambient condition. Chalcogenide Lett 7(7):485–489

    Google Scholar 

  53. Hashem AH, Salem SS (2022) Green and ecofriendly biosynthesis of selenium nanoparticles using Urtica dioica (stinging nettle) leaf extract: Antimicrobial and anticancer activity. Biotechnol J 17:2100432

    Article  Google Scholar 

  54. El-Badri AM, Batool M, Wang C, Hashem AM, Tabl KM, Nishawy E, Wang B (2021) Selenium and zinc oxide nanoparticles modulate the molecular and morpho-physiological processes during seed germination of Brassica napus under salt stress. Ecotoxicol Environ Saf 225:112695

    Article  Google Scholar 

  55. Forootanfar H, Adeli-Sardou M, Nikkhoo M, Mehrabani M, Amir-Heidari B, Shahverdi AR, Shakibaie M (2014) Antioxidant and cytotoxic effect of biologically synthesized selenium nanoparticles in comparison to selenium dioxide. J Trace Elem Med Biol 28(1):75–79

    Article  Google Scholar 

  56. Salem SS, Fouda MMG, Fouda A, Awad MA, Al-Olayan EM, Allam AA, Shaheen TI (2021) Antibacterial, cytotoxicity and larvicidal activity of green synthesized selenium nanoparticles using Penicillium corylophilum. J Clust Sci 32:351–361

    Article  Google Scholar 

  57. Ibrahim S, El Saied H, Hasanin M (2019) Active paper packaging material based on antimicrobial conjugated nano-polymer/amino acid as edible coating. J King Saud Univ Sci 31(4):1095–1102

    Article  Google Scholar 

  58. Papadaki D, Mhlongo GH, Motaung DE, Nkosi SS, Panagiotaki K, Christaki E, Assimakopoulos MN, Papadimitriou VC, Rosei F, Kiriakidis G, Ray SS (2019) Hierarchically porous Cu-, Co-, and Mn-doped platelet-like ZnO nanostructures and their photocatalytic performance for indoor air quality control. ACS Omega 4(15):16429–16440. https://doi.org/10.1021/acsomega.9b02016

    Article  Google Scholar 

  59. Pon MP, Jenit Sharmila G, Murugan C (2022) Green synthesis of selenium nanoparticles using Delonix regia and Nerium oleander flower extract and evaluation of their antioxidant and antibacterial activities. Inorg Nano-Met Chem. https://doi.org/10.1080/24701556.2021.2025099

    Article  Google Scholar 

  60. Menazea AA, Ismail AM, Nasser S, Awwad HA, Ibrahium, (2020) Physical characterization and antibacterial activity of PVA/Chitosan matrix doped by selenium nanoparticles prepared via one-pot laser ablation route. J Market Res 9(5):9598–9606. https://doi.org/10.1016/j.jmrt.2020.06.077

    Article  Google Scholar 

  61. Francis T, Rajeshkumar S, Roy A, Lakshmi T (2020) Anti-inflammatory and cytotoxic effect of arrow root mediated selenium nanoparticles. Pharmacogn J 12(6):1363–1367. https://doi.org/10.5530/pj.2020.12.188

    Article  Google Scholar 

  62. Xu C, Qiao L, Ma L, Yan S, Guo Y, Dou X, Zhang B, Roman A (2019 Jul) Biosynthesis of polysaccharides-capped selenium nanoparticles using Lactococcus lactis NZ9000 and their antioxidant and anti-inflammatory activities. Front Microbiol 26(10):1632. https://doi.org/10.3389/fmicb.2019.01632

    Article  Google Scholar 

Download references

Acknowledgements

All authors thanks Princess Nourah bint Abdulrahman University for their grant through Researchers Supporting Project number PNURSP2022R217, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.

Funding

All authors received financial support from the Princess Nourah bint Abdulrahman University through Researchers Supporting Project number PNURSP2022R217, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.

Author information

Authors and Affiliations

  1. Botany and Microbiology Department, Faculty of Science, Al-Azhar University, Cairo, 11725, Egypt

    Tarek M. Abdelghany

  2. Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh, 11671, Saudi Arabia

    Aisha M. H. Al-Rajhi

  3. Department of Medical Microbiology and Parasitology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia

    Mohammed S. Almuhayawi

  4. Yousef Abdullatif Jameel Scientific Chair of Prophetic Medicine Application, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia

    Mohammed S. Almuhayawi

  5. Biology Department, Faculty of Science, Jazan University, Jazan, Saudi Arabia

    Emad Abada, Mohamed A. Al Abboud & Hanan Moawad

  6. Plant Department, Faculty of Science, Fayoum University, Faiyum, Egypt

    Hanan Moawad

  7. Medical Microbiology, College of Science and Health Professions, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia

    Reham Yahya

  8. King Abduallah International Medical Research Center, Riyadh, Saudi Arabia

    Reham Yahya

  9. Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka, 72388, Saudi Arabia

    Samy Selim

Authors
  1. Tarek M. Abdelghany
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Aisha M. H. Al-Rajhi
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Mohammed S. Almuhayawi
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Emad Abada
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Mohamed A. Al Abboud
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Hanan Moawad
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Reham Yahya
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Samy Selim
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

Abdelghany T. M. and Aisha M. H. Al-Rajhi conceptualized the study and edited the manuscript; Mohammed S. Almuhayawi and Emad Abada performed the study methods and wrote the paper; Samy Selim and Mohamed A. Al Abboud designed the manuscript, prepared the original draft, and edited the manuscript; Hanan Moawad and Reham Yahya wrote the paper and performed some experiments; Samy Selim wrote the paper and final draft preparation.

Corresponding authors

Correspondence to Tarek M. Abdelghany or Samy Selim.

Ethics declarations

Competing interests

The authors declare no competing interests.

Ethical approval

Non applicable.

Additional information

Publisher's note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

The original online version of this article was revised: In this article, the author name Emad Abada was incorrectly written as Emad Abda.

Rights and permissions

Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Abdelghany, T.M., Al-Rajhi, A.M.H., Almuhayawi, M.S. et al. Green fabrication of nanocomposite doped with selenium nanoparticle–based starch and glycogen with its therapeutic activity: antimicrobial, antioxidant, and anti-inflammatory in vitro. Biomass Conv. Bioref. 13, 431–443 (2023). https://doi.org/10.1007/s13399-022-03257-8

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13399-022-03257-8

Keywords

Search

Navigation