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Synthesis and characterization of electrospun PU/PCL hybrid scaffolds

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Abstract

Polyurethane/poly(ɛ-caprolactone) (PU/PCL) scaffolds with various concentrations of PCL (0 to 40 wt%) were electrospun to evaluate the mechanical properties and the biocompatibility of the PU/PCL hybrid scaffolds. The 10 wt% PU/PCL scaffolds were chosen due to the absence of beads. The ultimate tensile strengths of 10 wt% PU and 15% PCL scaffolds were 8.0±1.3 MPa and 6.8±1.0 MPa. The tensile strength of PU/PCL scaffolds increased dramatically to 12.1±1.4 MPa when 10% PCL was added to PU. As the PCL content was raised to 20%, 30%, and 40%, the strength of PU/PCL scaffolds started to decrease to 8.9±1.1 MPa, 7.6±0.6 MPa, and 5.3±0.6 MPa, respectively. The highest strength was observed for the 90/10 PU/ PCL scaffolds and no cytotoxicity was detected.

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Authors and Affiliations

  1. Department of Biomedical Engineering, Daelim University, Anyang, Gyeonggi, 13916, Korea

    Gayeon Oh, Jeongwon Rho & Deuk Yong Lee

  2. Energy and Environmental Division, Korea Institute of Ceramic Engineering and Technology, Jinju, Gyeongnam, 52851, Korea

    Myung-Hyun Lee

  3. Vericom Co., Ltd., Anyang, Gyeonggi, 14087, Korea

    Young-Zu Kim

Authors
  1. Gayeon Oh
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  2. Jeongwon Rho
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  3. Deuk Yong Lee
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  4. Myung-Hyun Lee
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  5. Young-Zu Kim
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Correspondence to Deuk Yong Lee.

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Oh, G., Rho, J., Lee, D.Y. et al. Synthesis and characterization of electrospun PU/PCL hybrid scaffolds. Macromol. Res. 26, 48–53 (2018). https://doi.org/10.1007/s13233-018-6005-4

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  • DOI: https://doi.org/10.1007/s13233-018-6005-4

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