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High Pressure Inactivation of HAV Within Mussels

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Abstract

The potential of high pressure processing to inactivate hepatitis A virus (HAV) within Mediterranean mussels (Mytilus galloprovincialis) and blue mussels (Mytilus edulis) was evaluated. HAV was bioaccumulated within mussels to approximately 6-log10 PFU by exposure of mussels to HAV-contaminated seawater. After shucking, 5 min pressure treatments of 300, 325, 350, 375, and 400 MegaPascals (MPa) were performed at room temperature (18–22°C). For blue mussels, log10 PFU reductions of HAV averaged 2.1 and 3.6 for treatments of 350 and 400 MPa, while for Mediterranean mussels reductions of 1.7 and 2.9 log10 PFU MPa were observed for equivalent treatments. These results demonstrate that high pressure processing is capable of inactivating HAV within mussels.

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Acknowledgments

We wish to thank Gloria Meade (USDA, Dover DE) and Valeriana Colao (University of Bari) for technical assistance. We also wish to thank Gary Richards (USDA, Dover, DE, USA) and Pina Fratamico (USDA, Wyndmoor, PA, USA) for critical review of the manuscript.

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Mention of trade names or commercial products in this article is solely for the purpose of providing specific information and does not imply recommendation or endorsement by the U.S. Department of Agriculture.

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Authors and Affiliations

  1. Department of Veterinary and Public Health, University of Bari, 70010, Velanzano, Bari, Italy

    Valentina Terio, Giuseppina Tantillo, Vito Martella, Pietro Di Pinto & Canio Buonavoglia

  2. U.S. Department of Agriculture, Agricultural Research Service, Microbial Food Safety Research Unit, James W. W. Baker Center, Delaware State University, Dover, DE, 19901, USA

    David H. Kingsley

Authors
  1. Valentina Terio
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  2. Giuseppina Tantillo
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  4. Pietro Di Pinto
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  6. David H. Kingsley
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Correspondence to David H. Kingsley.

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Terio, V., Tantillo, G., Martella, V. et al. High Pressure Inactivation of HAV Within Mussels. Food Environ Virol 2, 83–88 (2010). https://doi.org/10.1007/s12560-010-9032-7

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  • DOI: https://doi.org/10.1007/s12560-010-9032-7

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