Skip to main content
Log in

Gender Difference in Cardiovascular Risk Factors among Older Persons in Northern Iran

  • Published:
Ageing International Aims and scope Submit manuscript

Abstract

Cardiovascular disease is the first cause of death among older persons worldwide. Therefore, assessing the characteristics of cardiovascular risk factors in the elderly should become a priority especially in populations with different dietary and cultural characteristics. Determining the gender difference in the prevalence of cardiovascular risk factors among elderly population in northern Iran. This is a cross sectional study in a representative sample of urban population from14 cities in northern Iran. Subjects 15 year-old and older were interviewed and examined by a trained research team. Blood samples were drawn for biochemical testing. Data analysis was done using SPSS 14 software and χ 2 test was used. For the aims of this study only data obtained from subjects 60 year old and older were included. From 2282 subjects in the whole study population, 291 (12.7 %) subjects were older than 60 years. From them 51.5 % were male, 42.1 % were illiterate and 9 % had academic education (more than 12th grade). 27.4 % males and 2.1 % females were smokers (ρ < 0.0001). Hypertension was reported in 54.9 % males and 81 % females (ρ < 0.0001). 50.7 % males and 72.1 % females had dyslipidemia (ρ < 0.0001), 24 % males and 35.5 % females were diabetic (ρ < 0.04). Only 48.2 % males and 22.6 % females had normal weight with the rest being either overweight or obese (ρ < 0.0001). In contrast to other demographic studies, and with the exception of smoking, the prevalence of cardiovascular risk factors in Iran is higher in older women in comparison to men. These findings indicate that a comprehensive national program for management of cardiovascular diseases in the elderly, with emphasis on older women, is urgently needed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  • Alberta, K. G., & Zimmer, P. Z. (1998). Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabetic Medicine, 15(7), 539–553.

    Article  Google Scholar 

  • Alikhani, S. (2005). A national profile of NCD risk factors in Iran. Technical unit for oncommunicable diseases risk factor survallence. CDC, Ministery of health and medical education.

  • Aronow, W. S. (2001). Approach to symptomatic coronary disease in the elderly: time to change? Lancet, 358, 945–946.

    Article  Google Scholar 

  • Azizi, F., et al. (2001). Tehran lipid and glucose study report. Endocrinology and metabolism Research center.

  • Baecke, J. A. H., Burema, J., & Frıjters, J. E. R. (1982). A short questionnaire for the measurement of habitual physical activity in epidemiological Studies. The American Journal of Clinical Nutrition, 36, 936–942.

    Google Scholar 

  • Balkau, B., & Charles, M. A. (1999). Comment on the provisional report from the WHO consultation. European Group for the Study of Insulin Resistance (EGIR). Diabetic Medicine, 16(5), 442–443.

    Article  Google Scholar 

  • Casiglia, E., & Palatini, P. (1998). Cardiovascular risk factors in the elderly. Journal of Human Hypertension, 12, 575–581.

    Article  Google Scholar 

  • Casiglia, E., Tikhonoff, V., Caffi, S., Bascelli, A., Schiavon, L., Guidotti, F., Saugo, M., Giacomazzo, M., Martini, B., Mazza, A., D’Este, D., & Pessina, A. C. (2008). Menopause does not affect blood pressure and risk profile, and menopausal women do not become similar to men. Journal of Hypertension, 26, 1983–1992.

    Article  Google Scholar 

  • Chobanian, A. V., et al. (2003). Seventh report of the Joint National Committee on prevention, detection, evaluation and treatment of high blood pressure. Hypertension, 42, 1206–1252.

    Article  Google Scholar 

  • de Araujo Alencar, N., de Assuncao Ferreira, M., Cleria Bezerra, J., et al. (2009). Levels of physical activity and quality of life in elderly women practitioners of formal and non-formal physical activities. Acta Medica Lituanica, 16(3–4), 155–158.

    Article  Google Scholar 

  • Einhorn, D., Reaven, G. M., Cobin, R. H., Ford, E., Ganda, O. P., Handelsman, Y., et al. (2003). American College of Endocrinology position statement on the insulin resistance syndrome. Endocrine Practice, 9(3), 237–252.

    Google Scholar 

  • Folsom, A. R., Szklo, M., Stevens, J., Liao, F., Smith, R., & Eckfeldt, J. H. (1997). A prospective study of coronary heart disease in relation to fasting insulin, glucose, and diabetes: the Atherosclerosis Risk in Communities (ARIC) study. Diabetes Care, 20, 935–942.

    Article  Google Scholar 

  • Jackson, R., Chambless, L., Higgins, M., Kuulasmaa, K., Wijnberg, L., & Williams, D. (1997). (WHO MONICA project and ARIC study) Sex differences in ischaemic heart disease mortality and risk factors in 46 communities: an ecologic analysis. Cardiovascular Risk Factors, 7, 43–54.

    Google Scholar 

  • Jousilahti, P., Vartiainen, E., Tuomilehto, J., & Puska, P. (1999). Sex, age, cardiovascular risk factors and coronary heart disease, a prospective follow-up study of 14786 middle-aged men and women in Finland. Circulation, 99, 1165–1172.

    Article  Google Scholar 

  • Kanaya, A. M., Grady, D., & Barrett-Connor, E. (2002). Explaining the sex difference in coronary heart disease mortality among patients with type 2 diabetes mellitus: a meta-analysis. Archives of Internal Medicine, 162, 1737–1745.

    Article  Google Scholar 

  • Lawlor, D. A., Bedford, C., Taylor, M., & Ebrahim, S. (2003). Geographical variation in cardiovascular disease, risk factors, and their control in older women: British Women’s Heart and Health Study. Journal of Epidemiology and Community Health, 57, 134–140.

    Article  Google Scholar 

  • Lin, Y.-C., Chu, F.-Y., Fu, C.-C., & Chen, J.-D. (2004). Prevalence and risk factors for angina in elderly Taiwanese. Journal of Gerontology: Medical Sciences, 59A(2), 161–165.

    Article  Google Scholar 

  • Masharani, U., Goldfine, I. D., & Youngren, J. F. (2009). Influence of gender on the relationship between insulin sensitivity, adiposity, and plasma lipids in lean nondiabetic subjects. Metabolism, Clinical and Experimental, 58, 1602–1608.

    Article  Google Scholar 

  • McNeill, A. M., Katz, R., Girmanw, C. J., Rosamond, W. D., Wagenknecht, L. E., Barzilay, J. I., Tracy, R. P., Savage, P. J., & Jackson, S. A. (2006). Metabolic syndrome and cardiovascular disease in older people: the cardiovascular health study. Journal of American Geriatrics Society, 54(9), 1317–1324.

    Article  Google Scholar 

  • Meisinger, C., Thorand, B., Schneider, A., et al. (2002). Sex differences in risk factors for incident type 2 diabetes mellitus. Archives of Internal Medicine, 162, 82–89.

    Article  Google Scholar 

  • Meisinger, C., Doring, A., & Heier, M. (2008). Blood pressure and risk of type 2 diabetes mellitus in men and women from the general population: the Monitoring Trends and Determinants on Cardiovascular Diseases/ Cooperative Health Research in the Region of Augsburg Cohort Study. Journal of Hypertension, 26, 1809–1815.

    Article  Google Scholar 

  • NCEP. (2001). Executive Summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). JAMA, 285(19), 2486–2497.

    Article  Google Scholar 

  • Njolstad, I., Arnesen, E., & Lund-Larsen, P. G. (1996). Smoking, serum lipids, blood pressure and sex differences in myocardial infarction: a 12 –year follow-up of the finnmark study. Circulation, 93, 450–456.

    Article  Google Scholar 

  • Ozkara, A., Turgut, F., Kanbay, M., Selcoki, Y., & Akcay, A. (2008). Population based cardiovascular risk factors in the elderly in Turkey: a cross-sectional survey. Central European Journal of Medicine, 3(2), 173–178.

    Article  Google Scholar 

  • Parashar, S., Katz, R., & Smith, N. L. (2009). Race, gender, and mortality in adults >65 years of age with incident heart failure (from the Cardiovascular Health Study). The American Journal of Cardiology, 103, 1120–1127.

    Article  Google Scholar 

  • Regitz-Zagrosek, V., Lehmkuhl, E., & Weickert, M. O. (2006). Gender differences in the metabolic syndrome and their role for cardiovascular disease. Clinical Research in Cardiology, 95, 136–147.

    Article  Google Scholar 

  • Regnault, V., Thomas, F., Safar, M. E., Osborne-Pellegrin, M., Khalil, R. A., Pannier, B., & Lacolley, P. (2012). Sex difference in cardiovascular risk. Journal of the American College of Cardiology, 59, 1771–1777.

    Article  Google Scholar 

  • Sainsbury, R. (1991). Modifiable cardiovascular risk factors in the elderly. Journal of the Hong Kong Medical Association, 43(4), 193–199.

    Google Scholar 

  • Scherr, C., & Ribeiro, J. P. (2009). Gender, age, social level and cardiovascular risk factors: considerations on the Brazilian reality. Arquivos Brasileiros de Cardiologia, 93(3), e42–e44.

    Article  Google Scholar 

  • Statistic Center of Iran. (2006). Country Population Urban and Rural Areas. In: http://www.amar.org.ir/default.aspx?tabid=320. 18/01/20210.

  • Vaccarino, V., Badimon, L., Corti, R., de Wit, C., Dorobantu, M., Hall, A., Koller, A., Marzilli, M., Pries, A., & Bugiardini, R. (2011). Ischaemic heart disease in women: are there sex differences in pathophysiology and risk factors? Cardiovascular Research, 90, 9–17.

    Article  Google Scholar 

  • World Health Organization. (1990). Part III, population survey: section 1, population survey data component: procedures for responders—blood pressure measurement. In: WHO MONICA Project. MONICA Manual (pp. 12–14). Geneva: World Health Organization.

  • World Health Organization. (2010a). Gender and Ageing. In: http://www.who.int/ageing/gender/en/index.html. 18/01/2010.

  • World Health Organization. (2010b). Older people and Primary Health Care (PHC). In: http://www.who.int/ageing/primary_health_care/en/index.html. 18/01/2010.

  • World Health Organization. (2010c). The SuRF Report 1, Surveillance of Risk factors related to noncommunicable diseases: Current status of global data. In: http://whqlibdoc.who.int/publications/2003/9241580305.pdf/18/01/2010.

  • Zambon, S., Zanoni, S., Romanato, G., Corti, M. C., Noale, M., Sartori, L., Musaccchio, E., Baggio, G., Crepaldi, G., & Manzato, E. (2009). Metabolic syndrome and all cause and cardiovascular mortality in an Italian elderly population. Diabetes Care, 32, 153–159.

    Article  Google Scholar 

  • Zhang, Y., Agnoletti, D., Iaria, P., et al. (2012). Gender difference in cardiovascular risk factors in the elderly with cardiovascular disease in the last stage of lifespan: The PROTEGER study. International Journal of Cardiology, 155, 144–148.

    Article  Google Scholar 

Download references

Acknowledgments

This study was supported by grants from Financial vice chancellorship of municipality of Guilan Province. We thank Dr Arman Mazooji at the Danesh Laboratory for laboratory testing. We also thank Sharareh Kiabi, Azam Jahangir Bloorchian and all health centers staff of Guilan province. Finally thanks to the Clinical Research development Center in Pour –Sina hospital in Rasht, Iran.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Z. Mohtasham-Amiri.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Barzigar, A., Mohtasham-Amiri, Z., Rahimi-Kolamroudi, H. et al. Gender Difference in Cardiovascular Risk Factors among Older Persons in Northern Iran. Ageing Int 38, 233–244 (2013). https://doi.org/10.1007/s12126-012-9177-9

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12126-012-9177-9

Keywords

Navigation