Abstract
One of the activities that geneticists pursue is the generation of genetic maps of organisms that chart the locations of the different genes on the chromosomes. Damodar Dharmanada Kosambi was not a geneticist by training and profession, but amathematician. Yet, in 1944, Kosambi wrote a classic paper about mapping function in genetics in the journal Annals of Eugenics. His lone paper in genetics was tilted ‘The estimation of map distance from recombination values’. The mapping function that Kosambi derived is still widely used by geneticists the world over for the mapping of genomes.
Similar content being viewed by others
Suggested reading
D D Kosambi, The estimation of map distance from recombination values, Annals of Eugenics, Vol.12, pp.172–175, 1944.
W Bateson, E R Saun-ders and R C Punnet, Experimental studies in the physiology of heredity, Reports to the Evolution Committee of the Royal Society, Vol.2, pp.80–99, 1905.
T H Morgan and C B Bridges, Sex linked inheritance in Drosophila, Carnegie Institution of Washington. p.88, 1916.
J B S Haldane, The combination of linkage values, and the calculation of distance between linked factors, Journal of Genetics, Vol.8, pp.299–309, 1919.
B H Liu, Statistical Genomics: Linkage, Mapping, and QTL Analysis, CRC Press, p.611, 1997.
M Huehn, Random variability of map distances based on Kosambi’s and Haldane’s mapping functions, J. Appl. Genet., Vol.51, pp.27–31, 2010.
Author information
Authors and Affiliations
Corresponding author
Additional information
K K Vinod is a Senior Scientist at the Rice Breeding and Genetics Research Centre, Indian Agricultural Research Institute, Aduthurai, Tamil Nadu. His research interests are on genetics and breeding of rice especially on tolerance to abiotic stresses like salinity and low nutrients. He works on QTL mapping and marker assisted selection for low nitrogen and phosphorus response, drought tolerance and grain quality in rice.
Rights and permissions
About this article
Cite this article
Vinod, K.K. Kosambi and the genetic mapping function. Reson 16, 540–550 (2011). https://doi.org/10.1007/s12045-011-0060-x
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12045-011-0060-x