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Magnetic resonance imaging of the proximal tibial epiphysis: could it be helpful in forensic age estimation?

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Abstract

There is an increasing demand for age estimations of living persons who are involved in civil and criminal procedures but lack a valid birth certificate indicating their date of birth. Several studies have recommended the application of magnetic resonance imaging (MRI) and assessment of the stage of epiphyseal fusion in age estimation. This study involved retrospective MRI analysis of 335 cases (217 males and 118 females) whose ages ranged from 8 to 28 years (yrs). We assessed the degree of ossification of the proximal tibial epiphysis depending on the classifications of Schmeling and Kellinghaus used for the main stages (I, II, III, IV & V) and substages (IIa, b, c & IIIa, b, c). Significant differences between males and females at stages IIIc, IV and V (p < 0.001) were observed. Additionally, the ossification of the proximal tibial epiphyses occurred earlier in females than in males (2–4 yrs). The mean of ages in stage IV was approximately 18.6 yrs. in females and 22.5 yrs. in males, meaning that stage IV can be used as a valuable forensic marker to determine whether the person in question has reached the age of 18 yrs. We concluded that the application of MRI in the assessment of the ossification status of the proximal tibial epiphysis could be helpful in age estimation for various forensic purposes.

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References

  1. Schmeling A, Grundmann C, Fuhrmann A, Kaatsch HJ, Knell B, Ramsthaler F, et al. Criteria for age estimation in living individuals. Int J Legal Med. 2008;122:457–60.

    Article  CAS  PubMed  Google Scholar 

  2. Serin J, Rérolle C, Pucheux J, Dedouit F, Telmon N, Savall F, et al. Contribution of magnetic resonance imaging of the wrist and hand to forensic age assessment. Int J Legal Med. 2016;130:1121–8.

    Article  PubMed  Google Scholar 

  3. Kellinghaus M, Schulz R, Vieth V, Schmidt S, Schmeling A. Forensic age estimation in living subjects based on the ossification status of the medial clavicular epiphysis as revealed by thin-slice multidetector computed tomography. Int J Legal Med. 2010;124:149–54.

    Article  PubMed  Google Scholar 

  4. Hillewig E, Degroote JE, Van der Paelt T, Visscher A, Vandemaele P, Lutin B, et al. Magnetic resonance imaging of the sternal extremity of the clavicle in forensic age estimation: towards more sound age estimates. Int J Legal Med. 2013;127:677–89.

    Article  CAS  PubMed  Google Scholar 

  5. Ekizoglu O, Inci E, Ors S, Hocaoglu E, Can IO, Basa CD, et al. Forensic age diagnostics by magnetic resonance imaging of the proximal humeral epiphysis. Int J Legal Med. 2019;133:249–56.

    Article  PubMed  Google Scholar 

  6. Timme M, Ottow C, Schulz R, Pfeiffer H, Heindel W, Vieth V, et al. Magnetic resonance imaging of the distal radial epiphysis: a new criterion of maturity for determining whether the age of 18 has been completed? Int J Legal Med. 2017;131:579–84.

    Article  CAS  PubMed  Google Scholar 

  7. Ekizoglu O, Hocaoglu E, Inci E, Sayin I, Solmaz D, Bilgili MG, et al. Forensic age estimation by the Schmeling method: computed tomography analysis of the medial clavicular epiphysis. Int J Legal Med. 2015;129:203–10.

    Article  PubMed  Google Scholar 

  8. Galić I, Mihanović F, Giuliodori A, Conforti F, Cingolani M, Cameriere R. Accuracy of scoring of the epiphyses at the knee joint (SKJ) for assessing legal adult age of 18 years. Int J Legal Med. 2016;130:1129–42.

    Article  PubMed  Google Scholar 

  9. Schmeling A, Schulz R, Reisinger W, Mühler M, Wernecke KD, Geserick G, et al. Studies on the time frame for ossification of medial clavicular epiphyseal cartilage in conventional radiography. Int J Legal Med. 2004;118:5–8.

    Article  PubMed  Google Scholar 

  10. Kellinghaus M, Schulz R, Vieth V, Schmidt S, Pfeiffer H, Schmeling A. Enhanced possibilities to make statements on the ossification status of the medial clavicular epiphysis using an amplified staging scheme in evaluating thin-slice C CT scans. Int J Legal Med. 2010;124:321–5.

    Article  PubMed  Google Scholar 

  11. Krämer JA, Schmidt S, Jürgens KU, Lentschig M, Schmeling A, Vieth V. The use of magnetic resonance imaging to examine ossification of the proximal tibial epiphysis for forensic age estimation in living individuals. Forensic Sci Med Pathol. 2014;10:306–13.

    Article  CAS  PubMed  Google Scholar 

  12. Hillewig E, De Tobel J, Cuche O, Vandemaele P, Piette M, Verstraete K. Magnetic resonance imaging of the medial extremity of the clavicle in forensic bone age determination: a new four-minute approach. Eur Radiol. 2011;21:757–67.

    Article  PubMed  Google Scholar 

  13. Altman DG. Some common problems in medical research. In: Altman DG, editor. Practical statistics for medical research. New York: Chapman & Hall; 1991. p. 396–403.

    Google Scholar 

  14. Ekizoglu O, Inci E, Ors S, Kacmaz IE, Basa CD, Can IO, et al. Applicability of T1-weighted MRI in the assessment of forensic age based on the epiphyseal closure of the humeral head. Int J Legal Med. 2019;133:241–8.

    Article  PubMed  Google Scholar 

  15. Saint-Martin P, Rérolle C, Pucheux J, Dedouit F, Telmon N. Contribution of distal femur MRI to the determination of the 18-year limit in forensic age estimation. Int J Legal Med. 2015;129:619.

    Article  PubMed  Google Scholar 

  16. O’Connor JE, Bogue C, Spence LD, Last J. A method to establish the relationship between chronological age and stage of union from radiographic assessment of epiphyseal fusion at the knee: an Irish population study. J Anat. 2008;212:198–209.

    Article  PubMed  PubMed Central  Google Scholar 

  17. Pyle SI, Hoerr NL. Radiographic atlas of skeletal development of the knee; a standard of reference. Springfield: Thomas; 1955.

    Google Scholar 

  18. Cardoso HF. Epiphyseal union at the innominate and lower limb in a modern Portuguese skeletal sample, and age estimation in adolescent and young adult male and female skeletons. Am J Phys Anthropol. 2008;135:161–70.

    Article  PubMed  Google Scholar 

  19. Coqueugnit H, Weaver TD. Brief communication: infracranial maturation in the skeletal collection from Coimbra Portugal: new aging standards for epiphyseal union. Am J Phys Anthropol. 2007;134:424–37.

    Article  Google Scholar 

  20. Saint-Martin P, Rérolle C, Dedouit F, Bouilleau L, Rousseau H, Rougé D, et al. Age estimation by magnetic resonance imaging of the distal tibial epiphysis and the calcaneum. Int J Legal Med. 2013;127:1023–30.

    Article  PubMed  Google Scholar 

  21. Bassed RB, Briggs C, Drummer OH. Age estimation using CT imaging of the third molar tooth, the medial clavicular epiphysis, and the spheno-occipital synchondrosis: a multifactorial approach. Forensic Sci Int. 2011;212:273.

    Article  PubMed  Google Scholar 

  22. Franklin D. Forensic age estimation in human skeletal remains: current concepts and future directions. Legal Med. 2010;12:1–7.

    Article  PubMed  Google Scholar 

  23. Dedouit F, Saint-Martin P, Mokrane FZ, Savall F, Rousseau H, Crubézy E, et al. Virtual anthropology: useful radiological tools for age assessment in clinical forensic medicine and thanatology. La Radiologia Medica. 2015;120:874–86.

    Article  PubMed  Google Scholar 

  24. Dedouit F, Auriol J, Rousseau H, Rougé D, Crubézy E, Telmon N. Age assessment by magnetic resonance imaging of the knee: a preliminary study. Forensic Sci Int. 2012;217:232.

    Article  PubMed  Google Scholar 

  25. Ekizoglu O, Hocaoglu E, Inci E, Can IO, Aksoy S, Kazimoglu C. Forensic age estimation via 3-T magnetic resonance imaging of ossification of the proximal tibial and distal femoral epiphyses: use of a T2-weighted fast spin-echo technique. Forensic Sci Int. 2015;260:102.

    PubMed  Google Scholar 

  26. Cunha E, Baccino E, Martrille L, Ramsthaler F, Prieto J, Schuliar Y, et al. The problem of aging human remains and living individuals: a review. Forensic Sci Int. 2009;193:1–13.

    Article  CAS  PubMed  Google Scholar 

  27. Ekizoglu O, Hocaoglu E, Inci E, Can IO, Aksoy S, Sayin I. Estimation of forensic age using substages of ossification of the medial clavicle in living individuals. Int J Legal Med. 2015;129:1259–64.

    Article  PubMed  Google Scholar 

  28. El Dine FMMB, Hebatallah HMH. Ontogenetic study of the scapula among some Egyptians: forensic implications in age and sex estimation using multidetector computed tomography. Egyptian J Forensic Sci. 2016;6:56–77.

    Article  Google Scholar 

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Acknowledgements

We would like to express our sincere appreciation to Prof. Mai Samir for her valuable guidance and to all members of the Radiology Department for their encouragement.

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Correspondence to Eman Ahmed Alaa El-Din.

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The study protocol was approved by The Institutional Review Board (IRB) of the Faculty of Medicine, Zagazig University and the Radiology Department. Ethical considerations and confidentiality were respected.

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Informed consent was waived as the data used was completely anonymized.

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El-Din, E.A.A., Mostafa, H.E.S., Tantawy, E.F. et al. Magnetic resonance imaging of the proximal tibial epiphysis: could it be helpful in forensic age estimation?. Forensic Sci Med Pathol 15, 352–361 (2019). https://doi.org/10.1007/s12024-019-00116-3

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