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Recent Trends in Biologically Synthesized Metal Nanoparticles and their Biomedical Applications: a Review

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Abstract

In recent years, biologically synthesized metal nanoparticles have emerged as a dynamic field of research with significant implications for biomedical applications. This review explores the latest trends in the synthesis of metal nanoparticles using biological methods, encompassing plant extracts and microorganisms such as bacteria, yeasts, and fungi. These innovative approaches offer a sustainable, cost-effective, and environmentally friendly alternative to conventional chemical synthesis methods. Moreover, this review delves into the multifaceted biomedical applications of biologically synthesized metal nanoparticles. These applications include drug delivery systems, diagnostics, therapeutics, and imaging technologies, showcasing the versatility and promise of these nanomaterials in addressing contemporary biomedical challenges. In addition, the review addresses the critical issue of cytotoxicity, offering insights into the safety and viability of these biologically derived NPs for medical use. The exploration of recent trends and advancements in this field underscores the transformative potential of biologically synthesized metal nanoparticles in revolutionizing biomedical research and healthcare.

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Acknowledgements

The authors are thankful to the Faculty of Pharmacy, Integral University, Lucknow, for providing all the necessary facilities related to the present work (Manuscript Communication Number: IU/R&D/2022-MCN0001416).

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Authors and Affiliations

  1. Faculty of Pharmacy, Integral University, Dasauli-Kursi Road, Lucknow, India

    Laxmi Devi, Poonam Kushwaha & Tarique Mahmood Ansari

  2. Rameshwaram Institute of Technology and Management, Lucknow, 222620, India

    Laxmi Devi

  3. Dr. Ashvil Pharmaceuticals Private Limited, Bangra, Mauranipur, Jhansi, Uttar Pradesh, 284205, India

    Laxmi Devi & Ashish Kumar

  4. Government Medical College, Jalaun, Orai, Uttar Pradesh, 285001, India

    Ashish Kumar

  5. Maharani Laxmi Bai Medical College, Jhansi, Uttar Pradesh, 284001, India

    Amit Rao

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P.K. conceived and designed the study, and wrote the first draft of the manuscript, S.S. carried out the research, B.S. and M.A participated in the analysis and interpretation of data. All authors contributed to and approved the final draft of the manuscript.

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Correspondence to Poonam Kushwaha.

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Devi, L., Kushwaha, P., Ansari, T.M. et al. Recent Trends in Biologically Synthesized Metal Nanoparticles and their Biomedical Applications: a Review. Biol Trace Elem Res 202, 3383–3399 (2024). https://doi.org/10.1007/s12011-023-03920-9

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