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Effects of Dietary Selenium Against Lead Toxicity Are Related to the Ion Profile in Chicken Muscle

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Abstract

Complex antagonistic interactions between Selenium (Se) and heavy metals have been reported in previous studies. However, little is known regarding the effects of Se on lead (Pb)-induced toxicity and the ion profile in the muscles of chickens. In this present study, we fed chickens either Se or Pb or both Se and Pb supplement and later analyzed the concentrations of 26 ions in chicken muscle tissues. We determined that a Se- and Pb-containing diets significantly affected microelements in chicken muscle. Treatment with Se increased the content of Se but resulted in a reduced concentration of Cu, As, Cd, Sn, Hg, and Ba. Treatment with Pb increased concentrations of Ni while reducing those of B, V, Cr, Fe, Co, Cu, Zn, and Mo. Moreover, Se also reduced the concentration of Pb, Zn, Co, Fe, V, and Cr, which in contrast were induced by Pb. Additionally, we also found that synergistic and antagonistic interactions existed between Se and Pb supplementation. Our findings suggested that Se can exert a negative effect on Pb in chicken muscle tissues and may be related to changes in ion profiles.

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Acknowledgments

This work was supported by China Postdoctoral Science Foundation (No.2012M520702), the Startup Foundation for Doctors of Northeast Agricultural University, China (No. 2012RCB92), Heilongjiang Provincial Department of Education Science and Technology research project (No.12541024), the Young Talents Project of Northeast Agricultural University (No.14QC18), and the International Postdoctoral Exchange Fellowship Program (No.20130006). We also thank the “Elsevier Language Editing Services” who help us to correct the language.

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Authors and Affiliations

  1. College of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, People’s Republic of China

    Xi Jin, Xiao Hua Teng & Jing Fu

  2. Department of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, People’s Republic of China

    Chun Peng Liu

  3. Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14850, USA

    Jing Fu

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  1. Xi Jin
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  2. Chun Peng Liu
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Correspondence to Xiao Hua Teng or Jing Fu.

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All procedures used in this study were approved by the Institutional Animal Care and Use Committee of Northeast Agricultural University.

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Jin, X., Liu, C.P., Teng, X.H. et al. Effects of Dietary Selenium Against Lead Toxicity Are Related to the Ion Profile in Chicken Muscle. Biol Trace Elem Res 172, 496–503 (2016). https://doi.org/10.1007/s12011-015-0585-z

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  • DOI: https://doi.org/10.1007/s12011-015-0585-z

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