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Selenomethionine: an Effective Selenium Source for Sow to Improve Se Distribution, Antioxidant Status, and Growth Performance of Pig Offspring

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Abstract

The present study was to investigate the efficiency of maternal selenomethionine intake on growth performance, Se distribution, and antioxidant status of pig offspring by comparing with sodium selenite. A total of 12 sows (Landrace × Yorkshire) with same pregnancy were randomly divided into two groups; each group was replicated six times. These two groups received the same basal gestation and lactation diets containing 0.04 mg Se/kg, supplemented with 0.3 mg Se/kg sodium selenite and selenomethionine (i.e., seneno-dl-methylseleno), respectively. The feeding trial lasted for 60 days, with 32 and 28 days for gestation and lactation period, respectively. Compared with sodium selenite, maternal selenomethionine intake significantly (p < 0.05) increased the daily weight gain of piglet from birth to weaning. The Se concentration in the colostrum and milk and tissue Se content of piglets were significantly higher (p < 0.05) in the selenomethionine-treated group. The antioxidant status was greatly improved in piglets of selenomethionine-treated group and was illuminated by the increased total antioxidant capability, glutathione peroxidase, superoxide dismutase, and glutathione, and decreased the malondialdehyde level in the organs of piglets. The increased (p < 0.05) triiodothyronine (T3) and decreased (p < 0.05) thyroxine (T4) concentration indicated the improved protein synthesis and energy production in the selenomethionine-treated group. The increased (p < 0.05) pancreatic digestive enzymes of protease, amylase, and lipase activities indicated that maternal selenomethionine intake may have a positive effect on the degradation and absorption of nutrients in its piglets. In summary, we concluded that maternal selenomethionine intake increased Se deposition, antioxidant status, and nutrient use efficiency, thus providing an effective way to improve the growth performance of piglets from birth to weaning.

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Acknowledgments

The financial support provided by the Program for Century Excellent Talents in University (project NECT-07-0758) and the National Basic Research Program of China (project 2004CB117505) is gratefully acknowledged.

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Authors and Affiliations

  1. Feed Science Institute, College of Animal Science, Zhejiang University, Hangzhou, 310029, People’s Republic of China

    Xiuan Zhan, Yanzhao Qie & Xing Li

  2. Laboratory of Animal Nutrition and Health, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, 410125, People’s Republic of China

    Min Wang

  3. Key Laboratory of Animal Physiology and Biochemistry, Ministry of Agriculture, Nanjing Agricultural University, Nanjing, 210095, People’s Republic of China

    RuQian Zhao

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  1. Xiuan Zhan
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  2. Yanzhao Qie
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  3. Min Wang
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  4. Xing Li
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  5. RuQian Zhao
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Correspondence to Xiuan Zhan.

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Zhan, X., Qie, Y., Wang, M. et al. Selenomethionine: an Effective Selenium Source for Sow to Improve Se Distribution, Antioxidant Status, and Growth Performance of Pig Offspring. Biol Trace Elem Res 142, 481–491 (2011). https://doi.org/10.1007/s12011-010-8817-8

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  • DOI: https://doi.org/10.1007/s12011-010-8817-8

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