Abstract
α-Terpineol (CAS No. 98-55-5) is a tertiary monoterpenoid alcohol widely and commonly used in the flavors and fragrances industry for its sensory properties. It is present in different natural sources, but its production is mostly based on chemical hydration using α-pinene or turpentine. Moreover, many bioprocesses for the microbial production of α-terpineol via biotransformation of monoterpenes (limonene, α- and β-pinenes) are also available in the literature. In addition to its traditional use, α-terpineol has also been evaluated in other application fields (e.g., medical), since some biological properties other than aroma, such as antioxidant, anti-inflammatory, antiproliferative, antimicrobial, and analgesic effects, among others, have been attributed to this compound. Therefore, this review presents an original compilation of data regarding the production (extraction directly from nature; chemical synthesis; via biotechnological process), the chemical and biological properties, and the current market and novel applications of α-terpineol to guide further research in this area. Considering the information presented, we believe that α-terpineol applications may transcend the flavors and fragrances industry in the future.
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Acknowledgments
The authors thank Espaço da Escrita – Coordenadoria Geral da Universidade (UNICAMP) for the language services provided.
Funding
Adones Sales received grant from Instituto Euvaldo Lodi (IEL/PR) and CNPq (grant number 350020/2018-3) and CAPES (process number 23038.000795/2018-61). This study was funded by the National Council of Technological and Scientific Development (CNPq) (grant number 400411/2016-4); the São Paulo Research Foundation (FAPESP) (grant number 2016/21619-7); and the Coordination for the Improvement of Higher Education Personnel (CAPES) (process number 23038.000795/2018-61, Finance Code 001). Moreover, Lorena de Oliveira Felipe is grateful to the Ministry of Education, Culture, Sports, Science and Technology (MEXT - Monbukagakusho) for the Doctoral Grant (recipient no. 177307) provided by the Japanese Government.
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Sales, A., Felipe, L.d.O. & Bicas, J.L. Production, Properties, and Applications of α-Terpineol. Food Bioprocess Technol 13, 1261–1279 (2020). https://doi.org/10.1007/s11947-020-02461-6
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DOI: https://doi.org/10.1007/s11947-020-02461-6