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Current Role of PCNL in Pediatric Urolithiasis

  • Minimally Invasive Surgery (V Bird and M Desai, Section Editors)
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Abstract

The incidence of pediatric stone disease has been increasing. Though there are geographical variations, there remains a common theme in that this is a high-risk population with regard to stone formation and recurrence. Consequently, it is important to keep the number of procedures performed to a minimum and to save the developing kidney from the deleterious effects of intervention. Of the number of available treatment options, Percutaneous Nephrolithotomy (PCNL) offers a number of distinct advantages albeit with its own set of concerns. In the present article, the current literature on PCNL in pediatric urolithiasis was reviewed by a MEDLINE/PubMed search that was limited to literature in the English language, with emphasis on the current state of art in PCNL. Within the last few years, there have been improvements in radiological techniques, particularly computed tomography (CT), with dedicated reconstructions and development of scoring systems leading to better preoperative planning. Also, there has been miniaturization of instruments, particularly smaller nephroscopes, innovative sheaths and the potential to use lasers as well as smaller pneumatic and ultrasound probes. The combination of these has led to various modifications, such as miniperc, microperc and ultra-mini perc techniques. These modifications have been shown to be associated with a decrease in morbidity and high clearance rates. In this article, we analyze the current role of PCNL and its modifications, in terms of the indications, techniques, results, and complications in management of pediatric urolithiasis.

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References

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  1. Schwarz RD, Dwyer NT. Pediatric kidney stones: long-term outcomes. Urology. 2006;67:812–6.

    Article  PubMed  Google Scholar 

  2. Erdenetsesteg G, Manohar T, Singh H, Desai MR. Endourologic management of pediatric urolithiasis: proposed clinical guidelines. J Endourol. 2006;20:737–48.

    Article  PubMed  Google Scholar 

  3. Sharma AP, Filler G. Epidemiology of pediatric urolithiasis. Indian J Urol. 2010;26:516–22.

    Article  PubMed Central  PubMed  Google Scholar 

  4. Türk C, Knoll T, Petrik A, et al. Guidelines on urolithiasis EAU. 2012. http://www.uroweb.org/gls/pdf/20_Urolithiasis_LR%20March%2013%202012.pdf.

    Google Scholar 

  5. Karabacak OR, Ipek B, Ozturk U, Demirel F, Saltas H, Altug U. Metabolic evaluation in stone disease metabolic differences between the pediatric and adult patients with stone disease. Urology. 2010;76(1):238–41.

    Article  PubMed  Google Scholar 

  6. Kieran K, Giel D, Morris B, Wan J, et al. Pediatric urolithiasis—does body mass index influence stone presentation and treatment? J Urol. 2010;184(4):1810–5.

    Article  PubMed  Google Scholar 

  7. Kim S, Luan X, Canning D, et al. Association between body mass index and urolithiasis in children. J Urol. 2011;186(4):1734–9.

    Article  PubMed Central  PubMed  Google Scholar 

  8. Coward RJ, Peters CJ, Duffy PG, Corry D, Kellett MJ, Choong S, et al. Epidemiology of pediatric renal stone disease in the UK. Arch Dis Child. 2003;88:962e5.

    Article  Google Scholar 

  9. Pietrow PK, Pope 4th JC, Adam MC, Shyr Y, Brock 3rd JW. Clinical outcome of pediatric stone disease. J Urol. 2002;167:670e3.

    Article  Google Scholar 

  10. Eelder JS. Urinary lithiasis. In: Behrman RE, Kliegman RM, Jenson HB, Stanton BF, editors. Nelson textbook of pediatrics. 18th ed. Philadelphia: Saunders; 2008. p. 2267–72.

    Google Scholar 

  11. Millliner DS. Urolithiasis. In: Avner ED, Harmon WE, Niaudet P, editors. Pediatric nephrology. 5th ed. Philadelphia: Lippincott Williams & Williams; 2003. p. 1091 [Chapter 57].

    Google Scholar 

  12. Smith SL, Somers JM, Broderick N, Halliday K. The role of plain radiograph and renal tract ultrasound in the management of children with renal tract calculi. Clin Radiol. 2000;55:708e10.

    Article  Google Scholar 

  13. Sternberg K, Greenfield SP, Williot P, Wan J. Pediatric stone disease: an evolving experience. J Urol. 2005;174:1711e4.

    Article  Google Scholar 

  14. Diament MJ, Malekzadeh M. Ultrasound and the diagnosis of renal and ureteral calculi. J Pediatr. 1986;109:980–3.

    Article  CAS  PubMed  Google Scholar 

  15. Strouse PJ, Bates DG, Bloom DA, et al. Non-contrast thin section helical CT of urinary tract calculi in children. Pediatr Radiol. 2002;32(5):326–32.

    Article  PubMed  Google Scholar 

  16. Palmer JS, Donaher ER, O’Riordan MA, et al. Diagnosis of pediatric urolithiasis: role of ultrasound and computerized tomography. J Urol. 2005;174(4 Pt 1):1413–6.

    Article  PubMed  Google Scholar 

  17. Cracco CM, Scoffone CM, Scarpa RM. New developments in percutaneous techniques for simple and complex branched renal stones. Curr Opin Urol. 2011;21:154–60.

    Article  PubMed  Google Scholar 

  18. Kalogeropoulou C, Kallidonis P, Liatsikos EN. Imaging in percutaneous nephrolithotomy. J Endourol. 2009;23:1571–7.

    Article  PubMed  Google Scholar 

  19. Okhunov Z, Friedlander JI, George AK, Duty BD, Moreira DM, Srinivasan AK, et al. S.T.O.N.E. nephrolithometry: novel surgical classification system for kidney calculi. Urology. 2013;81(6):1154–9.

    Article  PubMed  Google Scholar 

  20. Thomas K, Smith NC, Hegarty N, Glass JM. The Guy's stone score–grading the complexity of percutaneous nephrolithotomy procedures. Urology. 2011;78(2):277–81.

    Article  PubMed  Google Scholar 

  21. Mishra S, Sabnis RB, Desai M. Staghorn morphometry: a new tool for clinical classification and prediction model for percutaneous nephrolithotomy monotherapy. J Endourol. 2012;26(1):6–14.

    Article  PubMed  Google Scholar 

  22. Jeong CW, Jung J-W, Cha WH, Lee BK, Lee S, Jeong SJ, et al. Seoul National University renal stone complexity score for predicting stone-free rate after percutaneous nephrolithotomy. PLoS One. 2013;8(6):e65888.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  23. Ost MC, Lee BR. Urolithiasis in patients with spinal cord injuries: risk factors, management, and outcomes. Curr Opin Urol. 2006;16(2):93–9.

    Article  PubMed  Google Scholar 

  24. Osman M, Wendt-Nordahl G, Heger K, Michel MS, Alken P, Knoll T. Percutaneous nephrolithotomy with ultrasonography guided renal access: experience from over 300 cases. BJU Int. 2005;96(6):875–8.

    Article  PubMed  Google Scholar 

  25. Desai M. Ultrasonography-guided punctures-with and without puncture guide. J Endourol. 2009;23:1641–3.

    Article  PubMed  Google Scholar 

  26. Ganpule AP, Mishra S, Desai MR. Percutaneous nephrolithotomy for pediatric urolithiasis. Indian J Urol. 2010;26:549–54. This is a comprehensive review encompassing various facets of the subject available during the then available literature.

    Article  PubMed Central  PubMed  Google Scholar 

  27. Mishra S, Sharma R, Garg C, Kurien A, Sabnis R, Desai M. Prospective comparative study of miniperc and standard PNL for treatment of 1 to 2 cm size renal stone. BJU Int. 2011;108:896–9.

    PubMed  Google Scholar 

  28. Jackman SV, Docimo SG, Cadeddu JA, Bishoff JT, Kavoussi LR, Jarrett TW. The “mini-perc” technique: a less invasive alternative to percutaneous nephrolithotomy. World J Urol. 1998;16:371–4.

    Article  CAS  PubMed  Google Scholar 

  29. Desai MR, Sharma R, Mishra S, Sabnis RB, Stief C, Bader M. Single-step percutaneous nephrolithotomy (microperc): the initial clinical report. J Urol. 2011;186:140–5.

    Article  PubMed  Google Scholar 

  30. Penbegul N, Bodakci MN, Hatipoglu NK, Sancaktutar AA, Atar M, Cakmakci S, et al. Micro sheath for microperc: 14 gauge angiocath. J Endourol. 2013;27:835–9.

    Article  PubMed  Google Scholar 

  31. Sabnis RB, Ganesamoni R, Sarpal R. Miniperc: what is its current status? Curr Opin Urol. 2012;22(2):129–33.

    Article  PubMed  Google Scholar 

  32. Desai J, Zeng G, Zhao Z, Zhong W, Chen W, Wenqi W. A novel technique of ultra-mini-percutaneous nephrolithotomy: introduction and an initial experience for treatment of upper urinary calculi less than 2cm. BioMed Res Int. 2013;2013, 490793. 6 pages.

    Article  PubMed Central  PubMed  Google Scholar 

  33. Srisubat A, Potisat S, Lojanapiwat B, Setthawong V, Laopaiboon M. Extracorporeal shock wave lithotripsy (ESWL) versus percutaneous nephrolithotomy (PCNL) or retrograde intrarenal surgery (RIRS) for kidney stones. Cochrane Database Syst Rev. 2009;4: Article ID CD007044. doi:10.1002/14651858.CD007044.pub2.

  34. Resorlu B, Oguz U, Resorlu EB, Oztuna D, Unsal A. The impact of pelvicaliceal anatomy on the success of retrograde intrarenal surgery in patients with lower pole renal stones. Urology. 2012;79:61–6.

    Article  PubMed  Google Scholar 

  35. Woodside JR, Stevens GF, Stark GL, Borden TA, Ball WS. Percutaneous stone removal in children. J Urol. 1985;134:1166–7.

    CAS  PubMed  Google Scholar 

  36. Mor Y, Elmasry YE, Kellett MJ, Duffy PG. The role of percutaneous nephrolithotomy in the management of pediatric renal calculi. J Urol. 1997;158:1319–21.

    Article  CAS  PubMed  Google Scholar 

  37. Jackman SV, Hedican SP, Peters CA, Docimo SG. Percutaneous nephrolithotomy in infants and preschool age children: experience with a new technique. Urology. 1998;52:697.

    Article  CAS  PubMed  Google Scholar 

  38. Badawy H, Salama A, Eissa M, Kotb E, Moro H, et al. Percutaneous management of renal calculi: experience with percutaneous nephrolithotomy in 60 children. J Urol. 1999;162:1710–3.

    Article  CAS  PubMed  Google Scholar 

  39. Al-Shammari AM, Al-Otaibi K, Leonard MP, Hosking DH. Percutaneous nephrolithotomy in the pediatric population. J Urol. 1999;162:1721–4.

    Article  CAS  PubMed  Google Scholar 

  40. Zeren S, Satar N, Bayazit Y, Bayazit AK, Payasli K, Ozkeceli R. Percutaneous nephrolithotomy in the management of pediatric renal calculi. J Endourol. 2002;16:75.

    Article  PubMed  Google Scholar 

  41. Rizvi SA, Naqvi SA, Hussain Z, Hashmi A, Hussain M, Zafar MN, et al. Management of pediatric urolithiasis in Pakistan: experience with 1,440 children. J Urol. 2003;169:634.

    Article  CAS  PubMed  Google Scholar 

  42. Desai MR, Kukreja RA, Patel SH, Bapat SD. Percutaneous nephrolithotomy for complex pediatric renal calculus disease. J Endourol. 2004;18:23–7.

    Article  PubMed  Google Scholar 

  43. Salah MA, Toth C, Khan AM, Holman E. Percutaneous nephrolithotomy in children: experience with 138 cases in a developing country. World J Urol. 2004;22:277.

    Article  PubMed  Google Scholar 

  44. Holman E, Khan AM, Flasko T, Toth C, Salah MA. Endoscopic management of pediatric urolithiasis in a developing country. Urology. 2004;63(1):159–62. discussion 162.

    Article  PubMed  Google Scholar 

  45. Raza A, Turna B, Smith G, Moussa S, Tolley DA. Pediatric urolithiasis: 15 years of local experience with minimally invasive endourological management of pediatric calculi. J Urol. 2005;174:682–5.

    Article  PubMed  Google Scholar 

  46. Samad L, Aquil S, Zaidi Z. Pediatric percutaneous nephrolithotomy: setting new frontiers. BJU Int. 2006;97:359.

    Article  PubMed  Google Scholar 

  47. Shokeir AA, Sheir KZ, El-Nahas AR, El-Assmy AM, Eassa W, El-Kappany HA. Treatment of renal stones in children: a comparison between percutaneous nephrolithotomy and shock wave lithotripsy. J Urol. 2006;176:706–10. This was amongst one of the earlier and larger series, whereby a comparison was made between the two, in vogue techniques, to achieve stone clearance in pediatric age group.

    Article  PubMed  Google Scholar 

  48. Bilen CY, Kocak B, Kitirci G, Ozkaya O, Sarikaya S. Percutaneous nephrolithotomy in children: lessons learned in 5 years at a single institution. J Urol. 2007;177:1867.

    Article  PubMed  Google Scholar 

  49. Nouralizadeh A, Basiri A, Javaherforooshzadeh A, Soltani MH, Tajali F. Experience of percutaneous nephrolithotomy using adult sized instruments in children less than 5 years old. J Pediatr Urol. 2009;5:351–4.

    Article  PubMed  Google Scholar 

  50. Onal B, Dogan HS, Satar N, Bilen CY, Güneş A, Ozden E, et al. Factors affecting complication rates of percutaneous nephrolithotomy in children: results of a multi-institutional retrospective analysis by the pediatric stone disease study group of the turkish pediatric urology society. J Urol. 2014;191(3):777–82. One of the largest, multi-institutional contemporary study depicting the various factors affecting complication rates of percutaneous nephrolithotomy in children.

  51. Goyal NK, Goel A, Sankhwar SN, Singh V, Singh BP, Sinha RJ, et al. A critical appraisal of complications of percutaneous nephrolithotomy in pediatric patients using adult instruments. BJU Int. 2014;113(5):801–10.

  52. Veeratterapillay R, Shaw MB, Williams R, Haslam P, Lall A, De la Hunt M, et al. Safety and efficacy of percutaneous nephrolithotomy for the treatment of pediatric urolithiasis. Ann R Coll Surg Engl. 2012;94(8):588–92.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  53. Wah TM, Kidger L, Kennish S, Irving H, Najmaldin A. MINI PCNL in a pediatric population. Cardiovasc Intervent Radiol. 2013;36(1):249–54.

    PubMed  Google Scholar 

  54. Yan X, Al-Hayek S, Gan W, Zhu W, Li X, Guo H. Minimally invasive percutaneous nephrolithotomy in preschool age children with kidney calculi (including stones induced by melamine-contaminated milk powder). Pediatr Surg Int. 2012;28(10):1021–4.

    Article  PubMed  Google Scholar 

  55. Etemadian M, Maghsoudi R, Shadpour P, Mokhtari MR, Rezaeimehr B, Shati M. Pediatric percutaneous nephrolithotomy using adult sized instruments: our experience. Urol J. 2012;9(2):465–71.

    PubMed  Google Scholar 

  56. Kumar R, Anand A, Saxena V, Seth A, Dogra PN, Gupta NP. Safety and efficacy of PCNL for management of staghorn calculi in pediatric patients. J Pediatr Urol. 2011;7(3):248–51.

    Article  PubMed  Google Scholar 

  57. Anand A, Kumar R, Dogra PN, Seth A, Gupta NP. Safety and efficacy of a superior caliceal puncture in pediatric percutaneous nephrolithotomy. J Endourol. 2010;24(11):1725–8.

    Article  PubMed  Google Scholar 

  58. Unsal A, Resorlu B, Kara C, Bozkurt OF, Ozyuvali E. Safety and efficacy of percutaneous nephrolithotomy in infants, preschool age, and older children with different sizes of instruments. Urology. 2010;76(1):247–52.

    Article  PubMed  Google Scholar 

  59. Zeng G, Zhao Z, Zhao Z, Yuan J, Wu W, Zhong W. Percutaneous nephrolithotomy in infants: evaluation of a single-center experience. Urology. 2012;80(2):408–11.

    Article  PubMed  Google Scholar 

  60. Farahat WA, Kropp BP. Surgical treatment of pediatric urinary stones. AUA Updat Ser. 2007;26:21–8.

    Google Scholar 

  61. Segura JW, Patterson DE, LeRoy AJ, McGough PF, Barrett DM. Percutaneous removal of kidney stones: preliminary report. Mayo Clin Proc. 1982;57:615–9.

    CAS  PubMed  Google Scholar 

  62. Mahmud M, Zaidi Z. Percutaneous nephrolithotomy in children before school age: experience of a Pakistani centre. BJU Int. 2004;94:1352–4.

    Article  PubMed  Google Scholar 

  63. Guven S, Istanbulluoglu O, Ozturk A, et al. Percutaneous nephrolithotomy is highly efficient and safe in infants and children under 3 years of age. Urol Int. 2010;85:455–60.

    Article  PubMed  Google Scholar 

  64. Dawaba MS, Shokeir AA, Hafez AT, Shoma AM, El-Sherbiny MT, Mokhtar A, et al. Percutaneous nephrolithotomy in children: early and late anatomical and functional results. J Urol. 2004;172:1078–81.

    Article  PubMed  Google Scholar 

  65. Traxer O, Smith 3rd TG, Pearle MS, Corwin TS, Saboorian H, Cadeddu JA. Renal parenchymal injury after standard and mini percutaneous nephrostolithotomy. J Urol. 2001;165:1693–5. This study analyzed the impact of tract size on morbidity. This was later followed by studies that showed contradictory results.

    Article  CAS  PubMed  Google Scholar 

  66. Salah MA, Tállai B, Holman E, et al. Simultaneous bilateral percutaneous nephrolithotomy in children. BJU Int. 2005;95:137–9.

    Article  PubMed  Google Scholar 

  67. Guven S, Ozturk A, Arslan M, Istanbulluoglu O, Piskin M, Kilinc M. Simultaneous bilateral percutaneous nephrolithotomy in children: no need to delay. J Endourol. 2011;25(3):437–40.

    Article  PubMed  Google Scholar 

  68. Rodrigues PL, Rodrigues NF, Fonseca J, Lima E, Vilaça JL. Kidney targeting and puncturing during percutaneous nephrolithotomy: recent advances and future perspectives. J Endourol. 2013;27(7):826–34. The article addresses various innovations and upcoming techniques involved during the targeting and puncturing in percutaneous nephrolithotomy.

    Article  PubMed  Google Scholar 

  69. Tzeng BC, Wang CJ, Huang SW, Chang CH. Doppler ultrasound-guided percutaneous nephrolithotomy: a prospective randomized study. Urology. 2011;78:535–9.

    Article  PubMed  Google Scholar 

  70. Li ZC, Li K, Zhan HL, et al. Augmenting intraoperative ultrasound with preoperative magnetic resonance planning models for percutaneous renal access. Biomed Eng Online. 2012;11:60.

    Article  PubMed Central  PubMed  Google Scholar 

  71. Mozer P, Troccaz J, Stoianovici D. Urologic robots and future directions. Curr Opin Urol. 2009;19:114–9.

    Article  PubMed Central  PubMed  Google Scholar 

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Dr. Ravindra B. Sabnis, Dr. Jaspreet S. Chhabra, Dr. Arvind P. Ganpule, Dr. Sachin Abrol, and Dr. Mahesh R. Desai each declare no potential conflicts of interest.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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Correspondence to Ravindra B. Sabnis.

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This article is part of the Topical Collection on Minimally Invasive Surgery

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Sabnis, R.B., Chhabra, J.S., Ganpule, A.P. et al. Current Role of PCNL in Pediatric Urolithiasis. Curr Urol Rep 15, 423 (2014). https://doi.org/10.1007/s11934-014-0423-4

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