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Safety and efficacy of ultrasound-guided low-pressure perfusion mini-percutaneous nephrolithotomy in children aged 1–7 years: a retrospective observational study

  • Urology - Original Paper
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Abstract

Purpose

This article analyzed the safety and efficacy of ultrasound-guided mini-percutaneous nephrolithotomy (MPCNL) with low-pressure perfusion for the treatment of upper urinary tract stones in children.

Methods

The clinical data of 690 patients (805 renal units) aged 1–7 years were retrospectively analyzed in terms of postoperative outcome.

Results

The mean patient age was 3.7 ± 1.6 years, and the stone burden was 2.8 ± 2.1 cm2. A middle posterior calyceal puncture was created in 719 (89%) renal units, and 16F puncture tracts were the most common method used in 557 (69%) renal units. The stone-free rate was 711 (88%) renal units, and the mean operation time was 35 ± 15.3 min (between 15 and 110 min). Among all cases, the transfusion rate was 4 (0.6%) patients, and the mean decrease in hemoglobin was 1.3 ± 0.9 g/L. In addition, the incidence rates of fever, sepsis, perirenal effusion, and intraperitoneal effusion were 40 (5.9%), 3 (0.4%), 28 (4.1%), and 8 (1.2%) patients, respectively. After the operation, 348 patients were followed-up for 32.8 ± 11.3 months, and stone recurrence occurred in 136 (39%) of 348 patients.

Conclusions

This study suggests that ultrasound-guided MPCNL with low-pressure perfusion technology is a safe and feasible treatment.

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The data and materials in this manuscript are available for use.

Code availability

N/A.

Abbreviations

BMI:

Body mass index

CT:

Computed tomography

ESWL:

Extracorporeal shock wave lithotripsy

MPCNL:

Mini-percutaneous nephrolithotomy

PCNL:

Percutaneous nephrolithotomy

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Funding

The authors of this manuscript have no funding to disclose.

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Authors and Affiliations

  1. Department of Urology, Beijing Chao Yang Hospital, Capital Medical University, Beijing, 100020, China

    Zhi Qiu

  2. Department of Urology, Hotan People’s Hospital, Hotan, 848000, Xinjiang Uyghur Autonomous Region, China

    Zhi Qiu, Quan-bin Guo, Zakir Ablikim, Xu-wen Shi, Jiang-jiang Hou, Chang Chen, Mamat Hasanjan, Mamat Akbarjan & Abdukadir Anwar

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  1. Zhi Qiu
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Contributions

All authors contributed to the study conception and design. ZQ designed the study and wrote this manuscript; ZA, XWS, JJH, and CC performed the operations and collected the data; MH, MA, and AA collected the data and performed the statistical analysis. All authors read and approved the final manuscript.

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Correspondence to Zhi Qiu.

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Ethical approval was waived by the local Ethics Committee of China Capital Medical University in view of the retrospective nature of the study and all the procedures being performed were part of the routine care.

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Qiu, Z., Guo, Qb., Ablikim, Z. et al. Safety and efficacy of ultrasound-guided low-pressure perfusion mini-percutaneous nephrolithotomy in children aged 1–7 years: a retrospective observational study. Int Urol Nephrol 53, 1969–1976 (2021). https://doi.org/10.1007/s11255-021-02933-4

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  • DOI: https://doi.org/10.1007/s11255-021-02933-4

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