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Cardiovascular Disease and HIV Infection

  • Metabolic Complications and Comorbidity (JM Kilby, Section Editor)
  • Published:
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Abstract

The emergence of chronic disease complications in controlled HIV disease has changed the landscape of HIV clinical care. HIV infection confers an increased cardiovascular disease risk, which is thought to be due to a complex interplay of mechanistic factors. While traditional cardiovascular risk factors likely play a role, recent evidence suggests that HIV-associated inflammation and immune activation are important mediators of cardiovascular risk. It is unclear whether established preventative interventions for the general population are applicable to HIV-infected patients, and the need to translate mechanistic knowledge into HIV-specific clinical interventions represents an important priority. Developing strategies to prevent cardiovascular disease in HIV-infected individuals calls for a multidisciplinary approach and represents an opportunity to exert a major public health impact in an at-risk population.

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Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Virginia A. Triant declares that she has no conflict of interest.

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  1. Divisions of Infectious Diseases and General Medicine, Massachusetts General Hospital and Harvard Medical School, 50 Staniford Street, 9th Floor, Boston, MA, 02114, USA

    Virginia A. Triant

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Triant, V.A. Cardiovascular Disease and HIV Infection. Curr HIV/AIDS Rep 10, 199–206 (2013). https://doi.org/10.1007/s11904-013-0168-6

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