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Modified AHP-based decision-making model toward accurate selection of eligible maintenance media for production of taxanes in Taxus baccata callus culture

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Abstract

Attempts were made here to apply a modified analytic hierarchy process (AHP) approach based on refinement assay of dominated alternatives in monitoring the most reliable callus maintenance media (supplemented with l-glutamine and Casamino acid) of Taxus baccata callus cultures in terms of five criteria. Generally, regarding stem-derived calli, 6 out of 18 maintenance media were nominated as non-dominated alternatives, and following AHP ranking test Casamino acid-based media (i.e., A12, A15 and A19) were overall nominated as the premiere. Taking leaf-derived calli into account, only l-glutamine-based media in an ascending order of A8, A4, A6, A5, A9 and A3 were introduced as non-dominated alternatives. Such results connote that l-glutamine-based feeding appears to generate more significant results either for continuous calli growth or taxanes production. In contrast, regarding the second explant, stem, both amino acid supplies had fairly equal worth. Our findings, overall, demonstrate promising applications of the proposed AHP method regarding accurate selection of the best callus maintenance cultures of T. baccata for production of different taxanes including paclitaxel, Baccatin III and 10-deacetylbaccatin III. Similarly, this statistical approach could be also applicable for other crops, for instance, for accurate selection of the best callus cultures/media and consequently production improvement of a given plant secondary metabolite/product.

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Abbreviations

2,4-D:

2,4 Dichlorophenoxiacetic acid

10-DBA III:

10-Deacetylbaccatin III

A:

Alternative

AA:

Ascorbic acid

AHP:

Analytic hierarchy process

BAC III:

Baccatin III

B5:

Gamborg medium

B5 vit:

B5 vitamins

BAP:

6-Benzylaminopurine

CaA:

Casamino acid

CA:

Citric acid

CWI:

Calli weight index

DW:

Dry weight

FW:

Fresh weight

GA3 :

Gibberellic acid

GI:

Growth index

HPLC:

High-performance liquid chromatography

II:

Induction index

Kn:

Kinetin

Glu:

l-Glutamine

MCDM:

Multi-criteria decision making

MI:

Maintenance index

MIL:

B5 medium I for leaves

MIIL:

B5 medium II for leaves

MIS:

B5 medium I for stems

MIIS:

B5 medium II for stems

NAA:

1-Naphthaleneacetic acid

NDA:

Non-dominated alternatives

NDS:

Non-dominated solutions

PVP:

Polyvinylpyrrolidone

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Authors and Affiliations

  1. Division of Molecular Plant Genetics, Department of Agronomy and Plant Breeding, College of Agricultural and Natural Resources, University of Tehran, Karaj, Iran

    Jaber Nasiri, Mohammad Reza Naghavi, Houshang Alizadeh & Mohammad Nabizadeh

  2. Department of Horticultural Sciences, College of Agricultural and Natural Resources, University of Tehran, Karaj, Iran

    Mohammad Reza Fattahi Moghadam

  3. Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, G. C, Evin, Tehran, Iran

    Alireza Mashouf

Authors
  1. Jaber Nasiri
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  2. Mohammad Reza Naghavi
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  3. Houshang Alizadeh
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  4. Mohammad Reza Fattahi Moghadam
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  5. Alireza Mashouf
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  6. Mohammad Nabizadeh
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Correspondence to Jaber Nasiri or Mohammad Reza Naghavi.

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Communicated by M. Capuana.

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Nasiri, J., Naghavi, M.R., Alizadeh, H. et al. Modified AHP-based decision-making model toward accurate selection of eligible maintenance media for production of taxanes in Taxus baccata callus culture. Acta Physiol Plant 37, 110 (2015). https://doi.org/10.1007/s11738-015-1858-z

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  • DOI: https://doi.org/10.1007/s11738-015-1858-z

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