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Advanced engineering and biomimetic materials for bone repair and regeneration

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Abstract

Over the past decade, there has been tremendous progress in developing advanced biomaterials for tissue repair and regeneration. This article reviews the frontiers of this field from two closely related areas, new engineering materials for bone substitution and biomimetic mineralization for bone-like nanocomposites. Rather than providing an exhaustive overview of the literature, we focus on several representative directions. We also discuss likely future trends in these areas, including synthetic biology-enabled biomaterials design and multifunctional implant materials for bone repair and regeneration.

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Authors and Affiliations

  1. Institute of Orthopaedics, Department of Orthopaedic Surgery at the First Affiliated Hospital, Soochow University, Suzhou, 215006, China

    Lei Yang

  2. Research Laboratory of Electronics (RLE), Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139-4307, USA

    Chao Zhong

  3. Synthetic Biology Center, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139-4307, USA

    Chao Zhong

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Correspondence to Lei Yang or Chao Zhong.

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Yang, L., Zhong, C. Advanced engineering and biomimetic materials for bone repair and regeneration. Front. Mater. Sci. 7, 313–334 (2013). https://doi.org/10.1007/s11706-013-0226-4

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