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Laparoscopic Fenestration of Liver Cysts in Polycystic Liver Disease Results in a Median Volume Reduction of 12.5%

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Journal of Gastrointestinal Surgery Aims and scope

Abstract

Introduction

Patients with polycystic liver disease (PCLD) may develop symptoms due to increased liver volume. Laparoscopic fenestration is one of the options to reduce liver volume and to relieve symptoms. This study was performed to evaluate the safety and efficacy of laparoscopic liver cyst fenestration.

Patients and Methods

Twelve patients (all female, median age 45 years, range 35–58) with symptomatic PCLD were included between August 2005 and April 2007. Surgical data were recorded, liver volumes were measured on pre- and postoperative computed tomography (CT) scans, and patients completed a validated symptom-based questionnaire pre- and postoperatively.

Results

Median preoperative liver volume was 4,854 ml (range 1,606–8,201) and decreased to 4,153 ml postoperatively (range 1,556–8,232) resulting in median liver volume reduction of 12.5% (range +9.5 to −24.7%). Median procedural time was 123.5 min (range 50–318), and median hospitalization period was 3.5 days (range 1–8). Postoperative complications occurred in three patients including biliary leakage, obstruction of inferior vena cava and sepsis, all recovering with conservative management. Patients reported decreased symptoms of postprandial fullness and abdominal distension.

Conclusion

Laparoscopic fenestration in PCLD patients results in volume reduction of 12.5% and decrease of symptoms.

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Acknowledgement

We thank the Department of Radiation Oncology of University Medical Centrum St. Radboud, Nijmegen, The Netherlands for support in the liver volume measurements.

Financial support: Joost PH Drenth is a recipient of a ZON-MW VIDI research grant.

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Authors and Affiliations

  1. Department of Medicine, Division of Gastroenterology and Hepatology, University Medical Center St. Radboud, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands

    Loes van Keimpema & Joost P. H. Drenth

  2. Department of Surgery, Jeroen Bosch Hospital, ’s Hertogenbosch, The Netherlands

    Jelle P. Ruurda, Miranda F. Ernst & Hendrikus J. A. A. van Geffen

Authors
  1. Loes van Keimpema
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  2. Jelle P. Ruurda
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  3. Miranda F. Ernst
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  4. Hendrikus J. A. A. van Geffen
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  5. Joost P. H. Drenth
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Correspondence to Loes van Keimpema.

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van Keimpema, L., Ruurda, J.P., Ernst, M.F. et al. Laparoscopic Fenestration of Liver Cysts in Polycystic Liver Disease Results in a Median Volume Reduction of 12.5%. J Gastrointest Surg 12, 477–482 (2008). https://doi.org/10.1007/s11605-007-0376-8

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  • DOI: https://doi.org/10.1007/s11605-007-0376-8

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