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Measurement of liver volume using spiral CT and the curved line and cubic spline algorithms: reproducibility and interobserver variation

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Abstract.

Background: The purpose of this article was to evaluate the accuracy and reproducibility of spiral computed tomography (CT) and the curved line and cubic spline algorithms in measuring liver volume.

Methods: Spiral CT was performed in phantoms, cadaveric liver specimens, and 35 live human subjects (19 healthy volunteers and 16 patients). Images were transferred to a workstation, and volumes were measured by two observers. One observer repeated the measurements at a separate sitting.

Results: The correlation between the CT measurement and the gold standard measurement of the cadaveric livers was very strong (r= 0.94). For the live human subjects, the intraobserver and interobserver correlations were extremely high (r= 0.999 and 0.997, respectively). The mean difference in liver volume measurements between the separate observations was 1%.

Conclusion: The accuracy and reproducibility of this method of assessing liver volume are very high. RID=""ID=""<e5>Correspondence to:</e5> K. K. Kopecky

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Authors and Affiliations

  1. Department of Radiology, Indiana University Hospital, Room 0279, 550 North University Boulevard, Indianapolis, IN 46202-5253, USA, , , , , , US

    K. Sandrasegaran, D. DiGirolamo, S. M. Stockberger, Jr. & K. K. Kopecky

  2. Department of Medicine, Indiana University Hospital, 550 North University Boulevard, Indianapolis, IN 46202-5253, USA, , , , , , US

    P. W. Kwo

  3. Department of Pathology, Indiana University Hospital, 550 North University Boulevard, Indianapolis, IN 46202-5253, USA, , , , , , US

    O. W. Cummings

Authors
  1. K. Sandrasegaran
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  2. P. W. Kwo
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  3. D. DiGirolamo
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  4. S. M. Stockberger, Jr.
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  5. O. W. Cummings
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  6. K. K. Kopecky
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Received: 12 August 1997/Revision accepted: 17 December 1997

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Sandrasegaran, K., Kwo, P., DiGirolamo, D. et al. Measurement of liver volume using spiral CT and the curved line and cubic spline algorithms: reproducibility and interobserver variation. Abdom Imaging 24, 61–65 (1999). https://doi.org/10.1007/s002619900441

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  • DOI: https://doi.org/10.1007/s002619900441

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